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Akademický článek

Viola yedoensis Makino alleviates lipopolysaccharide-induced intestinal oxidative stress and inflammatory response by regulating the gut microbiota and NF-κB-NLRP3/ Nrf2-MAPK signaling pathway in broiler

Autor: Haoqiang Zhao, You Huang, Wenjiang Yang, Chunlin Huang, Zhaoping Ou, Jiayu He, Mingqi Yang, Jiao Wu, Huan Yao, Yu Yang, Jine Yi, Li Kong

Publikováno v: Ecotoxicology and Environmental Safety, Vol 282, Iss , Pp 116692- (2024)

Viola yedoensis Makino (Vy) is a well-known traditional Chinese medicine widely used to treat inflammatory diseases. However, the regulatory effects of dietary Vy supplementation on lipopolysaccharide (LPS)-induced intestinal damage in broilers and t

Externí odkaz: https://doaj.org/article/ac0d76804b7a4afb89b6bc33af229e70

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Akademický článek

Betulinic acid attenuates cyclophosphamide-induced intestinal mucosa injury by inhibiting the NF-κB/MAPK signalling pathways and activating the Nrf2 signalling pathway

Autor: Zhaoping Ou, Lijuan Zhu, Chenglong Huang, Chaoyang Ma, Li Kong, Xing Lin, Xinyu Gao, Lin Huang, Lixin Wen, Zengenni Liang, Zhihang Yuan, Jing Wu, Jine Yi

Publikováno v: Ecotoxicology and Environmental Safety, Vol 225, Iss , Pp 112746- (2021)

Betulinic acid (BA), a pentacyclic triterpenoid, has been associated with several biological effects, such as antioxidant, anti-inflammatory and antiviral activities. Previous studies have demonstrated that BA has the ability to alleviate intestinal

Externí odkaz: https://doaj.org/article/ef9f6e857bb948d2a0be0a45887ce8d1

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Akademický článek

γ-Oryzanol suppresses cell apoptosis by inhibiting reactive oxygen species-mediated mitochondrial signaling pathway in H2O2-stimulated L02 cells

Autor: Lin Huang, Weiwei Jiang, Lijuan Zhu, Chaoyang Ma, Zhaoping Ou, Chenxi Luo, Jing Wu, Lixin Wen, Zhuliang Tan, Jine Yi

Publikováno v: Biomedicine & Pharmacotherapy, Vol 121, Iss , Pp 109554- (2020)

γ-Oryzanol, a mixture of ferulic acid esters of plant sterols and triterpene alcohols existed in rice bran oil, can ameliorate lipid metabolism and enhance antioxidant activity. In this study, we used hydrogen peroxide (H2O2)-induced injury in human

Externí odkaz: https://doaj.org/article/470844907e2a433b91ef235cf5558adc

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Akademický článek

Gamma-oryzanol prevents ethanol-induced liver injury by ameliorating oxidative stress and modulating apoptosis-related protein expression in mice

Autor: Lijuan Zhu, Siting Xiang, Zhaoping Ou, Chaoyang Ma, Xianglian Yi, Lin Huang, Yurong Ma, Zengenni Liang, Zhihang Yuan, Lixin Wen, Rongfang Li, Jing Wu, Zhuliang Tan, Jine Yi

Publikováno v: Journal of Functional Foods, Vol 62, Iss , Pp - (2019)

Gamma-oryzanol (Orz), a mixture of ferulic acid esters of plant sterols and triterpene alcohols, has been proven to possess multiple activities. The purpose of this study was to explore the hepatoprotective effects and potential mechanisms of Orz aga

Externí odkaz: https://doaj.org/article/96da42643f484500bacddd0c37099ad9

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Akademický článek

Anti-inflammatory effect and potential mechanism of betulinic acid on λ-carrageenan-induced paw edema in mice

Autor: Zhaoping Ou, Jing Zhao, Lijuan Zhu, Lin Huang, Yurong Ma, Chaoyang Ma, Chenxi Luo, Zihan Zhu, Zhihang Yuan, Jing Wu, Rongfang Li, Jine Yi

Publikováno v: Biomedicine & Pharmacotherapy, Vol 118, Iss , Pp - (2019)

λ-Carrageenan (Carr), a seaweed polysaccharide, is used as a proinflammatory agent in research. Betulinic acid (BA), a naturally occurring pentacyclic triterpenoid, exerts immunomodulatory, antioxidant, anti-inflammatory, antitumor, anti-malarial an

Externí odkaz: https://doaj.org/article/53ef5ec5fecc40c8b813acf9017fe8af

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Betulinic acid attenuates cyclophosphamide-induced intestinal mucosa injury by inhibiting the NF-κB/MAPK signalling pathways and activating the Nrf2 signalling pathway

Autor: Lijuan Zhu, Zhaoping Ou, Lin Huang, Jing Wu, Xinyu Gao, Chenglong Huang, Li Kong, Xing Lin, Lixin Wen, Jine Yi, Zhihang Yuan, Zengenni Liang, Chaoyang Ma

Publikováno v: Ecotoxicology and Environmental Safety, Vol 225, Iss, Pp 112746-(2021)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::635f1b7d303c2761f5eb6cb39f664cfc
http://www.sciencedirect.com/science/article/pii/S0147651321008587

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Betulinic acid protects against renal damage by attenuation of oxidative stress and inflammation via Nrf2 signaling pathway in T-2 toxin-induced mice

Autor: Chaoyang Ma, Jing Wu, Lijuan Zhu, Zhihang Yuan, You Huang, Zhaoping Ou, Li Kong, Lin Huang, Haoqiang Zhao, Yazhi Chen, Jine Yi, Lixin Wen

Publikováno v: International immunopharmacology. 101

Betulinic acid (BA) is a pentacyclic triterpenoid compound with potential antioxidant and anti-inflammatory effects. In this study, T-2 toxin was injected intraperitoneally in mice to establish kidney damage model and to evaluate the protective effec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eac260b63a0fd073015b0188d4fa8bc
https://pubmed.ncbi.nlm.nih.gov/34628148

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Protective effects of betulinic acid on intestinal mucosal injury induced by cyclophosphamide in mice

Autor: Xianglian Yi, Zhuliang Tan, Jing Wu, Xihong Wang, Blazej Pozniak, Rongfang Li, Jine Yi, Bożena Obmińska-Mrukowicz, Zhaoping Ou, Lijuan Zhu, Zhihang Yuan

Publikováno v: Pharmacological Reports. 71:929-939

Background Betulinic acid (BA) is a plant-derived pentacyclic triterpenoid with a variety of biological activities. The purpose of this study was to assess the potential protective role of BA against intestinal mucosal injury induced by cyclophospham

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b9a84723188f5e36f8761ccca42e38
https://doi.org/10.1016/j.pharep.2019.05.004

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