Zobrazeno 1 - 10
of 228
pro vyhledávání: '"Zhaozhong Zhu"'
Autor:
Tadao Ooka, Naoto Usuyama, Ryohei Shibata, Michihito Kyo, Jonathan M. Mansbach, Zhaozhong Zhu, Carlos A. Camargo, Kohei Hasegawa
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract Bronchiolitis is the leading cause of infant hospitalization. However, the molecular networks driving bronchiolitis pathobiology remain unknown. Integrative molecular networks, including the transcriptome and metabolome, can identify functio
Externí odkaz:
https://doaj.org/article/a60cd1bfee81445b891b00d97fa785e2
Autor:
Carlos A Camargo, Kohei Hasegawa, Zhaozhong Zhu, Tadao Ooka, Andrea Hahn, Marcos Pérez-Losada, Jonathan M Mansbach, Michihito Kyo, Ryohei Shibata, Brennan Harmon
Publikováno v:
BMJ Open Respiratory Research, Vol 11, Iss 1 (2024)
Background Respiratory syncytial virus (RSV) bronchiolitis contributes to a large morbidity and mortality burden globally. While emerging evidence suggests that airway microRNA (miRNA) is involved in the pathobiology of RSV infection, its role in the
Externí odkaz:
https://doaj.org/article/a48ababf8e1e4fb8a4a6bd2b9f8ad43d
Autor:
Kylie I. Krohmaly, Marcos Perez-Losada, Ignacio Ramos-Tapia, Zhaozhong Zhu, Kohei Hasegawa, Carlos A. Camargo Jr., Brennan Harmon, Janice A. Espinola, Laura Reck Cechinel, Rachael Batabyal, Robert J. Freishtat, Andrea Hahn
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Bronchiolitis, a viral lower respiratory infection, is the leading cause of infant hospitalization, which is associated with an increased risk for developing asthma later in life. Bronchiolitis can be caused by several respiratory viruses, such as re
Externí odkaz:
https://doaj.org/article/27364db397f7401ebc349439a851298c
Autor:
Zhaozhong Zhu, Yijun Li, Robert J. Freishtat, Juan C. Celedón, Janice A. Espinola, Brennan Harmon, Andrea Hahn, Carlos A. Camargo, Liming Liang, Kohei Hasegawa
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Bronchiolitis is the most common lower respiratory infection in infants, yet its pathobiology remains unclear. Here we present blood DNA methylation data from 625 infants hospitalized with bronchiolitis in a 17-center prospective study, and
Externí odkaz:
https://doaj.org/article/3fa02ad0977a4a968bb8333fd7819fee
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 22 (2023)
Background Patients with rheumatoid arthritis (RA) have a 2‐ to 10‐fold increased risk of cardiovascular disease (CVD), but the biological mechanisms and existence of causality underlying such associations remain to be investigated. We aimed to i
Externí odkaz:
https://doaj.org/article/e0047ccbb35941eba1abbbf3f30b8018
Autor:
Zhaozhong Zhu, Ruina You, Huiru Li, Shuidong Feng, Huan Ma, Chaohao Tuo, Xiangxian Meng, Song Feng, Yousong Peng
Publikováno v:
PeerJ, Vol 11, p e16194 (2023)
Influenza viruses pose a significant and ongoing threat to human health. Many host factors have been identified to be associated with influenza virus infection. However, there is currently a lack of an integrated resource for these host factors. This
Externí odkaz:
https://doaj.org/article/cf3f8e8f29854448b8c9b259ffd110e3
Autor:
Ryohei Shibata, Zhaozhong Zhu, Michihito Kyo, Tadao Ooka, Robert J. Freishtat, Jonathan M. Mansbach, Marcos Pérez-Losada, Carlos A. Camargo, Jr., Kohei Hasegawa
Publikováno v:
EBioMedicine, Vol 95, Iss , Pp 104742- (2023)
Summary: Background: Bronchiolitis is a leading cause of infant hospitalization. Recent research suggests the heterogeneity within bronchiolitis and the relationship of airway viruses and bacteria with bronchiolitis severity. However, little is known
Externí odkaz:
https://doaj.org/article/e87c8fd0a5384e46a8b566686d929375
Autor:
Zhaozhong Zhu, Shengqiang Ge, Zena Cai, Yifan Wu, Congyu Lu, Zheng Zhang, Ping Fu, Longfei Mao, Xiaodong Wu, Yousong Peng
Publikováno v:
Veterinary Research, Vol 53, Iss 1, Pp 1-11 (2022)
Abstract African swine fever virus (ASFV) is a large DNA virus that infects domestic pigs with high morbidity and mortality rates. Repeat sequences, which are DNA sequence elements that are repeated more than twice in the genome, play an important ro
Externí odkaz:
https://doaj.org/article/a7c17599dd144248b49776601ffe9af7
Autor:
Xikun Han, Zhaozhong Zhu, Qian Xiao, Jun Li, Xiumei Hong, Xiaobin Wang, Kohei Hasegawa, Carlos A. Camargo, Liming Liang
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
A comprehensive genetic analysis of the relationship between childhood obesity and childhood asthma identifies shared mechanisms and potential mediators linking the two pediatric disorders.
Externí odkaz:
https://doaj.org/article/bbe3ecd484d545ce9690dbf74d3b98ce
Autor:
Michimasa Fujiogi, Yoshihiko Raita, Marcos Pérez-Losada, Robert J. Freishtat, Juan C. Celedón, Jonathan M. Mansbach, Pedro A. Piedra, Zhaozhong Zhu, Carlos A. Camargo, Kohei Hasegawa
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Bronchiolitis is major cause of infection, morbidity and hospitalisation. Here the authors apply transcriptomic based assessment of the host response, microbiome composition and function, and associate this to bronchiolitis severity.
Externí odkaz:
https://doaj.org/article/eb3de97ea67e48ba9b6b652ed2a65779