Decreased Retinal Vascular Density in Alzheimer’s Disease (AD) and Mild Cognitive Impairment (MCI): An Optical Coherence Tomography Angiography (OCTA) Study

Autor: Xi Wang, Qianhua Zhao, Rui Tao, Huimeng Lu, Zhenxu Xiao, Li Zheng, Ding Ding, Saineng Ding, Yichen Ma, Zhaozeng Lu, Yiqin Xiao

Publikováno v: Frontiers in Aging Neuroscience, Vol 12 (2021)

BackgroundTo explore the retinal vascular density changes in Alzheimer’s disease (AD) and mild cognitive impairment (MCI) patients using optical coherence tomography angiography (OCTA).MethodsWe recruit 62 AD patients, 47 MCI patients, and 49 cogni

Externí odkaz: https://doaj.org/article/b9bda3aee9fa46bea4305efa4056eba6

TGF

Autor: Shuhao, Fu, Zhaozeng, Lu, Wen, Ye

Publikováno v: Evidence-based complementary and alternative medicine : eCAM. 2022

To assess Interlukin-11 (IL11) expression in the tears of patients after filtration surgery and to find out its pro-transdifferentiational and pro-fibrotic functions and mechanisms on subconjunctival human Tenon's capsule fibroblasts (HTFs) induced b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d6d051aa7fe360e3a6f3bddb644757e7
https://pubmed.ncbi.nlm.nih.gov/35865343

Increased Risk of Ocular Hypertension in Patients with Cushing’s Disease: An Underestimated Comorbidity

Autor: Zhengyuan Chen, Yichen Ma, Zengyi Ma, Zhao Ye, Wenqiang He, Qilin Zhang, Min He, Hongying Ye, Zhaoyun Zhang, Yongfei Wang, Huiyin Yang, Zhaozeng Lu, Zhiliang Wang, Nidan Qiao, Yiqin Xiao, Yao Zhao

BackgroundThe association between ocular hypertension and endogenous hypercortisolemia, as well as the ophthalmological outcomes after endocrine remission due to a surgical resection were still unknown. MethodsIntraocular pressure (IOP), visual field

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c23da9c929021b9814180258036bfd9d
https://doi.org/10.21203/rs.3.rs-64004/v1

Perifovea retinal thickness as an ophthalmic biomarker for mild cognitive impairment and early Alzheimer's disease

Autor: Yiqin Xiao, Ding Ding, Zhaozeng Lu, Li Zheng, Zhen Hong, Xiaoniu Liang, Shuhao Fu, Qianhua Zhao, Rui Tao

Publikováno v: Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 405-414 (2019)

Introduction The aim of this study was to investigate retinal thickness as a biomarker for identifying patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD). Methods The retinal thickness, utilizing the spectral domain optical co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb6a004faaafaa67afb6a45907f69f40
https://pubmed.ncbi.nlm.nih.gov/31206006

Angiotensin II as a Morphogenic Cytokine Stimulating Fibrogenesis of Human Tenon's Capsule Fibroblasts

Autor: Huimin Shi, Yiqin Xiao, Zhaozeng Lu, Yuyan Zhang, Shuhao Fu, Wen Ye

Publikováno v: Investigative Ophthalmology & Visual Science. 56:855-864

PURPOSE: To examine the expression of Angiotensin II (Ang II) and its type I, and type II receptors (AT1R, AT2R) in rabbit Tenon's capsule fibroblasts after trabeculectomy, and to investigate the effects of Ang II on cultured human Tenon's capsule fi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8ddb74c60241ced7ca9b48aa86dc349
https://doi.org/10.1167/iovs.14-15301