Tamaractam, a New Bioactive Lactam from Tamarix ramosissima, Induces Apoptosis in Rheumatoid Arthritis Fibroblast-Like Synoviocytes

Autor: Yang Niu, Jing Zhao, Huai-Qin Han, Zhen-Hua Miao, Li Weiqi, Li Juan, Xun-Xia Zhao, Yao Yao, Na Sun, Cheng-Shuai Jiang

Publikováno v: Molecules, Vol 22, Iss 1, p 96 (2017)
Molecules; Volume 22; Issue 1; Pages: 96
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry

Chemical investigation of Tamarix ramosissima Ledeb, a traditional herbal medicine used for rheumatoid arthritis (RA) treatment in northwest China, led to the discovery of a new phenolic aromatic rings substituted lactam, tamaractam (1), together wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baacf3edae043f5ff532c1b0c832f106
http://www.mdpi.com/1420-3049/22/1/96

P23 Saikosaponin a ameliorate learning and memory impairment via anti-inflammation effect in an AD mouse model

Autor: Juan Li, Yang Niu, Yao Yao, Zhen-Hua Miao, Sangita Biswas, Li Weiqi, Na Sun

Publikováno v: Biochemical Pharmacology. 139:132

The present study investigated the effects of saikosaponin a (SSA), a natural bioactive compound from Radix bupleuri, on memory deficit and neuroinflammation in the Aβ-treated C57BL/6 mouse model of AD. Different doses of SSA (4, 8, or 16 mg/kg) wer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a3e25ed4edee08ae2bbb83d887009bde
https://doi.org/10.1016/j.bcp.2017.06.024

Molecular Cloning of a Regulatory Protein for Membrane-Bound Guanylate Cyclase GC-A

Autor: Zhen-Hua Miao, Michael Vetter, Janice G. Douglas, Benjamin W. Hughes, Ferid Murad, Danian Che, Nickolai O. Dulin, Zi-Jiang Chen, Chung-Ho Chang, Shiguo Liu

Publikováno v: Biochemical and Biophysical Research Communications. 278:106-111

Activation of membrane-bound guanylate cyclase GC-A by atrial natriuretic factor (ANF) may require the involvement of accessory proteins. To identify these postulated proteins, we isolated a 1.0-kb cDNA clone from a rat brain expression library using

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ae70a4b7a80555eda5a9f858a9aae2
https://doi.org/10.1006/bbrc.2000.3761

Mutational inactivation of the catalytic domain of guanylate cyclase-A receptor

Autor: Dong-Li Song, Chung-Ho Chang, Zhen-Hua Miao, Janice G. Douglas

Publikováno v: Hypertension (Dallas, Tex. : 1979). 25(4 Pt 2)

Abstract Guanylate cyclase-A, the receptor for atrial natriuretic factor, contains a protein kinase–like domain and a catalytic domain in the intracellular region. To investigate the active site (the catalytic cavity) of guanylate cyclase-A, we amp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84b19249f9c82bb010cd0b68aff73af
https://pubmed.ncbi.nlm.nih.gov/7721418

Photoluminescence of Self-Assembled InAs/GaAs Quantum Dots Covered by InAlAs and InGaAs Combination Strain-Reducing Layer.

Autor: Zhi-Dan, Fang, Zheng, Gong, Zhen-Hua, Miao, Xiao-Hua, Xu, Hai-Qiao, Ni, Zhi-Chuan, Niu

Publikováno v: Chinese Physics Letters; Nov2003, Vol. 20 Issue 11, p2061-2063, 3p