Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Zhaoyong Yang"'
Autor:
Shuai Fan, Xudong Lü, Xiyu Wei, Ruijie Lü, Cuiyue Feng, Yuanyuan Jin, Maocai Yan, Zhaoyong Yang
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 982-989 (2024)
The thermostable α-amylase derived from Bacillus licheniformis (BLA) has multiple advantages, including enhancing the mass transfer rate and by reducing microbial contamination in starch hydrolysis. Nonetheless, the application of BLA is constrained
Externí odkaz:
https://doaj.org/article/7fe0422e3d7049299776bbdb0b5be890
Publikováno v:
SAGE Open Medical Case Reports, Vol 12 (2024)
Nature killer cell therapy has shown strong efficacy in the field of oncology in recent years and has been applied to patients with metastases with the aim of improving the prognosis of advanced gastric cancer. A 59-year-old male with gastric adenoca
Externí odkaz:
https://doaj.org/article/5113b243912c490fb9e93b9aa6f2dedf
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 6 (2022)
ABSTRACT Phosphopantetheinyl transferases (PPTases) play important roles in activating apo-acyl carrier proteins (apo-ACPs) and apo-peptidyl carrier proteins (apo-PCPs) in both primary and secondary metabolism. PPTases catalyze the posttranslational
Externí odkaz:
https://doaj.org/article/df58a8b3b7f74a21a2b96c87d3affeee
Autor:
Xudong Lü, Cuiyue Feng, Ruijie Lü, Xiyu Wei, Shuai Fan, Maocai Yan, Xiandui Zhu, Zhifei Zhang, Zhaoyong Yang
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Emergence of the SARS-CoV-2 Omicron variant of concern (VOC; B.1.1.529) resulted in a new peak of the COVID-19 pandemic, which called for development of effective therapeutics against the Omicron VOC. The receptor binding domain (RBD) of the spike pr
Externí odkaz:
https://doaj.org/article/60412b4cc2f44d4f9347e83eed52930d
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 55 (2022)
Recombinant human peroxiredoxin-5 (hPRDX5), isolated from anti-cancer bioactive peptide (ACBPs), shows a homology of 89% with goat peroxiredoxin-5 (gPRDX5) and is reported to display anti-tumor activity in vivo. Herein, we explored the effect of hPRD
Externí odkaz:
https://doaj.org/article/be13ba6840f34c78b448c0b383515b2a
Publikováno v:
Data in Brief, Vol 25, Iss , Pp - (2019)
Maleimide ring is an important scaffold in organic chemistry, and tosyloxy group is a functional group widely used in organic synthesis. Nevertheless, tosyloxymaleimide compounds have been rarely reported, and the reactivity properties and potential
Externí odkaz:
https://doaj.org/article/2bf46167778740e4a43a0622c6dea376
Autor:
Shuai Fan, Danyang Li, Maocai Yan, Xiao Feng, Guangxin Lv, Guangteng Wu, Yuanyuan Jin, Yucheng Wang, Zhaoyong Yang
Publikováno v:
Molecules, Vol 26, Iss 5, p 1451 (2021)
New drugs with novel antibacterial targets for Gram-negative bacterial pathogens are desperately needed. The protein LpxC is a vital enzyme for the biosynthesis of lipid A, an outer membrane component of Gram-negative bacterial pathogens. The ACHN-97
Externí odkaz:
https://doaj.org/article/456bd508e3cb4b058fecb275172cc5de
Autor:
Maocai Yan, Zhen Zhang, Zhaoming Liu, Chunyan Zhang, Jingchang Zhang, Shuai Fan, Zhaoyong Yang
Publikováno v:
Molecules, Vol 24, Iss 22, p 4057 (2019)
Human carboxylesterase 1 (hCES1) is a major carboxylesterase in the human body and plays important roles in the metabolism of a wide variety of substances, including lipids and drugs, and therefore is attracting more and more attention from areas inc
Externí odkaz:
https://doaj.org/article/c8c8819f56b943878875a197440d0801
Publikováno v:
Molecules, Vol 24, Iss 3, p 433 (2019)
Mycobacterium tuberculosis (Mtb) has recently surpassed HIV/AIDS as the leading cause of death by a single infectious agent. The standard therapeutic regimen against tuberculosis (TB) remains a long, expensive process involving a multidrug regimen, a
Externí odkaz:
https://doaj.org/article/f34ca6fa4e924f8dbeb584657ce2a914
Publikováno v:
Chemical Science. 13:7581-7586
A robotic workflow for directed evolution of new enzymatic activities via high-throughput library creation and label-free MS screening.