Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Zhejiu Quan"'
Autor:
Eul Sik Jung, Ji Hun Kim, Mi-Yoon Chang, Wonjun Hong, Zhejiu Quan, Seung Hyun Kim, Seungkwon You, Dae-Sung Kim, Jiho Jang, Sang-Hun Lee, Hyongbum Henry Kim, Hoon Chul Kang
Publikováno v:
Stem Cell Research, Vol 59, Iss , Pp 102664- (2022)
X-linked adrenoleukodystrophy (ALD) caused by the ABCD1 mutation, is the most common inherited peroxisomal disease. Previously, we generated an ALD patient-derived SCHi001-A iPSC model. In this study, we have performed the first genome editing of ALD
Externí odkaz:
https://doaj.org/article/5d11b80c4cb347fb883062844b1ab6e8
Publikováno v:
Stem Cell Research, Vol 25, Iss C, Pp 46-49 (2017)
X-linked adrenoleukodystrophy (X-ALD) is an inherited disorder caused by a mutation in the ATP-binding cassette transporter subfamily D member 1 (ABCD1) gene. We generated two induced pluripotent stem cell (iPSC) lines from X-ALD patients with adreno
Externí odkaz:
https://doaj.org/article/97d62e039d7944cea5417df0b86436d9
Autor:
Jae Woo Choi, Seonwoo Min, Jinman Park, Hyewon Jang, Hui Kwon Kim, Younggwang Kim, Zhejiu Quan, Sungroh Yoon, Sang-Yeon Seo, Jeong Hong Shin, Ji Hun Kim, Hoon Chul Kang, Sungtae Lee, Myungjae Song, Hyongbum Kim
Publikováno v:
Nature Biotechnology. 38:1037-1043
Base editors, including adenine base editors (ABEs)1 and cytosine base editors (CBEs)2,3, are widely used to induce point mutations. However, determining whether a specific nucleotide in its genomic context can be edited requires time-consuming exper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4d79516b1adad6b04a9cde2a233c445
https://doi.org/10.1038/s41587-020-0573-5
https://doi.org/10.1038/s41587-020-0573-5
Autor:
Hoon Chul Kang, Jiho Jang, Zhejiu Quan, Sang-Hun Lee, Eul Sik Jung, Seung Hyun Kim, Wonjun Hong, Dae-Sung Kim, Seungkwon You, Ji Hun Kim, Mi-Yoon Chang, Hyongbum Kim
X-linked adrenoleukodystrophy (ALD) caused by the ABCD1 mutation, is the most common inherited peroxisomal disease. It is characterized by three phenotypes: inflammatory cerebral demyelination, progressive myelopathy, and adrenal insufficiency, but t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f824418b23d8258f8c74247cd0336533
https://doi.org/10.1101/2020.02.23.962118
https://doi.org/10.1101/2020.02.23.962118
Autor:
Joon Soo Lee, Heung Dong Kim, Hyun Woo Kim, Zhejiu Quan, Minjung Cho, Young Rang Yoo, Eunji Cheong, Jiho Jang, Yang In Kim, Ji Hun Kim, Dae Sung Kim, Hoon Chul Kang, Young Beom Kim
Publikováno v:
Brain and Development. 40:287-298
Background We investigated how two distinct mutations in SCN1A differentially affect electrophysiological properties of the patient-derived GABAergic neurons and clinical severities in two Dravet syndrome (DS) patients. Materials and Methods We estab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d29d43849ab87d13a34be6722d0f22
https://doi.org/10.1016/j.braindev.2017.12.002
https://doi.org/10.1016/j.braindev.2017.12.002
Publikováno v:
Stem Cell Research, Vol 25, Iss C, Pp 46-49 (2017)
X-linked adrenoleukodystrophy (X-ALD) is an inherited disorder caused by a mutation in the ATP-binding cassette transporter subfamily D member 1 (ABCD1) gene. We generated two induced pluripotent stem cell (iPSC) lines from X-ALD patients with adreno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b80630979c91f61821e74c849c7f264c
https://doi.org/10.1016/j.scr.2017.10.003
https://doi.org/10.1016/j.scr.2017.10.003
Autor:
Zhejiu Quan, Yoonhee Jin, Dong Seok Kim, Jung Seung Lee, Yeeun Choi, Eunji Cheong, Hyong Pyo Kim, Sung Rae Cho, Seung Woo Cho, Soohyun Wi, Yun-Gon Kim, Sungjin Min, Jin Kim, Da Hee Ahn, Ji Hea Yu, Hoon Chul Kang, Ann Na Cho, Hyun Woo Kim, Gyeong Eon Chang, Yonghwan Kim
Publikováno v:
Nature biomedical engineering. 2(7)
Biophysical cues can improve the direct reprogramming of fibroblasts into neurons that can be used for therapeutic purposes. However, the effects of a three-dimensional (3D) environment on direct neuronal reprogramming remain unexplored. Here, we sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12bcbbaff64e41693ecfd984fddf9162
https://pubmed.ncbi.nlm.nih.gov/30948831
https://pubmed.ncbi.nlm.nih.gov/30948831
Autor:
Sang Gu Kang, Meihua Jin, Nam Kyung Hwang, Zhejiu Quan, Tae Chul Moon, Chang Xin Lin, Hyeun Wook Chang, Eunkyung Lee
Publikováno v:
Biological and Pharmaceutical Bulletin. 31:1663-1666
Ym1 and Ym2 (Ym1/2) are chitinase-like proteins and we reported previously that IL-4 induced Ym1/2 in mouse bone marrow-derived mast cells. In the present study, ovalbumin-induced asthmatic mice were used to investigate the effect of glucocorticoids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87392f578cafe5db9eccd22d76798967
https://doi.org/10.1248/bpb.31.1663
https://doi.org/10.1248/bpb.31.1663
Autor:
Hyun Pyo Kim, Jeongsoo Kim, Tae Chul Moon, Makodo Murakami, Hyeun Wook Chang, Haeil Park, Zhejiu Quan, Ichiro Kudo
Publikováno v:
Bioorganic & Medicinal Chemistry. 15:7138-7143
Several prototypes of C–C biflavones ( a – f ) were synthesized and evaluated their inhibitory activity against phospholipase A 2 s (PLA 2 s) activity. The synthetic C–C biflavones ( a – f ) showed rather different inhibitory activity against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8b4d739037e30787bf10fdba08c0ad
https://doi.org/10.1016/j.bmc.2007.07.054
https://doi.org/10.1016/j.bmc.2007.07.054
Autor:
Meihua Jin, Se-Jong Kim, Kun Ho Son, Ju Hye Yang, Jong Kun Son, Eunkyung Lee, Tae Chul Moon, Zhejiu Quan, Hyeun Wook Chang, Kil-Ung Kim
Publikováno v:
Archives of Pharmacal Research. 29:874-878
Methyl gallate (MG) is a medicinal herbal product that is isolated from Paeonia lactiflora that inhibits cyclooxygenase-2 (COX-2) dependent phases of prostaglandin D2 (PGD2) generation in bone marrow-derived mast cells (BMMC) in a concentration-depen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e84d0cbded07ff2dd95b33f1ddaeb5bf
https://doi.org/10.1007/bf02973908
https://doi.org/10.1007/bf02973908