Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Zhen-Wang Zhao"'
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-16 (2022)
Abstract Background Asprosin, a newly discovered adipokine, is a C-terminal cleavage product of profibrillin. Asprosin has been reported to participate in lipid metabolism and cardiovascular disease, but its role in atherogenesis remains elusive. Met
Externí odkaz:
https://doaj.org/article/b858dd0a305d4fd5a5f0d45e7457838c
Autor:
Jia-Hui Gao, Lin-Hao He, Xiao-Hua Yu, Zhen-Wang Zhao, Gang Wang, Jin Zou, Feng-Jiao Wen, Li Zhou, Xiang-Jun Wan, Da-Wei Zhang, Chao-Ke Tang
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 12, Pp 2020-2033 (2019)
CXC chemokine ligand 12 (CXCL12) is a member of the CXC chemokine family and mainly acts on cell chemotaxis. CXCL12 also elicits a proatherogenic role, but the molecular mechanisms have not been fully defined yet. We aimed to reveal if and how CXCL12
Externí odkaz:
https://doaj.org/article/b9436f2d4a934963a6e3b4f869282077
Autor:
Wei Xie, Liang Li, Min Zhang, Hai-Peng Cheng, Duo Gong, Yun-Cheng Lv, Feng Yao, Ping-Ping He, Xin-Ping Ouyang, Gang Lan, Dan Liu, Zhen-Wang Zhao, Yu-Lin Tan, Xi-Long Zheng, Wei-Dong Yin, Chao-Ke Tang
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157085 (2016)
Atherosclerotic lesions are lipometabolic disorder characterized by chronic progressive inflammation in arterial walls. Previous studies have shown that macrophage-derived lipoprotein lipase (LPL) might be a key factor that promotes atherosclerosis b
Externí odkaz:
https://doaj.org/article/d0d7866cb1684cd1a3b99f8bb237cc3f
Publikováno v:
Journal of Molecular and Cellular Cardiology. 178:59-67
Publikováno v:
Cell Cycle
The maintenance of cellular cholesterol homeostasis is essential for normal cell function and viability. Excessive cholesterol accumulation is detrimental to cells and serves as the molecular basis of many diseases, such as atherosclerosis, Alzheimer
Autor:
Gang Wang, Jia-Hui Gao, Min Zhang, Xiao-Hua Yu, Da-Wei Zhang, Zhen-Wang Zhao, Xiang-Jun Wan, Chao-Ke Tang, Jin Zou, Li Zhou
Publikováno v:
Journal of Cardiovascular Pharmacology. 77:217-227
Lipid metabolism disorder and inflammatory response are considered to be the major causes of atherosclerogenesis. Astragalin, the most important functional component of flavonoid obtained from persimmon leaves, has the hypolipidemic effects. However,
Autor:
Jia-Hui Gao, Lin-Hao He, Gang Wang, Jin Zou, Shang-Ming Liu, Zhen-Wang Zhao, Li Zhou, Shi-Lin Tang, Chao-Ke Tang, Xiang-Jun Wan
Publikováno v:
Acta Biochimica et Biophysica Sinica. 53:63-71
Myristica fragrans is a traditional herbal medicine and has been shown to alleviate the development of atherosclerosis. However, the anti-atherogenic mechanisms of M. fragrans are still to be addressed. In this study, we explored the effect of M. fra
Autor:
Zhen-Wang Zhao, Gang Wang, Xiaohua Yu, Kong Chen, Chao-Ke Tang, Gao-Feng Zeng, Jin Zou, Da-Wei Zhang
Publikováno v:
Acta Biochimica et Biophysica Sinica. 52:832-841
Interleukin-5 (IL-5) is manifested as its involvement in the process of atherosclerosis, but the mechanism is still unknown. In this study, we explored the effect of IL-5 on lipid metabolism and its underlying mechanisms in THP-1-derived macrophages.
Autor:
Hai-Peng Cheng, Duo Gong, Zhen-Wang Zhao, Ping-Ping He, Xiao-Hua Yu, Qiong Ye, Chong Huang, Xin Zhang, Ling-Yan Chen, Wei Xie, Min Zhang, Liang Li, Xiao-Dan Xia, Xin-Ping Ouyang, Yu-Lin Tan, Zong-bao Wang, Guo-Ping Tian, Xi-Long Zheng, Wei-Dong Yin, Chao-Ke Tang
Publikováno v:
Circulation journal : official journal of the Japanese Circulation Society. 86(2)
Autor:
Chao-Ke Tang, Wei Xie, Duo Gong, Da-Wei Zhang, Xiaoyan Dai, Zhen-Wang Zhao, Liang Li, Weidong Yin, Yun-Cheng Lv, Min Zhang, Xi-Long Zheng, Dongming Guo
Publikováno v:
Atherosclerosis. 289:143-161
Background and aims Kruppel-like factor 14 (KLF14) is known to play a role in atherosclerosis, but the underlying mechanisms are still largely unknown. The aim of our study was to explore the effects of KLF14 on lipid metabolism and inflammatory resp