Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Zhen-Li Min"'
Autor:
Cheng-Zhi Gao, Wei Dong, Zhi-Wen Cui, Qiong Yuan, Xia-Min Hu, Qing-Ming Wu, Xianlin Han, Yao Xu, Zhen-Li Min
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 150-162 (2019)
A series of new Olaparib derivatives was designed and synthesized, and their inhibitory activities against poly (ADP-ribose) polymerases-1 (PARP-1) enzyme and cancer cell line MDA-MB-436 in vitro were evaluated. The results showed that compound 5l ex
Externí odkaz:
https://doaj.org/article/5f4681bee0ed4cefb59b2ef92e696960
Autor:
Zhi-Jun Yu, Jing Du, Wei Zhang, Shu-Qi Zhao, Wei Dong, Shi-Qiang Xu, Ling Hu, Zhen-Li Min, Qiong Yuan, Chunxiang Zhang, Xia-Min Hu
Publikováno v:
Journal of Innovative Optical Health Sciences, Vol 12, Iss 6, Pp 1950022-1-1950022-11 (2019)
To investigate the effect of Myocardin-related transcription factor A (MRTF-A) on apoptosis induced by ischemic/reperfusion (I/R), middle cerebral artery occlusion/reperfusion (MCAO/R) in rats were applied to mimic I/R. The neurological deficit score
Externí odkaz:
https://doaj.org/article/45990e1702e04de386eda7c1d7aad4da
Autor:
Ning, Gang1 (AUTHOR), Zhen, Li‐Min1 (AUTHOR), Xu, Wen‐Xiong1 (AUTHOR), Li, Xue‐Jun1 (AUTHOR), Wu, Li‐Na1 (AUTHOR), Liu, Ying1 (AUTHOR), Xie, Chan1 (AUTHOR) happyxiechan@hotmail.com, Peng, Liang1 (AUTHOR) pliang@mail.sysu.edu.cn
Publikováno v:
Journal of Viral Hepatitis. Oct2020, Vol. 27 Issue 10, p1071-1081. 11p.
Autor:
Tong Zhou, Zhen-Li Min, Dan Chen, Rong Liu, Xiao-Lu Cao, Song Liu, Huan-Huan Qin, Guang-Qi Liu
Publikováno v:
Food & Function. 12:1039-1050
Pueraria lobata is utilized as a food source in China. The aim of this study is to combine virtual screening and molecular dynamics predictive model to screen out the potential synaptic plasticity-maintaining components from the root of P. lobate and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::917534bb311d91e12b5ad13293f4da01
https://doi.org/10.1039/d0fo02388d
https://doi.org/10.1039/d0fo02388d
Publikováno v:
Drug Design, Development and Therapy. 14:2517-2534
Purpose The monocarbonyl analogs of curcumin (MCACs) have been widely studied for their promising antitumor activity. Pyrazole is a five-membered aromatic heterocyclic system with various bioactivities incorporated frequently in drugs. However, few o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6988816619d085b8164e7be64929f8dd
https://doi.org/10.2147/dddt.s244865
https://doi.org/10.2147/dddt.s244865
Autor:
Youping Deng, Xiamin Hu, Ling Hu, Mary Qu Yang, Jiankun Huang, Jack Y. Yang, Qiong Yuan, William Yang, Chunxiang Zhang, Zhen-Li Min, Rong Zhang, Yinping Gao, Jing Cheng, Yufei Sun
Publikováno v:
BMC Systems Biology, Vol 12, Iss S7, Pp 1-10 (2018)
BMC Systems Biology
BMC Systems Biology
Background Accumulation of amyloid β-peptide (Aβ) is implicated in the pathogenesis and development of Alzheimer’s disease (AD). Neuron-enriched miRNA was aberrantly regulated and may be associated with the pathogenesis of AD. However, regarding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0adcba0aa1d3b45b2067cf1ac79a93d7
http://link.springer.com/article/10.1186/s12918-018-0633-3
http://link.springer.com/article/10.1186/s12918-018-0633-3
Autor:
Qing Ming Wu, Xianlin Han, Cheng Zhi Gao, Wei Dong, Zhi-wen Cui, Qiong Yuan, Xia Min Hu, Yao Xu, Zhen Li Min
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 150-162 (2019)
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 150-162 (2019)
A series of new Olaparib derivatives was designed and synthesized, and their inhibitory activities against poly (ADP-ribose) polymerases-1 (PARP-1) enzyme and cancer cell line MDA-MB-436 in vitro were evaluated. The results showed that compound 5l ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fbce36d8ee005b81ad76c747f535aa1
http://europepmc.org/articles/PMC6237161
http://europepmc.org/articles/PMC6237161
Autor:
Shi-qiang Xu, Yue Zhu, Chengzhi Gao, Chunxiang Zhang, Ling Hu, Jing Cheng, Zhen-Li Min, Zhiwen Cui, Rong Zhang, Ting-Zi Yin, Wei Zhang, Xiamin Hu
Publikováno v:
Journal of Cellular Biochemistry. 119:7274-7284
Autophagy and apoptosis are involved in the development of a variety of cancers. Fucoxanthin is a natural compound known to have antitumor effects, so we aimed to explore its effects on autophagy and apoptosis in gastric cancer SGC7901 cells. Specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b29204841708349b8f02879af637797e
https://doi.org/10.1002/jcb.27022
https://doi.org/10.1002/jcb.27022
Autor:
Zhijun Yu, Zhen-Li Min, Qiong Yuan, Yue Zhu, Cheng-zhi Gao, Xiamin Hu, Zhi-wen Cui, Wei Dong, Shi-qiang Xu
Publikováno v:
Research on Chemical Intermediates. 44:5107-5122
SHP2 is a new promising target for anti-cancer drug discovery. A series of novel phenylhydrazonopyrazolone derivatives was synthesized by a more convenient method, and their chemical structures were characterized by various spectroscopic methods. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68f154d741c10f42acd74f3b23e40c71
https://doi.org/10.1007/s11164-018-3412-2
https://doi.org/10.1007/s11164-018-3412-2
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