Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Zhen‐Xia Chen"'
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 21, Iss 3, Pp 589-600 (2023)
In the evolutionary model of dosage compensation, per-allele expression level of the X chromosome has been proposed to have twofold up-regulation to compensate its dose reduction in males (XY) compared to females (XX). However, the expression regulat
Externí odkaz:
https://doaj.org/article/3b5fa495396d4cf2ac706b591f387ad7
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract G-quadruplex (G4) is a four-stranded helical DNA secondary structure formed by guanine-rich sequence folding, and G4 has been computationally predicted to exist in a wide range of species. Substantial evidence has supported the formation of
Externí odkaz:
https://doaj.org/article/450442d20cb54c358f97869b42e83738
Autor:
Ling Wang, Yi‐Xuan Tu, Lu Chen, Ke‐Chun Yu, Hong‐Kai Wang, Shu‐Qiao Yang, Yuan Zhang, Shuai‐Jie Zhang, Shuo Song, Hong‐Li Xu, Zhu‐Cheng Yin, Ming‐Qian Feng, Jun‐Qiu Yue, Xiang‐Hong Huang, Tang Tang, Shao‐Zhong Wei, Xin‐Jun Liang, Zhen‐Xia Chen
Publikováno v:
iMeta, Vol 3, Iss 1, Pp n/a-n/a (2024)
Abstract Consumption of dietary fiber and anthocyanin has been linked to a lower incidence of colorectal cancer (CRC). This study scrutinizes the potential antitumorigenic attributes of a black rice diet (BRD), abundantly rich in dietary fiber and an
Externí odkaz:
https://doaj.org/article/8c5f9a7b6831453387bd74e3f3c57978
Autor:
Ling Wang, Yi‐Xuan Tu, Lu Chen, Yuan Zhang, Xue‐Ling Pan, Shu‐Qiao Yang, Shuai‐Jie Zhang, Sheng‐Hui Li, Ke‐Chun Yu, Shuo Song, Hong‐Li Xu, Zhu‐Cheng Yin, Jun‐Qiu Yue, Qian‐Lin Ni, Tang Tang, Jiu‐Liang Zhang, Min Guo, Shuai Zhang, Fan Yao, Xin‐Jun Liang, Zhen‐Xia Chen
Publikováno v:
Advanced Science, Vol 10, Iss 25, Pp n/a-n/a (2023)
Abstract Men demonstrate higher incidence and mortality rates of colorectal cancer (CRC) than women. This study aims to explain the potential causes of such sexual dimorphism in CRC from the perspective of sex‐biased gut microbiota and metabolites.
Externí odkaz:
https://doaj.org/article/e22dbba19fa84e1180d336d3fe5192d6
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-24 (2022)
Abstract Background Pseudogenes are excellent markers for genome evolution, which are emerging as crucial regulators of development and disease, especially cancer. However, systematic functional characterization and evolution of pseudogenes remain la
Externí odkaz:
https://doaj.org/article/9373413f3f694e788b61eedb7a81e574
Publikováno v:
Advanced Science, Vol 9, Iss 36, Pp n/a-n/a (2022)
Abstract Maintenance and differentiation of germline stem and progenitor cells (GSPCs) is important for sexual reproduction. Here, the authors identify zebrafish pld6 as a novel germline‐specific gene by cross‐analyzing different RNA sequencing r
Externí odkaz:
https://doaj.org/article/7d1cb96efc964a77bda011c54855c677
Autor:
Ding Ye, Yi-Xuan Tu, Houpeng Wang, Mudan He, Yaqing Wang, Zhengfang Chen, Zhen-Xia Chen, Yonghua Sun
Publikováno v:
Water Biology and Security, Vol 1, Iss 3, Pp 100059- (2022)
Zebrafish (Danio rerio) has been used as a promising animal model to study gonadal development and gametogenesis. Although previous studies have identified critical molecules participating in zebrafish gonad differentiation, a landscape view of the b
Externí odkaz:
https://doaj.org/article/9c8b985e0fd94d79958b79a14c174605
Autor:
Lin Chen, Zhihui Luo, Chen Zhao, Qinglan Li, Yingjie Geng, Yong Xiao, Ming‐Kai Chen, Lianyun Li, Zhen‐Xia Chen, Min Wu
Publikováno v:
Advanced Science, Vol 9, Iss 23, Pp n/a-n/a (2022)
Abstract Inflammation is one of the critical risk factors for colorectal cancer (CRC). However, the mechanisms for transition from colitis to CRC remain elusive. Recently, epigenetic changes have emerged as important regulatory factors for colitis‐
Externí odkaz:
https://doaj.org/article/677ae405d97045818513c457027b152a
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-14 (2020)
Abstract Background Many disease causing genes have been identified through different methods, but there have been no uniform annotations of biomedical named entity (bio-NE) of the disease phenotypes of these genes yet. Furthermore, semantic similari
Externí odkaz:
https://doaj.org/article/07bf2a498036484faeda77607ab03d9b
Autor:
Lu Chen, Li Wang, Qiwei Cheng, Yi-Xuan Tu, Zhuang Yang, Run-Ze Li, Zhi-Hui Luo, Zhen-Xia Chen
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background Early sex differentiation genes of zebrafish remain an unsolved mystery due to the difficulty to distinguish the sex of juvenile zebrafish. However, aromatase inhibitors (AIs) could direct juvenile zebrafish sex differentiation to
Externí odkaz:
https://doaj.org/article/2990114eafaf43b2b7463dbc27384850