Zobrazeno 1 - 10
of 2 021
pro vyhledávání: '"Zhen Sheng"'
Autor:
Miaoyan Wei, Rujiao Liu, Yunyun Xu, Xiaobing Chen, Chao Liu, Xueli Bai, Xiaochen Zhang, Shuiping Gao, Jialin Li, Zhen Sheng, Jianpo Lian, Wenliang Wang, Jian Zhang, Si Shi, Jin Xu, Xianjun Yu
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Background Chemotherapy remains the standard first-line treatment for pancreatic adenocarcinoma, but with limited efficacy. We aimed to explore the feasibility of adding the PARP inhibitor fuzuloparib to mFOLFIRINOX in the locally advanced/m
Externí odkaz:
https://doaj.org/article/cef3d052c08f444f99a82d9527d12961
Publikováno v:
IEEE Photonics Journal, Vol 16, Iss 2, Pp 1-5 (2024)
Optimizing doping profiles has always been a key approach to enhance the performance of silicon modulators. Nevertheless, the pursuit of innovative profiles has encountered barriers in recent times. To tackle this issue, the idea of inverse design, w
Externí odkaz:
https://doaj.org/article/6825895979874519a2eb106966ac7296
Publikováno v:
Journal of Orthopaedic Surgery, Vol 31 (2023)
Background Osteoporotic fractures (OFs) are a significant public health issue, which can lead to pain and impaired mobility. The underlying mechanisms of OFs remain unclear, but recent studies have suggested that the circRNA-miRNA-mRNA pathway may pl
Externí odkaz:
https://doaj.org/article/0318df1dda904605a192b77d5ca19a91
Publikováno v:
Statistical Theory and Related Fields, Vol 6, Iss 4, Pp 265-276 (2022)
Due to cost-effectiveness and high efficiency, two-phase case-control sampling has been widely used in epidemiology studies. We develop a semi-parametric empirical likelihood approach to two-phase case-control data under the logistic regression model
Externí odkaz:
https://doaj.org/article/a7542faf8c174d4592676232df2333b9
Autor:
Xi Chen, Lin Shen, Cheng Zhang, Jing Gao, Wenqing Jiang, Zhengyi Wang, Jaeho Jung, Chan Chen, Xuejun Liu, Yanni Zhang, Eunsil Sung, Zhen Sheng, Zhen Meng, Yanling Niu, Chanjuan Liu, Keren Jia, Haiyan Liao, Hyejin Chung, Jingwu Z. Zhang, Andrew X. Zhu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 6 (2023)
Background Claudin18.2 (CLDN18.2) is a tight junction protein that has been identified as a clinically proven target in gastric cancer. Stimulation of 4-1BB with agonistic antibodies is also a promising strategy for immunotherapy and 4-1BB+ T cells w
Externí odkaz:
https://doaj.org/article/58dde64dd10b49928f0d7b67756c8c60
Autor:
Rui Huang, Haiyang Huang, Yingxuan Zhao, Yang Li, XiaoJuan She, Han Liao, Junbo Zhu, Zijian Zhu, Xiang Liu, Hongbao Liu, Zhen Sheng, Fuwan Gan
Publikováno v:
IEEE Photonics Journal, Vol 14, Iss 4, Pp 1-7 (2022)
We experimentally demonstrate a low-loss and low-crosstalk 16-channel 200 GHz-channel-spacing arrayed waveguide grating router (AWGR) with a size of 0.67 × 0.37 mm2, targeting for C-band wavelength division multiplexing (WDM) interconnect routing ap
Externí odkaz:
https://doaj.org/article/1651f774f45f4240b5b589e822f2a877
Autor:
JunBo Zhu, HaiYang Huang, YingXuan Zhao, Yang Li, XiaoJuan She, Han Liao, Rui Huang, ZiJian Zhu, Xiang Liu, Zhen Sheng, FuWan Gan
Publikováno v:
IEEE Photonics Journal, Vol 14, Iss 1, Pp 1-6 (2022)
Wepropose and experimentally demonstrate the ultra-compact mode (de)multiplexers and polarization beam splitter (PBS) based on tapered bent asymmetric directional couplers. The strong coupling strength introduced by tapered bent waveguides significan
Externí odkaz:
https://doaj.org/article/a57ad031997744cfb7a6ad84d89bdbd9
Publikováno v:
Micromachines, Vol 14, Iss 7, p 1435 (2023)
In silicon modulator design, implantation is always a key factor, significantly influencing the doping profile and carrier distribution. As waveguide doping is limited by the compact footprint of the modulator rib, three-dimensional complex optimizat
Externí odkaz:
https://doaj.org/article/74420fce2837450683a4c4e6c1f3f32f
Ultra-Broadband, Compact Arbitrary Ratio Power Splitters Enabled by Adiabatic Sub-Wavelength Grating
Publikováno v:
Photonics, Vol 10, Iss 5, p 578 (2023)
An ultra-broadband, compact and CMOS-compatible arbitrary ratio power splitter that is based on a directional coupler is proposed on the silicon-on-insulator (SOI) platform. The proposed device consists of an adiabatic sub-wavelength grating (ASWG) a
Externí odkaz:
https://doaj.org/article/648e29709a854bd59836efb021557015
Autor:
Yi Huo, Zhen Sheng, Daniel R. Lu, Daniel C. Ellwanger, Chi-Ming Li, Oliver Homann, Songli Wang, Hong Yin, Ruibao Ren
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-16 (2021)
Abstract Background Bi-specific T-cell engager (BiTE) antibody is a class of bispecific antibodies designed for cancer immunotherapy. Blinatumomab is the first approved BiTE to treat acute B cell lymphoblastic leukemia (B-ALL). It brings killer T and
Externí odkaz:
https://doaj.org/article/88b9f96ffc8c48f29c00d36e749723dc