Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Zhechu Peng"'
Autor:
Eileen X. Stiles, Jingyu Chen, Joshua Silva, Chien-Yu Chen, Ni Zeng, Mario M. Alba, Richa Aggarwal, Handan Hong, Bangyan L. Stiles, Anketse Debebe, Zhechu Peng, Taojian Tu, Lina He
Publikováno v:
Am J Pathol
High circulating lipids occurring in obese individuals and insulin-resistant patients are considered a contributing factor to type 2 diabetes. Exposure to high lipid concentration is proposed to both protect and damage beta-cells under different circ
Autor:
Laura Viviani, Kirsty Reid, Thierry Gastineau, Catherine Milne, Dean Smith, Robin Levis, Dianliang Lei, Mark van Ooij, Philippe Alexandre Gilbert, Joris Vandeputte, Jianxun Xie, Leena Madhuri, Shahjahan Shaid, Vaughn Kubiak, Rajinder Suri, Takuo Mizukami, Yoshihisa Shirasaki, Xiantang Li, Ying-Ying Zhou, Alla Trapkova, Sunil Goel, Jai Prakash, Amrullah Aninditio Subagio, Eniek Suwarni, Kyung Jin Jung, Gautam Sanyal, Pradip Das, Emmanuelle Coppens, David Wright, Zhechu Peng, Helle Northeved, Carmen Jungbäck, Tatiana Kirpitchenok, Lorenzo Del Pace, Borami Seo, Brinda Poojary, Antoniana Ottoni
Publikováno v:
Biologicals : journal of the International Association of Biological Standardization. 78
This online workshop Accelerating Global Deletion of the Abnormal Toxicity Test for vaccines and biologicals. Planning common next steps was organized on October 14th, 2021, by the Animal Free Safety Assessment Collaboration (AFSA), the Humane Societ
Autor:
Zhechu Peng, Richa Aggarwal, Chien-Yu Chen, Ni Zeng, Eileen X. Stiles, Anketse Debebe, Bangyan L. Stiles, Lina He, Jingyu Chen, Joshua Silva
High circulating lipids occurring in obese individuals and insulin resistant patients are considered a contributing factor to Type 2 Diabetes (T2D). Exposure to high lipids initially causes the beta-cells to expand in population. Long-term exposure t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0dbcfcfa60daba7f20c2d27eba953e89
https://doi.org/10.1101/2020.08.11.247452
https://doi.org/10.1101/2020.08.11.247452
AKT1 Regulates Endoplasmic Reticulum Stress and Mediates the Adaptive Response of Pancreatic β Cells
Autor:
Bangyan L. Stiles, Eileen X. Stiles, Jingyu Chen, Ni Zeng, Zhechu Peng, Lina He, Richa Aggarwal, Chien-Yu Chen, Anketse Debebe
Publikováno v:
Mol Cell Biol
Isoforms of protein kinase B (also known as AKT) play important roles in mediating insulin and growth factor signals. Previous studies have suggested that the AKT2 isoform is critical for insulin-regulated glucose metabolism, while the role of the AK
Autor:
Jingyu Chen, M. Wang, T. Dong, Jen-Ming Huang, W. Yuan, Vivian Medina, Deborah L. Johnson, Bangyan L. Stiles, S. Atkins, Ni Zeng, Lina He, I. M. Mahajan, K. Machida, C. Y. Chen, Meng Li, Zhechu Peng, Michael Kahn, Anketse Debebe, K. R. Aggarwal, B. W. Stiles, D. Fu, Zea Borok, Changqing Ju, Chien-Yu Chen, C. Jia
Publikováno v:
Oncogene
Obesity confers an independent risk for carcinogenesis. In the liver, steatosis often proceeds cancer formation; however, the mechanisms by which steatosis promotes carcinogenesis is unknown. We hypothesize that steatosis alters the microenvironment
Autor:
Zhechu Peng, Aggarwal, Richa, Ni Zeng, Lina He, Stiles, Eileen X., Debebe, Anketse, Jingyu Chen, Chien-Yu Chen, Stiles, Bangyan L.
Publikováno v:
Molecular & Cellular Biology; Jun2020, Vol. 40 Issue 11, p1-37, 37p
Autor:
Carl B. Rountree, Vivian Medina, Kinji Asahina, James Gubbins, Fan Fei, Lina He, Bangyan L. Stiles, Michael Kahn, Jiaohong Wang, Zhechu Peng
Publikováno v:
Fibrogenesis & Tissue Repair
Background Hepatic fibrosis is a prominent pathological feature associated with chronic liver disease including non-alcoholic hepatosteatosis (NASH), and a precursor for liver cancer development. We previously reported that PTEN loss in the liver, wh
Publikováno v:
Pancreas. 44(7)
In injury conditions, myofibroblasts are induced to lay down matrix proteins and support the repair process. In this study, we investigated the role of myofibroblasts, particularly stellate cells, in the growth and regeneration of pancreatic β cells
Autor:
Bangyan L. Stiles, Zhenrong Shi, Kai-Ting Yang, Ni Zeng, Vivian Medina, Richa Aggarwal, Zhechu Peng, Zhiou Luo, Jennifer-Ann Bayan, Keerthi Boddupally, Melissa Kim, Anketse Kassa, Lina He
Aims/hypothesis Adult beta cells have a diminished ability to proliferate. Phosphatase and tensin homologue (PTEN) is a lipid phosphatase that antagonises the function of the mitogenic phosphatidylinositol 3-kinase (PI3K) pathway. The objective of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d65104a512157d5e48c4f1c09692b55
https://europepmc.org/articles/PMC3918745/
https://europepmc.org/articles/PMC3918745/
Autor:
Lina He, Gubbins, James, Zhechu Peng, Medina, Vivian, Fan Fei, Kinji Asahina, Jiaohong Wang, Kahn, Michael, Rountree, Carl B., Stiles, Bangyan L.
Publikováno v:
Fibrogenesis & Tissue Repair; 6/14/2016, Vol. 9, p1-13, 13p, 1 Color Photograph, 8 Graphs