Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Zhaoqi Kang"'
Autor:
Dan Xiao, Wen Zhang, Xiaoting Guo, Yidong Liu, Chunxia Hu, Shiting Guo, Zhaoqi Kang, Xianzhi Xu, Cuiqing Ma, Chao Gao, Ping Xu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
d-2-hydroxyglutarate (d-2-HG) is a metabolite that can be aberrantly accumulated and acts as a biomarker in many cancers. Here the authors report a d-2-HG biosensor based on the allosteric transcription factor DhdR which they use for detection in ser
Externí odkaz:
https://doaj.org/article/1248620f2af4490098671ea1ea56cc9b
Autor:
Wensi Meng, Lijie Zhang, Menghao Cao, Yongjia Zhang, Yipeng Zhang, Ping Li, Zhaoqi Kang, Shiting Guo, Ping Xu, Cuiqing Ma, Chao Gao
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-12 (2021)
Abstract Overflow metabolism-caused acetate accumulation is a major problem that restricts industrial applications of various bacteria. 2,3-Butanediol (2,3-BD) synthesis in microorganisms is an ancient metabolic process with unidentified functions. W
Externí odkaz:
https://doaj.org/article/d9d18904b4ea49aab08d5971979dbd20
Autor:
Zhaoqi Kang, Manman Zhang, Kaiyu Gao, Wen Zhang, Wensi Meng, Yidong Liu, Dan Xiao, Shiting Guo, Cuiqing Ma, Chao Gao, Ping Xu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
L-2-hydroxyglutarate (L-2-HG) is an important metabolite but its regulation is poorly understood. Here the authors report an L-2-HG FRET biosensor based on the allosteric transcription factor, LhgR, to monitor L-2-HG in cells and biological samples.
Externí odkaz:
https://doaj.org/article/f6f1f3484bad43509543b1abe04c2573
Autor:
Xianzhi Xu, Rong Xu, Shuang Hou, Zhaoqi Kang, Chuanjuan Lü, Qian Wang, Wen Zhang, Xia Wang, Ping Xu, Chao Gao, Cuiqing Ma
Publikováno v:
Biosensors, Vol 12, Iss 12, p 1111 (2022)
Selective detection of l-lactate levels in foods, clinical, and bacterial fermentation samples has drawn intensive attention. Many fluorescent biosensors based on non-stereoselective recognition elements have been developed for lactate detection. Her
Externí odkaz:
https://doaj.org/article/9cec96f6b67d4396a329b59f4c8ea390
Autor:
Manman Zhang, Chao Gao, Xiaoting Guo, Shiting Guo, Zhaoqi Kang, Dan Xiao, Jinxin Yan, Fei Tao, Wen Zhang, Wenyue Dong, Pan Liu, Chen Yang, Cuiqing Ma, Ping Xu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
It is known that the five carbon platform chemical glutarate can be catabolized by the glutaryl-CoA dehydrogenation pathway. Here, the authors discover an additional glutarate catabolic pathway involving l-2-hydroxyglutarate and show increased glutar
Externí odkaz:
https://doaj.org/article/410d386a718d45bba309100ab02c7216
Autor:
Manman Zhang, Zhaoqi Kang, Xiaoting Guo, Shiting Guo, Dan Xiao, Yidong Liu, Cuiqing Ma, Ping Xu, Chao Gao
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Glutarate, a metabolic intermediate in the catabolism of several amino acids and aromatic compounds, can be catabolized through both the glutarate hydroxylation pathway and the glutaryl-coenzyme A (glutaryl-CoA) dehydrogenation pathway in Ps
Externí odkaz:
https://doaj.org/article/859c880cd71348b2b576a7b894a35865
Autor:
Ping Li, Ping Xu, Yipeng Zhang, Shiting Guo, Zhaoqi Kang, Menghao Cao, Yongjia Zhang, Lijie Zhang, Chao Gao, Wensi Meng, Cuiqing Ma
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-12 (2021)
Cell Discovery
Cell Discovery
Overflow metabolism-caused acetate accumulation is a major problem that restricts industrial applications of various bacteria. 2,3-Butanediol (2,3-BD) synthesis in microorganisms is an ancient metabolic process with unidentified functions. We demonst
Autor:
Shiting Guo, Yidong Liu, Chao Gao, Dan Xiao, Kaiyu Gao, Wen Zhang, Wensi Meng, Ping Xu, Manman Zhang, Zhaoqi Kang, Cuiqing Ma
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
l-2-Hydroxyglutarate (l-2-HG) plays important roles in diverse physiological processes, such as carbon starvation response, tumorigenesis, and hypoxic adaptation. Despite its importance and intensively studied metabolism, regulation of l-2-HG metabol
Autor:
Manman Zhang, Cuiqing Ma, Kaiyu Gao, Zhaoqi Kang, Shiting Guo, Yidong Liu, Dan Xiao, Wen Zhang, Ping Xu, Chao Gao
l-2-Hydroxyglutarate (l-2-HG) plays important roles in diverse physiological processes, such as carbon starvation response, tumorigenesis, and hypoxic adaptation. Despite its importance and intensively studied metabolism, regulation of l-2-HG metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd59850191766b6b5953a54ba7384fe6
https://doi.org/10.1101/2020.07.07.187567
https://doi.org/10.1101/2020.07.07.187567
Publikováno v:
Environmental Microbiology. 20:3927-3940
2,3-Butanediol (2,3-BD) is a primary microbial metabolite that enhances the virulence of Pseudomonas aeruginosa and alters the lung microbiome. 2,3-BD exists in three stereoisomeric forms: (2R,3R)-2,3-BD, meso-2,3-BD and (2S,3S)-2,3-BD. In this study