Synthesis, Molecular Docking Analysis and Biological Evaluations of Saccharide-Modified Thiadiazole Sulfonamide Derivatives

Autor: Zhen-Bin Han, Jian Wang, Yang Liu, Zuo-Peng Zhang, Hua-sheng Su, Ye Zhong, Maosheng Cheng, Lin Zhou

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 5482, p 5482 (2021)
Volume 22
Issue 11

A series of saccharide-modified thiadiazole sulfonamide derivatives has been designed and synthesized by the “tail approach” and evaluated for inhibitory activity against carbonic anhydrases II, IX, and XII. Most of the compounds showed high topo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::459a227cdfe9d1fdbcb4e235386e5fd1
https://pubmed.ncbi.nlm.nih.gov/34067452