Loci at 9p21 and 22q13 harbour alleles for development of cutaneous nevi and melanoma

Autor: Mario, Falchi, Veronique, Bataille, Nicholas, Hayward K., David, Duffy L., Julia, Newton Bishop A., Tomi, Pastinen, Alessandra, Cervino, Zhen, Zhao Z., Panos, Deloukas, Nicole, Soranzo, David, Elder E., Jennifer, Barrett H., Nicholas, Martin G., Timothy, Bishop D., Grant, Montgomery W., Timothy, Spector D.

A high melanocytic nevi count is the strongest known risk factor for cutaneous melanoma. We conducted a genome-wide association study for nevus count using 297,108 SNPs in 1,524 twins, with validation in an independent cohort of 4,107 individuals. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2b7d4a25b760baca9f0e65db30dd8686
https://europepmc.org/articles/PMC3080738/

p53 mutation is common in microsatellite stable, BRAF mutant colorectal cancers.

Autor: Bond CE; Conjoint Gastroenterology Laboratory, Royal Brisbane and Women's Hospital Research Foundation, Clinical Research Centre and the Queensland Institute of Medical Research, Brisbane, Australia. catherine.bond@qimr.edu.au, Umapathy A, Ramsnes I, Greco SA, Zhen Zhao Z, Mallitt KA, Buttenshaw RL, Montgomery GW, Leggett BA, Whitehall VL

Publikováno v: International journal of cancer [Int J Cancer] 2012 Apr 01; Vol. 130 (7), pp. 1567-76. Date of Electronic Publication: 2011 Aug 03.