Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Zhen‐Yan Li"'
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract Subarachnoid hemorrhage (SAH) is one of the most severe type of cerebral strokes, which can cause multiple cellular changes in the brain leading to neuronal injury and neurological deficits. Specifically, SAH can impair adult neurogenesis in
Externí odkaz:
https://doaj.org/article/926b79a954904a3593af06fe1f6b0997
Autor:
Ri-Xu Liu, Rong-He Gu, Zhi-Peng Li, Zhi-Quan Hao, Qin-Xiao Hu, Zhen-Yan Li, Xiao-Gang Wang, Wang Tang, Xiao-He Wang, Yu-Kai Zeng, Zhen-Wei Li, Qiu Dong, Xiao-Feng Zhu, Di Chen, Ke-Wei Zhao, Rong-Hua Zhang, Zhen-Gang Zha, Huan-Tian Zhang
Publikováno v:
Bone Research, Vol 11, Iss 1, Pp 1-15 (2023)
Abstract Despite the diverse roles of tripartite motif (Trim)-containing proteins in the regulation of autophagy, the innate immune response, and cell differentiation, their roles in skeletal diseases are largely unknown. We recently demonstrated tha
Externí odkaz:
https://doaj.org/article/7e558dc5024546f48cd9b2d8571239a5
Autor:
Chong-Jie Wu, Ri-Xu Liu, Song-Wei Huan, Wang Tang, Yu-Kai Zeng, Jun-Cheng Zhang, Jie Yang, Zhen-Yan Li, Ying Zhou, Zhen-Gang Zha, Huan-Tian Zhang, Ning Liu
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-17 (2022)
Abstract Osteoarthritis (OA) has been recognized as an age-related degenerative disease commonly seen in the elderly that affects the whole “organ” including cartilage, subchondral bone, synovium, and muscles. An increasing number of studies have
Externí odkaz:
https://doaj.org/article/c5aba7b53f7e4128abbe2d3a3e647506
Autor:
Huan‐Tian Zhang, Rui Peng, Sheng Chen, Ao Shen, Lixin Zhao, Wang Tang, Xiao‐He Wang, Zhen‐Yan Li, Zhen‐Gang Zha, Mengmeng Yi, Lingmin Zhang
Publikováno v:
Advanced Science, Vol 9, Iss 29, Pp n/a-n/a (2022)
Abstract Recent evidence has indicated that overexpression of the epigenetic reader bromodomain‐containing protein 4 (BRD4) contributes to a poor prognosis of lung cancers, and the suppression of its expression promotes cell apoptosis and leads to
Externí odkaz:
https://doaj.org/article/d80399557c7f43a3a2c79628430a0283
Autor:
Juan Jiang, Chen Yang, Jia-Qi Ai, Qi-Lei Zhang, Xiao-Lu Cai, Tian Tu, Lily Wan, Xiao-Sheng Wang, Hui Wang, Aihua Pan, Jim Manavis, Wei-Ping Gai, Chong Che, Ewen Tu, Xiao-Ping Wang, Zhen-Yan Li, Xiao-Xin Yan
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Extracellular β-amyloid (Aβ) deposition and intraneuronal phosphorylated-tau (pTau) accumulation are the hallmark lesions of Alzheimer’s disease (AD). Recently, “sorfra” plaques, named for the extracellular deposition of sortilin c-terminal f
Externí odkaz:
https://doaj.org/article/5b526986a2b54f6b9f2e43d6bf886cd3
Autor:
Zhen-Yan Li, Yu-Ling Shi, Guo-Xiong Liang, Jie Yang, Song-Kuan Zhuang, Jie-Bin Lin, Abdelmoumin Ghodbane, Man-Seng Tam, Zu-Jian Liang, Zhen-Gang Zha, Huan-Tian Zhang
Publikováno v:
ACS Omega, Vol 5, Iss 26, Pp 15911-15921 (2020)
Externí odkaz:
https://doaj.org/article/4f1d3d6045fe467a924e1ae65d81d54f
Autor:
Hong-Bin Yan, Yi-Tong Liu, Zhen-Yan Li, Zhuo-Jun Wu, Meng Zhang, Pei-Jun Xue, Yu-Long Liu, Kong-Zhao Wang, Yong-Ming He, Yu Tu, Feng-Mei Cui, Qiu Chen
Publikováno v:
Dose-Response, Vol 18 (2020)
We aimed to determine the toxic effects of tritiated water (HTO) on 12 generations (T1-T12) of human umbilical vein vascular endothelial cells (HUVECs) and elucidate the underlying mechanisms. We evaluated cellular senescence, interleukin (IL) 8 conc
Externí odkaz:
https://doaj.org/article/e05509b22f6045178ef0c651be2a3bb7
Autor:
Xuejuan Gao, Gui-Sheng Xu, Yu-Ning Lin, Qingzhong Zeng, Zhi-Peng Li, Teng Xiao, Yong-Sheng Ye, Zhen-Yan Li
Publikováno v:
Protein & Peptide Letters. 30
Aims: Investigation of the molecular mechanism of tripartite motif 21 (TRIM21) in osteosarcoma (OS) would shed light on the understanding of the pathogenesis of OS. Background: OS is the most frequent malignant bone tumor with a poor prognosis. TRIM2
Autor:
Ri-Xu Liu, Wang Tang, Bo-Yuan Zheng, Yong Yang, Zhen-Yan Li, Tao Gui, Huan-Tian Zhang, Ning Liu, Zhen-Gang Zha, Jing-Xiang Li
Publikováno v:
Biochemical and Biophysical Research Communications. 590:20-26
Chondrosarcoma (CHS) is the second most common bone malignant tumor and currently has limited treatment options. We have recently demonstrated that thioredoxin interacting protein (TXNIP) plays a crucial role in the oncogenesis of bone sarcoma, yet i
Autor:
Wang Tang, Zhen-Wei Li, Gui-Qiang Miao, Zhi-Peng Li, Tao Gui, Chong-Jie Wu, Zhen-Yan Li, Jie Yang, Xiao-Dong Zhao, Ning Liu, Zhen-Gang Zha, Lu-Tian Yao, Huan-Tian Zhang
Publikováno v:
Journal of Inflammation Research.
Wang Tang1 *, Zhen-Wei Li1 *, Gui-Qiang Miao2 *, Zhi-Peng Li,1 Tao Gui,1 Chong-Jie Wu,1 Zhen-Yan Li,1 Jie Yang,1 Xiao-Dong Zhao,2 Ning Liu,1 Zhen-Gang Zha,1 Lu-Tian Yao,3 Huan-Tian Zhang1 1Department of Bone and Joint Surgery, The First A