Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Zhen Lun Gu"'
Publikováno v:
Turkish Journal of Forensic Medicine. 28:115-120
OBJECTIVE To study the effects of ketamine and alcohol on learning and memory in mice and its possible mechanism. METHODS Forty mice were divided into 4 groups: normal control group, ketamine group, alcohol group, and alcohol plus ketamine group. Ket
Publikováno v:
Asian Pacific Journal of Cancer Prevention. 14:5805-5810
THis study was conducted to analyze the molecular mechanisms responsible for anti-proliferation effects of glaucocalyxin A in cultured MCF-7 and Hs578T breast cancer cells. The concentration that reduced cell viability to 50% (IC50) after 72 h treatm
Publikováno v:
International Journal of Cardiology. 162:199-209
Background Telomere signaling plays a role in regulating cardiomyocyte apoptosis during cardiac dysfunction. In this study, we investigated the effects of epigallocatechin gallate (EGCG), the major component of polyphenols in green tea, on telomere d
Publikováno v:
Molecular & Cellular Toxicology. 8:187-193
Malignant gliomas are the most common and aggressive primary brain tumor. A major barrier to the treatment of glioma is the drug resistance. The existence of glioma stem cells may be responsible for drug resistance. Recent clinical data show that ars
Publikováno v:
Fitoterapia. 82:383-392
This study aimed to evaluate the radioprotective effect of flavonoids extracted from the seeds of Astragalus complanatus R.Br. (FAC) and their protective mechanism against radiation damage. FAC increased the survival rate of mice and made the damaged
Publikováno v:
Biomedicine & Pharmacotherapy. 64:118-123
In present study, we investigated the effects of aspirin on matrix metalloproteinase (MMP)-9 mRNA expression and release and its possible mechanisms in macrophages derived from THP-1 cells. The macrophages were divided into different groups and treat
Autor:
Zhen-Lun Gu, Rong Han, Zhongqin Liang, Yi Cao, Yan Wang, Jun-Chao Wu, Xiao-Xia Dong, Zheng-Hong Qin
Publikováno v:
European Journal of Neuroscience. 30:2258-2270
The present study sought to investigate mechanisms by which p53 induction contributes to excitotoxic neuronal injury. Rats were intrastriatally administered the N-methyl-D-aspartate (NMDA) receptor agonist quinolinic acid (QA), the changes in the exp
Publikováno v:
Journal of Ethnopharmacology. 123:293-301
Aim of the study Flavonoids extracted from the seeds of Astragalus complanatus R.Br. reduce the proliferation of many cancer cells. The present study was carried out to evaluate the effects of these flavonoids from Astragalus complanatus (FAC) on hum
Publikováno v:
Digestive and Liver Disease. 41:127-133
Background Alcohol is a major cause of fatty liver, the disease is a spectrum that is initiated with steatosis, and without therapy it is apt to develop inflammation, necrosis, fibrosis and finally cirrhosis. There are currently no ideal pharmacologi
Publikováno v:
Planta Medica. 75:113-120
This study was carried out in order to investigate the effects of epigallocatechin gallate (EGCG) on myocardial fibrosis and cell proliferation in cardiac hypertrophy. Cardiac hypertrophy was established in rats by abdominal aortic constriction, and