Zobrazeno 1 - 10
of 206
pro vyhledávání: '"Zhe‐Xiong Lian"'
Autor:
Min Ma, Liang Li, Shu-Han Yang, Chuan Huang, Weitao Zhuang, Shujie Huang, Xin Xia, Yong Tang, Zijun Li, Zhi-Bin Zhao, Qingyun Chen, Guibin Qiao, Zhe-Xiong Lian
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Regulatory T (Treg) cells are critical in shaping an immunosuppressive microenvironment to favor tumor progression and resistance to therapies. However, the heterogeneity and function of Treg cells in esophageal squamous cell carcinoma (ESCC) remain
Externí odkaz:
https://doaj.org/article/f5ed722987764aa5a7ce1a11d994c17c
Autor:
Hao-Xian Zhu, Shu-Han Yang, Cai-Yue Gao, Zhen-Hua Bian, Xiao-Min Chen, Rong-Rong Huang, Qian-Li Meng, Xin Li, Haosheng Jin, Koichi Tsuneyama, Ying Han, Liang Li, Zhi-Bin Zhao, M. Eric Gershwin, Zhe-Xiong Lian
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Primary biliary cholangitis (PBC) is a cholestatic autoimmune liver disease characterized by autoreactive T cell response against intrahepatic small bile ducts. Here, we use Il12b-/-Il2ra-/- mice (DKO mice) as a model of autoimmune cholangit
Externí odkaz:
https://doaj.org/article/a3208583c2fb4b3fbee865627da0c7c2
Autor:
Kai Yan, Qing‐Zhi Liu, Rong‐Rong Huang, Yi‐Hua Jiang, Zhen‐Hua Bian, Si‐Jin Li, Liang Li, Fei Shen, Koichi Tsuneyama, Qing‐Ling Zhang, Zhe‐Xiong Lian, Haixia Guan, Bo Xu
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 3, Pp n/a-n/a (2024)
Abstract Background Papillary thyroid carcinoma (PTC) is the most common malignant endocrine tumour, and its incidence and prevalence are increasing considerably. Cellular heterogeneity in the tumour microenvironment is important for PTC prognosis. S
Externí odkaz:
https://doaj.org/article/0886b8d5b2024dc7a888c18f3cbb4525
Publikováno v:
Medicine Advances, Vol 1, Iss 2, Pp 97-114 (2023)
Abstract Autoimmune liver diseases (ALDs) are chronic inflammatory hepatobiliary diseases in which the autoimmune responses directed against liver tissue result in inflammation and tissue damage. There are several types of ALDs, including autoimmune
Externí odkaz:
https://doaj.org/article/2780f1a59ad043179553961b0d514f47
Autor:
Fei Wang, Chuan Huang, Jie Long, Zhi-Bin Zhao, Hai-Qing Ma, Xue-Qing Yao, Liang Li, Zhe-Xiong Lian
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background The Notch signaling mutation is associated with enhanced anti-tumor immune response in colorectal cancer (CRC). In this study, we aim to investigate the underlying mechanism and the predictive potential of Notch signaling mutation
Externí odkaz:
https://doaj.org/article/d5c2699f83534ef2ab5a785254e98486
Autor:
Ting Xu, Hao-Xian Zhu, Xing You, Jin-Fen Ma, Xin Li, Pan-Yue Luo, Yang Li, Zhe-Xiong Lian, Cai-Yue Gao
Publikováno v:
JCI Insight, Vol 8, Iss 8 (2023)
Primary Sjögren’s syndrome (pSS) is a systemic autoimmune inflammatory disease mainly defined by T cell–dominated destruction of exocrine glands. Currently, CD8+ T cells are thought to be involved in the pathogenesis of pSS. However, the single-
Externí odkaz:
https://doaj.org/article/e9e2744286fa44a1888d8ef78dbad7dd
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-22 (2022)
Abstract Background Finding correlation patterns is an important goal of analyzing biological data. Currently available methods for correlation analysis mainly use non-direct associations, such as the Pearson correlation coefficient, and focus on the
Externí odkaz:
https://doaj.org/article/6fb76e2382c04aa0be5b4fe3dff0a666
Autor:
Ren-Dong Hu, Wen Zhang, Liang Li, Zu-Qi Zuo, Min Ma, Jin-Fen Ma, Ting-Ting Yin, Cai-Yue Gao, Shu-Han Yang, Zhi-Bin Zhao, Zi-Jun Li, Gui-Bin Qiao, Zhe-Xiong Lian, Kun Qu
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-11 (2021)
Abstract Activation of adipose tissue macrophages (ATMs) contributes to chronic inflammation and insulin resistance in obesity. However, the transcriptional regulatory machinery involved in ATM activation during the development of obesity is not full
Externí odkaz:
https://doaj.org/article/ad58d1f293f74a799216e28a046493be
Autor:
Zhen Chen, Meng-Li Guo, Ya-Yi Li, Kai Yan, Liang Li, Fei Shen, Haixia Guan, Qing-Zhi Liu, Bo Xu, Zhe-Xiong Lian
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundThyroid tissue has a special immune microenvironment that is not well characterized. Whether immune cells have a prognostic value in the recurrence of papillary thyroid cancer (PTC) needs further investigation.MethodsMultinodular non-toxic
Externí odkaz:
https://doaj.org/article/28b06000ee0f4779b629ca70c2d3d47f
Autor:
Wanshan Du, Cai-Yue Gao, Xing You, Liang Li, Zhi-Bin Zhao, Mengting Fang, Zhiming Ye, Meijun Si, Zhe-Xiong Lian, Xueqing Yu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IgA nephropathy (IgAN) is the most common primary glomerulonephritis, characterized by glomerular deposition of IgA immune complexes, mainly produced by B cells under the regulation of CD4+T cells. However, the alterations of specific CD4+T cell subs
Externí odkaz:
https://doaj.org/article/6f0c37540c0945dc8283aa4b81456e87