Sigma 1 Receptor, Cholesterol and Endoplasmic Reticulum Contact Sites.

Autor: Zhemkov V; Department of Physiology, UT Southwestern Medical Center at Dallas, Texas, United States., Liou J; Department of Physiology, UT Southwestern Medical Center at Dallas, Texas, United States., Bezprozvanny I; Department of Physiology, UT Southwestern Medical Center at Dallas, Texas, United States.; Laboratory of Molecular Neurodegeneration, Peter the Great St Petersburg State Polytechnic University, Russia.

Publikováno v: Contact (Thousand Oaks (Ventura County, Calif.)) [Contact (Thousand Oaks)] 2021 Jul 11; Vol. 4, pp. 25152564211026505. Date of Electronic Publication: 2021 Jul 11 (Print Publication: 2021).

Sigma-1 Receptor (S1R) Interaction with Cholesterol: Mechanisms of S1R Activation and Its Role in Neurodegenerative Diseases.

Autor: Zhemkov V; Department of Physiology, UT Southwestern Medical Center, Dallas, TX 75390, USA., Geva M; Prilenia Therapeutics Development LTD, Herzliya 4673304, Israel., Hayden MR; Prilenia Therapeutics Development LTD, Herzliya 4673304, Israel.; Centre for Molecular Medicine and Therapeutics, The University of British Columbia, Vancouver, BC V6H 3V5, Canada., Bezprozvanny I; Department of Physiology, UT Southwestern Medical Center, Dallas, TX 75390, USA.; Laboratory of Molecular Neurodegeneration, Peter the Great St Petersburg State Polytechnic University, 195251 St. Petersburg, Russia.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2021 Apr 15; Vol. 22 (8). Date of Electronic Publication: 2021 Apr 15.

Comprehensive Analysis of Age- and Sex-Related Expression of the Chaperone Protein Sigma-1R in the Mouse Brain.

Autor: Tarmoun, Khadija^1,2 (AUTHOR), Lachance, Véronik^1,2 (AUTHOR) lachance.veronik@uqam.ca, Le Corvec, Victoria^1,2 (AUTHOR), Bélanger, Sara-Maude^1,2 (AUTHOR), Beaucaire, Guillaume^1,2 (AUTHOR), Kourrich, Saïd^1,2,3 (AUTHOR) lachance.veronik@uqam.ca

Publikováno v: Brain Sciences (2076-3425). Sep2024, Vol. 14 Issue 9, p881. 18p.

Light-sheet microscopy of cleared tissues with isotropic, subcellular resolution.

Autor: Chakraborty T; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Lyda Hill Department of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, TX, USA., Driscoll MK; Lyda Hill Department of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, TX, USA., Jeffery E; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA., Murphy MM; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA., Roudot P; Lyda Hill Department of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, TX, USA., Chang BJ; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Lyda Hill Department of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, TX, USA., Vora S; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA., Wong WM; Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX, USA., Nielson CD; Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX, USA., Zhang H; Department of Physiology, University of Texas Southwestern Medical Center, Dallas, TX, USA., Zhemkov V; Department of Physiology, University of Texas Southwestern Medical Center, Dallas, TX, USA., Hiremath C; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA., De La Cruz ED; Department of Biological Sciences, Columbia University, New York, NY, USA., Yi Y; Department of Restorative Sciences, Texas A&M University, College Station, TX, USA., Bezprozvanny I; Department of Physiology, University of Texas Southwestern Medical Center, Dallas, TX, USA., Zhao H; Department of Restorative Sciences, Texas A&M University, College Station, TX, USA., Tomer R; Department of Biological Sciences, Columbia University, New York, NY, USA.; NeuroTechnology Center, Columbia University, New York, NY, USA.; Data Science Institute, Columbia University, New York, NY, USA., Heintzmann R; Leibniz Institute of Photonic Technology, Jena, Germany.; Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University, Jena, Germany., Meeks JP; Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX, USA., Marciano DK; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA., Morrison SJ; Children's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Danuser G; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Lyda Hill Department of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, TX, USA., Dean KM; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA. Kevin.Dean@utsouthwestern.edu., Fiolka R; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA. Reto.Fiolka@utsouthwestern.edu.; Lyda Hill Department of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, TX, USA. Reto.Fiolka@utsouthwestern.edu.

Publikováno v: Nature methods [Nat Methods] 2019 Nov; Vol. 16 (11), pp. 1109-1113. Date of Electronic Publication: 2019 Oct 31.

Neuronal Sigma-1 Receptors: Signaling Functions and Protective Roles in Neurodegenerative Diseases.

Autor: Ryskamp DA; Department of Physiology, UT Southwestern Medical Center at Dallas, Dallas, TX, United States., Korban S; Laboratory of Molecular Neurodegeneration, Peter the Great St. Petersburg State Polytechnic University, Saint Petersburg, Russia., Zhemkov V; Department of Physiology, UT Southwestern Medical Center at Dallas, Dallas, TX, United States., Kraskovskaya N; Laboratory of Molecular Neurodegeneration, Peter the Great St. Petersburg State Polytechnic University, Saint Petersburg, Russia., Bezprozvanny I; Department of Physiology, UT Southwestern Medical Center at Dallas, Dallas, TX, United States.; Laboratory of Molecular Neurodegeneration, Peter the Great St. Petersburg State Polytechnic University, Saint Petersburg, Russia.

Publikováno v: Frontiers in neuroscience [Front Neurosci] 2019 Aug 28; Vol. 13, pp. 862. Date of Electronic Publication: 2019 Aug 28 (Print Publication: 2019).