Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Zhee Sheen Wong"'
Autor:
Emily F. Merritt, Hannah J. Johnson, Zhee Sheen Wong, Adam S. Buntzman, Austin C. Conklin, Carla M. Cabral, Casey E. Romanoski, Jon P. Boyle, Anita A. Koshy
Publikováno v:
mSphere, Vol 5, Iss 5 (2020)
ABSTRACT Toxoplasma gondii’s tropism for and persistence in the central nervous system (CNS) underlies the symptomatic disease that T. gondii causes in humans. Our recent work has shown that neurons are the primary CNS cell with which Toxoplasma in
Externí odkaz:
https://doaj.org/article/8ec6668ebe26445abbe5da52c08286cf
Publikováno v:
PLoS Pathogens, Vol 16, Iss 6, p e1008528 (2020)
Toxoplasma gondii and Hammondia hammondi are closely-related coccidian intracellular parasites that differ in their ability to cause disease in animal and (likely) humans. The role of the host response in these phenotypic differences is not known and
Externí odkaz:
https://doaj.org/article/de95e4da367c46b1bcc6cd4fffaa3dd8
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25430 (2011)
The outcome of microbial infection of insects is dependent not only on interactions between the host and pathogen, but also on the interactions between microbes that co-infect the host. Recently the maternally inherited endosymbiotic bacteria Wolbach
Externí odkaz:
https://doaj.org/article/83e1c44555d141178c8ac3d7ddaad5ce
Autor:
Anita A. Koshy, Casey E. Romanoski, Adam Buntzman, Hannah J. Johnson, Emily F. Merritt, Austin C. Conklin, Zhee Sheen Wong, Jon P. Boyle, Carla M. Cabral
Publikováno v:
mSphere
mSphere, Vol 5, Iss 5 (2020)
mSphere, Vol 5, Iss 5 (2020)
Like other persistent intracellular pathogens, Toxoplasma gondii, a protozoan parasite, has evolved to evade the immune system and establish a chronic infection in specific cells and organs, including neurons in the CNS. Understanding T. gondii’s p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99eabf0584626b1f00eb9e368e9c2f29
http://europepmc.org/articles/PMC7471001
http://europepmc.org/articles/PMC7471001
Publikováno v:
Virology. 502:20-27
Small non-coding microRNAs (miRNAs) can modulate the outcome of virus infection. Here we explore the role of miRNAs in insect-virus interactions, in vivo, using the natural Drosophila melanogaster-Drosophila C virus (DCV) model system. Comparison of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::887eadd5caa393078bc21ff9e25fe8af
https://doi.org/10.1016/j.virol.2016.12.009
https://doi.org/10.1016/j.virol.2016.12.009
Publikováno v:
Int J Parasitol
Toxoplasma gondii is remarkably unique in its ability to successfully infect vertebrate hosts from multiple phyla and can successfully infect most cells within these organisms. The infection outcome in each of these species is determined by the compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f24aee8e289a6cabd574256d310949c6
https://pubmed.ncbi.nlm.nih.gov/32407716
https://pubmed.ncbi.nlm.nih.gov/32407716
Publikováno v:
Methods in Molecular Biology ISBN: 9781493998562
Methods Mol Biol
Methods Mol Biol
Toxoplasma gondii tachyzoites and bradyzoites are studied extensively in the laboratory due to the ease with which they can be cultured. In contrast oocysts and the sporozoites within them are more difficult to work with, in that cat infections are r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3270a6de5c4a519fa340b5a50c95a1a5
https://doi.org/10.1007/978-1-4939-9857-9_4
https://doi.org/10.1007/978-1-4939-9857-9_4
Publikováno v:
Journal of General Virology. 97:1446-1452
Elevated levels of reactive oxygen species (ROS) provide protection against virus-induced mortality in Drosophila. In addition to contributing to oxidative stress, ROS are known to activate a number of signalling pathways including the extracellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9535a350de6d85416f803be9886b68
https://doi.org/10.1099/jgv.0.000456
https://doi.org/10.1099/jgv.0.000456
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 6, p e1008528 (2020)
PLoS Pathogens, Vol 16, Iss 6, p e1008528 (2020)
Toxoplasma gondii and Hammondia hammondi are closely-related coccidian intracellular parasites that differ in their ability to cause disease in animal and (likely) humans. The role of the host response in these phenotypic differences is not known and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb864133849931f4a8018cdf00eb43e
https://doi.org/10.1371/journal.ppat.1008528
https://doi.org/10.1371/journal.ppat.1008528
Autor:
Jon P. Boyle, Jitender P. Dubey, Shiv K. Verma, Sarah L Sokol, Abby S. Primack, Zhee Sheen Wong, Sethu C. Nair, Maiwase Tembo, Camila K. Cerqueira-Cézar
Publikováno v:
eLife
eLife, Vol 7 (2018)
eLife, Vol 7 (2018)
Most eukaryotic parasites are obligately heteroxenous, requiring sequential infection of different host species in order to survive. Toxoplasma gondii is a rare exception to this rule, having a uniquely facultative heteroxenous life cycle. To underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0266d1c6a7935fc3a180249b4aa640b1
http://europepmc.org/articles/PMC5963921
http://europepmc.org/articles/PMC5963921