Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Zhaoyuan Fang"'
Autor:
Ying Jin, Yuefeng Wu, Alexandre Reuben, Liang Zhu, Carl M. Gay, Qingzhe Wu, Xintong Zhou, Haomin Mo, Qi Zheng, Junyu Ren, Zhaoyuan Fang, Teng Peng, Nan Wang, Liang Ma, Lungevity PANSHI Initiative Consortium, Yun Fan, Hai Song, Jianjun Zhang, Ming Chen
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-19 (2024)
Abstract Small cell lung cancer (SCLC) is an aggressive pulmonary neuroendocrine malignancy featured by cold tumor immune microenvironment (TIME), limited benefit from immunotherapy, and poor survival. The spatial heterogeneity of TIME significantly
Externí odkaz:
https://doaj.org/article/13c7204465ef49f6b7c5296892d33b0a
Autor:
Zhaoyuan Fang, Xiangkun Han, Yueqing Chen, Xinyuan Tong, Yun Xue, Shun Yao, Shijie Tang, Yunjian Pan, Yihua Sun, Xue Wang, Yujuan Jin, Haiquan Chen, Liang Hu, Lijian Hui, Lin Li, Luonan Chen, Hongbin Ji
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-14 (2023)
Abstract Lkb1 deficiency confers the Kras-mutant lung cancer with strong plasticity and the potential for adeno-to-squamous transdifferentiation (AST). However, it remains largely unknown how Lkb1 deficiency dynamically regulates AST. Using the class
Externí odkaz:
https://doaj.org/article/1de59c754db845e4b4f94de55da2e5fb
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/8ad208a18877453bb38f43de9bebcfdf
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 19, Iss 2, Pp 319-329 (2021)
The rapid advancement of single-cell technologies has shed new light on the complex mechanisms of cellular heterogeneity. However, compared to bulk RNA sequencing (RNA-seq), single-cell RNA-seq (scRNA-seq) suffers from higher noise and lower coverage
Externí odkaz:
https://doaj.org/article/0204d71c39c3498098aeb49775987852
Autor:
Zuoyun Wang, Zhaoyuan Fang, Gaobin Chen, Bo Liu, Jinjin Xu, Fei Li, Fuming Li, Hongyan Liu, Haoen Zhang, Yihua Sun, Gang Tian, Haiquan Chen, Guoliang Xu, Lei Zhang, Liang Hu, Hongbin Ji
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 2, Pp 222-233 (2021)
Chromobox 4 (CBX4) is a core component of polycomb-repressive complex 1 with important roles in cancer biology and tissue homeostasis. Aberrant expression of CBX4 has been implicated in several human malignancies. However, its role and underlying mec
Externí odkaz:
https://doaj.org/article/d506f5673023447b8fcc6c3d636ed97e
Autor:
Yabin Chen, Zhaoyuan Fang, Ying Tang, Yujuan Jin, Chenchen Guo, Liang Hu, Yang Xu, Xidong Ma, Jie Gao, Mei Xie, Xuelei Zang, Sanhong Liu, Haiquan Chen, Roman K. Thomas, Xinying Xue, Hongbin Ji, Luonan Chen
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 12, Pp n/a-n/a (2021)
Externí odkaz:
https://doaj.org/article/07e78d2f8427412bbc73872b3fd5aa3f
Autor:
Lei Chen, Xianchao Zhou, Tao Zeng, Xiaoyong Pan, Yu-Hang Zhang, Tao Huang, Zhaoyuan Fang, Yu-Dong Cai
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Cancer has been generally defined as a cluster of systematic malignant pathogenesis involving abnormal cell growth. Genetic mutations derived from environmental factors and inherited genetics trigger the initiation and progression of cancers. Althoug
Externí odkaz:
https://doaj.org/article/2e7692036a414855b5a38291434a5544
Autor:
Xiangkun Han, Fuming Li, Zhaoyuan Fang, Yijun Gao, Fei Li, Rong Fang, Shun Yao, Yihua Sun, Li Li, Wenjing Zhang, Huimin Ma, Qian Xiao, Gaoxiang Ge, Jing Fang, Hongda Wang, Lei Zhang, Kwok-kin Wong, Haiquan Chen, Yingyong Hou, Hongbin Ji
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/cf4a9ccec2fe4b9f8ab94dff36b82a13
Autor:
Yiyu Lu, Zhaoyuan Fang, Tao Zeng, Meiyi Li, Qilong Chen, Hui Zhang, Qianmei Zhou, Yiyang Hu, Luonan Chen, Shibing Su
Publikováno v:
Chinese Medicine, Vol 14, Iss 1, Pp 1-13 (2019)
Abstract Background In traditional Chinese medicine (TCM) clinical practice, TCM syndromes help to understand human homeostasis and guide individualized treatment. However, the TCM syndrome changes with disease progression, of which the scientific ba
Externí odkaz:
https://doaj.org/article/af8b19bcfefd46d492053fb1e8f84022
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-13 (2018)
Abstract Background Lung cancer is a very heterogeneous disease that can be pathologically classified into different subtypes including small-cell lung carcinoma (SCLC), lung adenocarcinoma (LUAD), lung squamous cell carcinoma (LUSC) and large-cell c
Externí odkaz:
https://doaj.org/article/d51871e803ca42a7b242aa32e8a3d1c3