Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Zhaorui Ren"'
Autor:
Guanheng Yang, Wansheng Shi, Xingyin Hu, Jingzhi Zhang, Zhijuan Gong, Xinbing Guo, Zhaorui Ren, Fanyi Zeng
Publikováno v:
Haematologica, Vol 99, Iss 8 (2014)
Although β-thalassemia is one of the most common human genetic diseases, there is still no effective treatment other than bone marrow transplantation. Induced pluripotent stem cells have been considered good candidates for the future repair or repla
Externí odkaz:
https://doaj.org/article/e07b98f632e3408ab653df0eda283a6c
Autor:
Wei Li, Shuyang Xie, Xinbing Guo, Xiuli Gong, Shu Wang, Dan Lin, Jingzhi Zhang, Zhaorui Ren, Shuzhen Huang, Fanyi Zeng, Yitao Zeng
Publikováno v:
Haematologica, Vol 93, Iss 3 (2008)
Background β-thalassemia is one of the most common genetic diseases in the world and requires extensive therapy. Lentiviral-mediated gene therapy has been successfully exploited in the treatment of β-thalassemia and showed promise in clinical appli
Externí odkaz:
https://doaj.org/article/ef0aea4b1c4843baa909b337494631f4
Publikováno v:
Molecules and Cells. 46:219-230
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70278e993c689a6a0741a3b54fa71ac5
https://doi.org/10.14348/molcells.2023.2095
https://doi.org/10.14348/molcells.2023.2095
Publikováno v:
Experimental and Therapeutic Medicine
Down syndrome (DS), caused by the trisomy of chromosome 21, is one of the common chromosomal disorders, the main clinical manifestations of which are delayed nervous development and intellectual disability. Long non-coding RNAs (lncRNAs) have critica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5abc0c68527fc69e85385f53a2d02843
https://doi.org/10.3892/etm.2021.10133
https://doi.org/10.3892/etm.2021.10133
Publikováno v:
Journal of Physics: Conference Series. 2093:012035
In the process of site selection for the deployment of distributed systems, in order to solve the problem of inaccurate spatial isolation simulation results caused by the large influence of complex geographic information such as terrain and weather o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fe0883459572d50f0623f786f06ea09
https://doi.org/10.1088/1742-6596/2093/1/012035
https://doi.org/10.1088/1742-6596/2093/1/012035
Publikováno v:
Journal of Physics: Conference Series. 1920:012013
This paper proposes to model and simulate radiation sources in complex electromagnetic environments in space from three aspects of real-time, dynamic and parameter completeness, which solves the problem of fidelity simulation under the high dynamic c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a1ad5a640df675ee802977fd0c71578
https://doi.org/10.1088/1742-6596/1920/1/012013
https://doi.org/10.1088/1742-6596/1920/1/012013
Publikováno v:
The international journal of biochemistrycell biology. 92
Trisomy 21 is the most common chromosomal disorder and underlies Down syndrome. Epigenetics, such as DNA methylation and post-translational histone modifications, plays a vital role in Down syndrome. However, the functions of epigenetics-related long
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f979e4c5c04a7041ee8154daff5cd30
https://pubmed.ncbi.nlm.nih.gov/28965985
https://pubmed.ncbi.nlm.nih.gov/28965985
Publikováno v:
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics. 33(3)
To explore the disease-causing mutations in a patient suspected for giant axonal neuropathy(GAN).Target sequence capture sequencing was used to screen potential mutations in genomic DNA extracted from peripheral blood sample of the patient. Sanger se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::afec950d1d7f752836614e0b4755b840
https://pubmed.ncbi.nlm.nih.gov/27264806
https://pubmed.ncbi.nlm.nih.gov/27264806
Autor:
Juan Wang, Yitao Zeng, Shu-Zhen Huang, Zhaorui Ren, Qingwen Ma, Fanyi Zeng, Shizhong Jiang, Fei Xie
Publikováno v:
DNA and Cell Biology. 31:1335-1340
ΦC31 integrase, a site-specific recombinase, can catalyze integration of circular DNA bearing attB site into pseudo attP sites in mammalian genomes. However, the integration efficiency mediated by integrase is relatively low. Our study centered on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bafcf203b06e812e857b924bb9491341
https://doi.org/10.1089/dna.2011.1590
https://doi.org/10.1089/dna.2011.1590
Publikováno v:
Human Gene Therapy. 21:149-156
Beta-thalassemia is an anemia caused by a relative excess of alpha-hemoglobin (alphaHb) due to absent or reduced beta-hemoglobin (betaHb) synthesis. In this study, we explore whether the introduction of alpha-hemoglobin stabilizing protein (AHSP), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c03544662d7eb713be61005d73f234ab
https://doi.org/10.1089/hum.2009.132
https://doi.org/10.1089/hum.2009.132