Underlying Genes and Molecular Mechanism of Keloids Investigated by Integrated Bioinformatics Analysis

Autor: Zhe-Hu Jin, Mei-Tong Jin, chuying Li, Yin-Li Luo, Long-Quan Pi

Background: We aimed to identify the overlapping differentially expressed genes (DEGs) of keloids distinguished from normal scar and normal skin and relevant underlying mechanism using integrated bioinformatics methods.Methods: The expression profile

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2a400e7d32b534408c7481d1a3a4058d
https://doi.org/10.21203/rs.3.rs-148691/v1

Vasoactive intestinal peptide stimulates melanogenesis in B16F10 mouse melanoma cells via CREB/MITF/tyrosinase signaling

Autor: Xing Hua Yuan, Chi Hyun Park, Jang Hee Oh, Dong Hun Lee, Yu Dan Tian, Mira Han, Jin Ho Chung, Zhe Hu Jin, Ji-Eun Kim, Cheng Yao

Publikováno v: Biochemical and Biophysical Research Communications. 477:336-342

Vasoactive intestinal peptide (VIP), one of the major skin neuropeptides, has been suggested to have active roles in the pathogenesis of inflammatory skin disorders such as atopic dermatitis and psoriasis, which can commonly cause post-inflammatory h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d8e8748e8658ad3dc6ed52e17042af3
https://doi.org/10.1016/j.bbrc.2016.06.105

UV irradiation-induced production of monoglycosylated biglycan through downregulation of xylosyltransferase 1 in cultured human dermal fibroblasts

Autor: Min Kyeong Shin, Zhe Hu Jin, Cheng Long Jin, Chi-Hyun Park, Cheng Yao, Jang Hee Oh, Mira Han, Jin Ho Chung

Publikováno v: Journal of Dermatological Science. 79:20-29

Background Biglycan (BGN) is a proteoglycan composed of a 42-kDa core protein and two glycosaminoglycan (GAG) chains, and known to be involved in structural, space-filling functions and many physiological regulations in the skin. Objective To investi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05aaef83927c27ad5c5b485fdf1f7589
https://doi.org/10.1016/j.jdermsci.2015.03.018

Improved anti-tumor efficiency against prostate cancer by docetaxel-loaded PEG-PCL micelles

Autor: Xue-Zhe Yin, Zhong-Gao Gao, Tie-xiong Jin, Sheng-jun Piao, Zhe-hu Jin, Ming-ji Jin

Publikováno v: Journal of Huazhong University of Science and Technology [Medical Sciences]. 34:66-75

This study primarily focused on the systematic assessment of both in vitro and in vivo anti-tumor effects of docetaxel-loaded polyethylene glycol (PEG)2000-polycaprolactone (PCL)2600 micelles on hormone-refractory prostate cancer (HRPC). By using sol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::518343421517a5a15860f9f8a8b5af99
https://doi.org/10.1007/s11596-014-1233-0

ROS and endothelial nitric oxide synthase (eNOS)-dependent trafficking of angiotensin II type 2 receptor begets neuronal NOS in cardiac myocytes

Autor: Ju Hong Jeon, Ji Hyun Jang, Yin Hua Zhang, Shigeo Godo, Hiroaki Shimokawa, Guangyu Wu, Chun Zi Jin, Jung Nyeo Chun, Sung Joon Kim, Zhe Hu Jin

Publikováno v: Jang, J H, Chun, J H, Godo, S, Wu, G, Shimokawa, H, Jin, C Z, Jeon, J H, Kim, S J, Jin, Z H & Zhang, Y H 2015, ' ROS and endothelial nitric oxide synthase (eNOS)-dependent trafficking of angiotensin II type 2 receptor begets neuronal NOS in cardiac myocytes ', Basic Research in Cardiology, vol. 110, no. 21 . https://doi.org/10.1007/s00395-015-0477-6

Angiotensin II (Ang II), a potent precursor of hypertrophy and heart failure, upregulates neuronal nitric oxide synthase (nNOS or NOS1) in the myocardium. Here, we investigate the involvement of type 1 and 2 angiotensin receptors (AT1R and AT2R) and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc6376518600196cfa16852267e1f70b
https://www.research.manchester.ac.uk/portal/en/publications/ros-and-endothelial-nitric-oxide-synthase-enosdependent-trafficking-of-angiotensin-ii-type-2-receptor-begets-neuronal-nos-in-cardiac-myocytes(2cd47fc6-56b1-42fe-aa5c-c85dd0ae6144).html