Zobrazeno 1 - 10
of 215
pro vyhledávání: '"Zhen F Fu"'
Autor:
Caiqian Wang, Yuanyuan Geng, Haoran Wang, Zeheng Ren, Qingxiu Hou, An Fang, Qiong Wu, Liqin Wu, Xiujuan Shi, Ming Zhou, Zhen F Fu, Jonathan F Lovell, Honglin Jin, Ling Zhao
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 6, Pp 1451-1483 (2024)
Abstract Although protein subunit vaccines generally have acceptable safety profiles with precise antigenic content, limited immunogenicity can lead to unsatisfactory humoral and cellular immunity and the need for vaccine adjuvants and delivery syste
Externí odkaz:
https://doaj.org/article/a34d3dfc3d324d818a21353b94f3adc5
Autor:
Zhaochen Luo, Dayong Tian, Ming Zhou, Wenjie Xiao, Yachun Zhang, Mingming Li, Baokun Sui, Wei Wang, Huashi Guan, Huanchun Chen, Zhen F Fu, Ling Zhao
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140586 (2015)
Rabies, caused by rabies virus (RABV), is an acute, fatal encephalitic disease that affects many warm-blooded mammals. Currently, post-exposure prophylaxis regimens are effective for most rabies cases, but once the clinical signs of the disease appea
Externí odkaz:
https://doaj.org/article/ad5ef84021c24996b613b9278b39ef4c
Autor:
Clement W Gnanadurai, Yang Yang, Ying Huang, Zhenguang Li, Christina M Leyson, Tanya L Cooper, Simon R Platt, Stephen B Harvey, Douglas C Hooper, Milosz Faber, Zhen F Fu
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 8, p e0004023 (2015)
METHODOLOGY/PRINCIPAL FINDINGS:The experimental infection of dogs with TriGAS induced high levels of VNA in the serum, whereas wt RABV infection did not. Dogs infected with TriGAS developed antibodies against the virus including its glycoprotein, whe
Externí odkaz:
https://doaj.org/article/d57e5110474d4cc09507b32dd391ed1c
Publikováno v:
Animal Diseases, Vol 4, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/03054c5bccc242d6b9bcb9dba96e3c81
Autor:
Xiaohui Liu, Youtian Yang, Zhaojin Sun, Jing Chen, Jun Ai, Can Dun, Zhen F Fu, Xuefeng Niu, Xiaofeng Guo
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87105 (2014)
The rabies virus (RABV) glycoprotein (G) is the principal antigen responsible for the induction of virus neutralizing antibodies (VNA) and is the major modality of protective immunity in animals. A recombinant RABV HEP-Flury strain was generated by r
Externí odkaz:
https://doaj.org/article/bf12e049554144409eac1bb180978de9
Autor:
Clement W Gnanadurai, Ming Zhou, Wenqi He, Christina M Leyson, Chien-Tsun Huang, Gregory Salyards, Stephen B Harvey, Zhenhai Chen, Biao He, Yang Yang, D C Hooper, Berhnard Dietzchold, Zhen F Fu
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 9, p e2375 (2013)
Rabies is traditionally considered a uniformly fatal disease after onset of clinical manifestations. However, increasing evidence indicates that non-lethal infection as well as recovery from flaccid paralysis and encephalitis occurs in laboratory ani
Externí odkaz:
https://doaj.org/article/bb2a88df811948c59f660ce416db4bff
Autor:
Ming Zhou, Guoqing Zhang, Guiping Ren, Clement W Gnanadurai, Zhenguang Li, Qingqing Chai, Yang Yang, Christina M Leyson, Wenxue Wu, Min Cui, Zhen F Fu
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63384 (2013)
Our previous studies indicated that recombinant rabies viruses (rRABV) expressing chemokines or cytokines (including GM-CSF) could enhance the immunogenicity by recruiting and/or activating dendritic cells (DC). In this study, bacterial flagellin was
Externí odkaz:
https://doaj.org/article/d8e090c61c2648ac92bb2b0b18d427e4
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50144 (2012)
Parainfluenza virus 5 (PIV5), formerly known as simian virus 5 (SV5), is a paramyxovirus often referred to as canine parainfluenza virus (CPI) in the veterinary field. PIV5 is thought to be a contributing factor to kennel cough. Kennel cough vaccines
Externí odkaz:
https://doaj.org/article/d6aa78a0527e4ba194328d6f813c996b
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25414 (2011)
Recently it was found that prior immunization with recombinant rabies virus (RABV) expressing granulocyte-macrophage colony-stimulating factor (GM-CSF) (LBNSE-GM-CSF) resulted in high innate/adaptive immune responses and protection against challenge
Externí odkaz:
https://doaj.org/article/9fad44fc9b444f969c94652b1455bf10
Autor:
Yueming Yuan, An Fang, Haoran Wang, Caiqian Wang, Baokun Sui, Jianqing Zhao, Zhen F. Fu, Ming Zhou, Ling Zhao
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT Infection with neurotropic viruses may result in changes in host behavior, which are closely associated with degenerative changes in neurons. The lyssavirus genus comprises highly neurotropic viruses, including the rabies virus (RABV), which
Externí odkaz:
https://doaj.org/article/c2405ab3063247c9bc6924bd25bc0aae