Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Zhen‐ning Lu"'
Publikováno v:
Phytotherapy Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbd2df977f0d86bd0fef8547c3b1e0bd
https://doi.org/10.1002/ptr.7845
https://doi.org/10.1002/ptr.7845
Publikováno v:
Acta Pharmacol Sin
Liver fibrosis is one of the most severe pathologic consequences of chronic liver diseases, and effective therapeutic strategies are urgently needed. Proton pump inhibitors (PPIs) are H + /K + -ATPase inhibitors and currently used to treat acid-relat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::458131f9956c302ac08ee451dbaf386a
https://doi.org/10.1038/s41401-021-00754-w
https://doi.org/10.1038/s41401-021-00754-w
Publikováno v:
Life sciences. 310
The organic solute transporter α-β (OSTα-OSTβ) is a heteromeric transporter localized to the basolateral membranes of liver, intestinal, and kidney epithelial cells and functions to extrude bile acids and steroids from these tissues. OSTα-OSTβ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab1f5574b9fc051f62a9e0e22ffe46f9
https://pubmed.ncbi.nlm.nih.gov/36270426
https://pubmed.ncbi.nlm.nih.gov/36270426
Autor:
Hongwei He, Mei Zhu, Qi Shan, Guoning Zhang, Zhen-Ning Lu, Zhao Yue, Shang-Jiu Hu, Juxian Wang, Dong‐ke Yu
Publikováno v:
Bioorganicmedicinal chemistry. 49
Liver fibrosis is one of the most common pathological consequences of chronic liver diseases (CLD). To develop effective antifibrotic strategies, a novel class of 1-(substituted phenyl)-1,8-naphthalidine-3-carboxamide derivatives were designed and sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::572e2ab17b9cc460f3ff27b366ccbbcb
https://pubmed.ncbi.nlm.nih.gov/34610571
https://pubmed.ncbi.nlm.nih.gov/34610571
Autor:
Wei-Xiao, Niu, Yun-Yang, Bao, Na, Zhang, Zhen-Ning, Lu, Mao-Xu, Ge, Yi-Ming, Li, Yi, Li, Ming-Hua, Chen, Hong-Wei, He
Publikováno v:
Bioorganic Chemistry. 127:105971
Liver fibrosis is an important process in chronic liver disease and is strongly related to poor prognosis. Dehydromevalonolactone (C8) is a natural product isolated from a fungus of Fusarium sp. CPCC 401218, and its pharmacological activity has never
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f737a6059893e55deca8497b8e87996f
https://doi.org/10.1016/j.bioorg.2022.105971
https://doi.org/10.1016/j.bioorg.2022.105971
Autor:
Hui-Hui Zhang, Ying Zhang, Hong-Yuan Wang, Zhen-Ning Lu, Lu-Gang Yu, Yan-Na Cheng, Fu-Lian Gong, Xiu-Li Guo, Zhao-Peng Liu
Publikováno v:
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
Multidrug resistance (MDR) is one of major obstacles to effective chemotherapeutic treatment of cancer. This study showed that DHPAC, 2-(6-ethoxy-3-(3-ethoxyphenylamino) -1-methyl-1,4-dihydroindeno[1,2-c]pyrazol-7-yloxy) acetamide, a novel compound t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fda2d603c4df3ffef7d13b78b3dd1619
https://doi.org/10.1016/j.biocel.2017.10.012
https://doi.org/10.1016/j.biocel.2017.10.012
Autor:
Dong‐ke Yu, Hong-Tao Liu, Zhen‐ning Lu, Wei-xiao Niu, Ge Maoxu, He Hongwei, Rong-Guang Shao, Bao Yunyang, Na Zhang, Rui Huang
Publikováno v:
Br J Pharmacol
Background and purpose This study investigates the antifibrotic activities and potential mechanisms of costunolide (COS), a natural sesquiterpene compound. Experimental approach Rats subjected to bile duct ligation and mice challenged with CCl4 were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ad8f34d968a8761a642c49e261f3b6
https://pubmed.ncbi.nlm.nih.gov/32133626
https://pubmed.ncbi.nlm.nih.gov/32133626
Publikováno v:
Chemico-biological interactions. 280
Hepatocellular carcinoma (HCC) chemoresistance, which is regarded as a kind of stress management reaction to chemotherapy drugs, severely hinders the therapy outcomes of HCC treatment. Stress management is generally achieved by activating certain sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5288ee5c88d753b8e52b95b977a10a31
https://pubmed.ncbi.nlm.nih.gov/29223570
https://pubmed.ncbi.nlm.nih.gov/29223570
Autor:
Zhao-Yu Shi, Bing Tian, Xiu-Li Guo, Zhao-Jun Hao, Zhen-ning Lu, Yan-Na Cheng, Yanhui Guan, Yi-Fan Dang, Hong-Wei He
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 120, Iss, Pp-(2019)
Resistance to chemotherapeutic agents is a major cause of treatment failure in patients with oral cancer. Proton pump inhibitors (PPIs), essentially H+-K+-ATPase inhibitors which are currently used in the treatment of acid related diseases, have demo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b2536fd061474f51014240147a534c3
https://doi.org/10.1016/j.biopha.2019.109478
https://doi.org/10.1016/j.biopha.2019.109478