Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Zhefeng Guo"'
Publikováno v:
ACS Omega, Vol 5, Iss 34, Pp 21497-21505 (2020)
Externí odkaz:
https://doaj.org/article/ddfd6f6d7cc34096a92f2ef9625547d4
Autor:
Jingzhou Wang, Giovanna Park, Yoon Kyung Lee, Matthew Nguyen, Tiffany San Fung, Tiffany Yuwen Lin, Frederick Hsu, Zhefeng Guo
Publikováno v:
ACS Omega, Vol 5, Iss 11, Pp 5984-5993 (2020)
Externí odkaz:
https://doaj.org/article/b457e37368ee487b902ce0f019101267
Publikováno v:
Royal Society Open Science, Vol 8, Iss 3 (2021)
Amyloid formation is involved in a wide range of neurodegenerative diseases including Alzheimer's and prion diseases. Structural understanding of the amyloid is critical to delineate the mechanism of aggregation and its pathological spreading. Site-d
Externí odkaz:
https://doaj.org/article/e6862e0feff14956b165eaa12cbe30d3
Publikováno v:
ACS Omega, Vol 3, Iss 7, Pp 8401-8407 (2018)
Externí odkaz:
https://doaj.org/article/68051f6898f648ebbc80e00c1b320662
Autor:
Zhefeng Guo
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 8, Pp 1562-1563 (2021)
Externí odkaz:
https://doaj.org/article/680bc19314a048e79e574fc1d3707b3c
Publikováno v:
Royal Society Open Science, Vol 6, Iss 7 (2019)
Amyloid-β (Aβ) oligomers play a central role in the pathogenesis of Alzheimer's disease. Oligomers of different sizes, morphology and structures have been reported in both in vivo and in vitro studies, but there is a general lack of understanding a
Externí odkaz:
https://doaj.org/article/48819e3287fc417bbd25f9a7bf49f9c6
Publikováno v:
Royal Society Open Science, Vol 5, Iss 7 (2018)
Deposition of amyloid fibrils is a pathological hallmark of Alzheimer's disease. Aβ42 is the major protein whose aggregation leads to the formation of these fibrils. Understanding the detailed structure of Aβ42 fibrils is of particular importance f
Externí odkaz:
https://doaj.org/article/5f5d0c5be02a4ca98a7f33fae3e3e3cb
Publikováno v:
Royal Society Open Science, Vol 4, Iss 1 (2017)
Formation of amyloid fibrils underlies a wide range of human disorders, including Alzheimer's and prion diseases. The amyloid fibrils can be readily detected thanks to thioflavin T (ThT), a small molecule that gives strong fluorescence upon binding t
Externí odkaz:
https://doaj.org/article/f7f5f965ab224da69390bf6ef833aab6
Publikováno v:
Royal Society Open Science, Vol 4, Iss 8 (2017)
Aggregation of amyloid-β (Aβ) protein plays a central role in Alzheimer's disease. Because protein aggregation is a concentration-dependent process, rigorous investigations require accurate concentration measurements. Owing to the high aggregation
Externí odkaz:
https://doaj.org/article/9d5a1538f7db4c1395301072e15bdff2
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47248 (2012)
Amyloid fibril formation is associated with a range of neurodegenerative diseases in humans, including Alzheimer's, Parkinson's, and prion diseases. In yeast, amyloid underlies several non-Mendelian phenotypes referred to as yeast prions. Mechanism o
Externí odkaz:
https://doaj.org/article/f7a9dee1ab054dd68101fced4af95ed6