Zobrazeno 1 - 10
of 227
pro vyhledávání: '"Zhen yan Fu"'
Autor:
Yang Li, Shuai Liu, Yong-Tao Wang, Han Min, Dilare Adi, Xiao-Mei Li, Yi-Ning Yang, Zhen yan Fu, Yi-Tong Ma
Publikováno v:
Lipids in Health and Disease, Vol 19, Iss 1, Pp 1-9 (2020)
Abstract Background HMGCR, SCAP, SREBF1, SREBF2 and TBL2 are well-known genes that are involved in the process of lipid metabolism. However, it is not known whether epigenetic changes of these genes are associated with lipid metabolism. In this study
Externí odkaz:
https://doaj.org/article/f449c5058072492f90cb5674ea151f0d
Autor:
Yan-Peng Li, Dilare Adi, Ying-Hong Wang, Yong-Tao Wang, Xiao-Lei Li, Zhen-Yan Fu, Fen Liu, Aibibanmu Aizezi, Jialin Abuzhalihan, Mintao Gai, Xiang Ma, Xiao-mei Li, Xiang Xie, YiTong Ma
Publikováno v:
PeerJ, Vol 11, p e15536 (2023)
Objective The human Disabled-2 (Dab2) protein is an endocytic adaptor protein, which plays an essential role in endocytosis of transmembrane cargo, including low-density lipoprotein cholesterol (LDL-C). As a candidate gene for dyslipidemia, Dab2 is a
Externí odkaz:
https://doaj.org/article/5020e4fba7554056ac93065ba345be38
Autor:
Shuai Liu, Yang Li, Xian Wei, Dilare Adi, Yong-Tao Wang, Min Han, Fen Liu, Bang-Dang Chen, Xiao-Mei Li, Yi-Ning Yang, Zhen-Yan Fu, Yi-Tong Ma
Publikováno v:
PeerJ, Vol 10, p e14590 (2022)
Background Coronary heart disease has become the leading cause of death in developed countries, and dyslipidemia is closely associated with the risk of cardiovascular disease. Dyslipidemia is caused by the abnormal regulation of several genes and sig
Externí odkaz:
https://doaj.org/article/547da64dddf74e2aa5799d0701061f73
Autor:
Min-Tao Gai, Bing Zhu, Xiao-Cui Chen, Fen Liu, Xiang Xie, Xiao-Ming Gao, Xiang Ma, Zhen-Yan Fu, Yi-Tong Ma, Bang-dang Chen
Publikováno v:
Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-9 (2021)
Abstract Background The present study was aimed to establish a prediction model for in-stent restenosis (ISR) in subjects who had undergone percutaneous coronary intervention (PCI) with drug-eluting stents (DESs). Materials and methods A retrospectiv
Externí odkaz:
https://doaj.org/article/6bd156e64e1e4091a80c356a466be8c4
Autor:
Shi-Qi Yan, Dilare Adi, Cheng Liu, Meng-Meng Wang, Jialin Abuzhalihana, Yun Wu, Zhen-Yan Fu, Yi-Ning Yang, Xiao-Mei Li, Xiang Xie, Fen Liu, Bang-Dang Chen, Yi-Tong Ma
Publikováno v:
Hereditas, Vol 158, Iss 1, Pp 1-6 (2021)
Abstract Background FBXW7 gene expression is positively correlated with glycolipid metabolism and is associated with diabetes in animal models. In the current study, we focused on exploring whether genetic variants of the FBXW7 gene were associated w
Externí odkaz:
https://doaj.org/article/a9aebdcfb0484ace92e918661bd97bd8
Autor:
Min-Tao Gai, Dilare Adi, Xiao-Cui Chen, Fen Liu, Xiang Xie, Yi-Ning Yang, Xiao-Ming Gao, Xiang Ma, Zhen-Yan Fu, Yi-Tong Ma, Bang-dang Chen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract PCSK9 plays a crucial role in lipid metabolism. This case–control study explored the associations of novel single nucleotide polymorphisms (SNPs) of the PCSK9 gene with coronary artery disease (CAD) (≥ 1 coronary artery stenosis ≥ 50%)
Externí odkaz:
https://doaj.org/article/b0694c05866e4042840c44b4636c2ac0
Autor:
Dilare Adi, Jialin Abuzhalihan, Jing Tao, Yun Wu, Ying-Hong Wang, Fen Liu, Yi-Ning Yang, Xiang Ma, Xiao-Mei Li, Xiang Xie, Zhen-Yan Fu, Yi-Tong Ma
Publikováno v:
Hereditas, Vol 158, Iss 1, Pp 1-9 (2021)
Abstract Background Coronary artery disease (CAD) is the leading cause of death worldwide. In this study, we aimed to explore whether some genetic variants of the human IDOL gene were associated with CAD among Chinese population in Xinjiang. Methods
Externí odkaz:
https://doaj.org/article/4285592623994e9cb00f32670fc0684c
Autor:
Jing Ming, Xian Wei, Min Han, Dilare Adi, Jialin Abuzhalihan, Yong-Tao Wang, Yi-Ning Yang, Xiao-Mei Li, Xiang Xie, Zhen-Yan Fu, Min-Tao Gai, Yi-Tong Ma
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Dyslipidemia is one of the main risk factors for coronary heart disease (CHD). The E3 ubiquitin ligase which is encoded by the ring finger protein 145 (RNF145) gene is very important in the mediation of cholesterol synthesis and effectively
Externí odkaz:
https://doaj.org/article/beaab26d5c494f819e8806c95b234ce0
Autor:
Jialin Abuzhalihan, Yong-Tao Wang, Yi-Tong Ma, Zhen-Yan Fu, Yi-Ning Yang, Xiang Ma, Xiao-Mei Li, Fen Liu, Bang-Dang Chen
Publikováno v:
Lipids in Health and Disease, Vol 18, Iss 1, Pp 1-6 (2019)
Abstract Background This study was designed to investigate whether differential DNA methylationin of cholesterol absorption candidate genes can function as a biomarker for patients with coronary heart disease (CHD). Methods DNA methylation levels of
Externí odkaz:
https://doaj.org/article/3f70483d31074273b3e265f3a1ab4ec8
Autor:
Fan-Hua Meng, Shuai Liu, Jian Xiao, Yu-Xia Zhou, Le-Wei Dong, Yun-Feng Li, Yan-Qing Zhang, Wei-Hui Li, Ju-Qiong Wang, Yan Wang, Bao-Liang Song, Yi-Tong Ma, Zhen-Yan Fu, Jie Luo
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology.
BACKGROUND: Lower plasma levels of LDL (low-density lipoprotein) cholesterol (LDL-C) can reduce the risk of atherosclerotic cardiovascular disease. The loss-of-function mutations in PCSK9 (proprotein convertase subtilisin/kexin type 9) have been know