Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Zhen-Tao Deng"'
Autor:
Zhuohui Zhao, Zhen-Tao Deng, Suling Huang, Mengmeng Ning, Ying Feng, Yu Shen, Qin-Shi Zhao, Ying Leng
Publikováno v:
Nutrients, Vol 14, Iss 12, p 2411 (2022)
Non-alcoholic steatohepatitis (NASH) is a common chronic liver disease worldwide, with no effective therapies available. Discovering lead compounds from herb medicine might be a valuable strategy for the treatment of NASH. Here, we discovered Alisol
Externí odkaz:
https://doaj.org/article/fe19282fbde547c9931e16a90de0d1c2
Publikováno v:
Molecules, Vol 26, Iss 21, p 6516 (2021)
Catharanthus roseus is a well-known traditional herbal medicine for the treatment of cancer, hypertension, scald, and sore in China. Phytochemical investigation on the twigs and leaves of this species led to the isolation of two new monoterpene indol
Externí odkaz:
https://doaj.org/article/241be73c214a4476b95449eb51a3d2c7
Publikováno v:
Designed Monomers and Polymers, Vol 20, Iss 1, Pp 344-350 (2017)
Through metal-free protocol, hypercrosslinked porous polyporphyrin with permanent porosity was obatined via the Friedel–Crafts alkylation of tetracarbazolylporphyrin using formaldehyde dimethyl acetal as an external cross-linker. Its chemical struc
Externí odkaz:
https://doaj.org/article/a26822fac7a045928108c1368d3408cb
Publikováno v:
Organic Chemistry Frontiers. 9:3664-3668
The first total synthesis of two macrocyclic Lycopodium alkaloids, huperserratines A and B, in 12 steps.
Publikováno v:
Chemistrybiodiversity. 19(7)
Five new fawcettimine-type Lycopodium alkaloids, hupertimines A-E (1-5), were discovered from the whole plant of Huperzia serrata, along with two known alkaloids, 8α-hydroxyphlegmariurine B (6) and 8β-hydroxyphlegmariurine B (7). The structures of
Autor:
Li-Hua Su, Zhen-Tao Deng, Xiao-Tong Yang, Tian-Ze Li, Zhen Gao, Xiao-Feng He, Chang-An Geng, Si-Yue Chen, Yun-Bao Ma, Xue-Mei Zhang, Xiao-Yan Huang, Ji-Jun Chen
Publikováno v:
Bioorganic & Medicinal Chemistry. 27:3299-3306
Gastrodia elata is a famous traditional Chinese herb with medicinal and edible application. In this study, nine polybenzyls ( 1 − 9 ), including six new ones ( 2 − 5 , 7 and 9 ), were isolated from the EtOAc extract of G. elata . Five compounds 1
Publikováno v:
Fitoterapia. 132:60-67
Our random bioassay revealed that the CHCl3 part of Chelonopsis praecox (Lamiaceae) showed significant activity against α-glucosidase with the inhibitory rate of 99.6 ± 0.4 % (330 μg/mL). Bioassay-guided isolation yielded seven new ent-kaurane dit
Publikováno v:
Natural Products and Bioprospecting
Three new clerodane-type diterpene glycosides, (5R,6S,8R,9S,10R)-6-O-[β-d-glucopyranosyl-(1 → 4)-α-l-rhamnopyranosyl]cleroda-3,13(16),14-diene (1), (5R,6S,8R,9S,10R,13S)-6-O-[β-d-glucopyranosyl-(1 → 4)-α-l-rhamnopyranosyl]-2-ox-oneocleroda-3,
Publikováno v:
Bioorganicmedicinal chemistry letters. 30(8)
The ent-kaurane diterpenoid chepraecoxin A (CA) obtained in our previous study showed a potential inhibitory activity on α-glucosidase (IC50 274.5 ± 12.5 μM). In order to figure out the structure-activity relationships (SARs), twenty-two derivativ
Publikováno v:
The Journal of Organic Chemistry. 83:10166-10174
The α,β-C(sp3)–H bond dual functionalization of tertiary amines is still a challenging task for both organic and medicinal chemists. Herein a direct, mild, metal-free, and site-specific method mediated by PIDA/I2 was developed for α,β-C(sp3)–