Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Zhaoxuan Yang"'
Publikováno v:
RSC Chemical Biology. 3:853-858
Herein we report a dual-responsive doxorubicin-indoximod conjugate (DOXIND) for programmed chemoimmunotherapy. This conjugate is able to release doxorubicin and indoximod upon exposure to appropriate stimuli for synergistic chemotherapy and immunothe
Autor:
Jinhao Gao, Dongxia Chen, Hongyu Lin, Ao Li, Xing Liu, Xiangjie Luo, Zhaoxuan Yang, Lijiao Yang, Lingxuan Li
Publikováno v:
Analytical Chemistry. 93:16552-16561
In vivo levels of reactive oxygen species (ROS) and reactive nitrogen species (RNS) are critical to many physiological and pathological processes. Because of the distinct differences in their biological generation and effects, simultaneously visualiz
Autor:
Jinhao Gao, Xiaoyuan Chen, Yifan Fan, Hongyu Lin, Kun Liu, Chengjie Sun, Xiangjie Luo, Ao Li, Bilun Kang, Zhaoxuan Yang
Publikováno v:
ACS Nano. 15:17831-17841
GSH-mediated liver biotransformation is a crucial physiological process demanding efficient research tools. Here, we report a type of amorphous FexMnyO nanoparticles (AFMO-ZDS NPs) as redox-activated probes for in vivo visualization of the dynamics o
Publikováno v:
ACS chemical biology. 17(4)
The limited therapeutic effects of immunotherapy for most types of cancer stimulates the pursuit for efficient methods to improve its response rate. Herein we report the design and synthesis of a cascade-responsive molecular prodrug for tandem chemoi
Autor:
Ao, Li, Xiangjie, Luo, Lingxuan, Li, Dongxia, Chen, Xing, Liu, Zhaoxuan, Yang, Lijiao, Yang, Jinhao, Gao, Hongyu, Lin
Publikováno v:
Analytical chemistry. 93(49)
Autor:
Kun, Liu, Bilun, Kang, Xiangjie, Luo, Zhaoxuan, Yang, Chengjie, Sun, Ao, Li, Yifan, Fan, Xiaoyuan, Chen, Jinhao, Gao, Hongyu, Lin
Publikováno v:
ACS nano. 15(11)
GSH-mediated liver biotransformation is a crucial physiological process demanding efficient research tools. Here, we report a type of amorphous Fe
Autor:
Jiaqi Huang, Hongyu Lin, Zhaoxuan Yang, Hong Shan, Jingyu Xin, Jinhao Gao, Ke Zhang, Xiangjie Luo, Xuanqing Gong
Publikováno v:
Biomaterials Science. 7:262-271
Cisplatin (CDDP) and arsenic trioxide (ATO), two representative inorganic anticancer drugs, have been successful in the treatment against several kinds of malignancies. However, combination therapy with these two drugs in clinical application suffers
Publikováno v:
Cell Reports Physical Science. 3:100950
Autor:
Chengjie Sun, Zhaoxuan Yang, Peng Wu, Xiangjie Luo, Kun Liu, Binju Wang, Hongyu Lin, Jinhao Gao
Publikováno v:
Cell Reports Physical Science. 3:100920
Publikováno v:
Angewandte Chemie (International ed. in English). 60(3)
Despite widespread applications for cancer treatment, chemotherapy is restricted by several limitations, including low targeting specificity, acquired drug resistance, and concomitant adverse side effects. It remains challenging to overcome these dra