Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Zhaoming Su"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Vesicular monoamine transporter 2 (VMAT2) belongs to the major facilitator superfamily (MFS), and mediates cytoplasmic monoamine packaging into presynaptic vesicles. Here, we present two cryo-EM structures of VMAT2, with a frog VMAT2 adoptin
Externí odkaz:
https://doaj.org/article/8a0ecf4eabd44d96a0ad9dc373c15b02
Autor:
Tian Hong, Qinghua Luo, Haiyun Ma, Xin Wang, Xinqiong Li, Chongrong Shen, Jie Pang, Yan Wang, Yuejia Chen, Changbin Zhang, Zhaoming Su, Haohao Dong, Xiaodi Tang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-10 (2024)
Abstract CRISPR‒Cas7-11 is a Type III-E CRISPR-associated nuclease that functions as a potent RNA editing tool. Tetratrico-peptide repeat fused with Cas/HEF1-associated signal transducer (TPR-CHAT) acts as a regulatory protein that interacts with C
Externí odkaz:
https://doaj.org/article/7a1960f67bde4591b7740fc6c6d71d32
Autor:
Lili Yang, Yujiao Chen, Shenghai Chang, Chongrong Shen, Xin Wang, Changbin Zhang, Zhibo Zhang, Bi-Sen Ding, Zhaoming Su, Haohao Dong, Xiaodi Tang
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/ca1549239e954489b63533e1395dc614
Autor:
Zhou Tong, Jianyu Tong, Wenwen Lei, Yufeng Xie, Yingzi Cui, Guowen Jia, Shihua Li, Zezhong Zhang, Zhimin Cheng, Xiao Xing, Haiyun Ma, Lan Deng, Rong Zhang, Xin Zhao, Kefang Liu, Qihui Wang, Jianxun Qi, Haomin Huang, Rui Song, Zhaoming Su, Guizhen Wu, Jing Lou, George Fu Gao
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114338- (2024)
Summary: The game between therapeutic monoclonal antibodies (mAbs) and continuously emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants has favored the virus, as most therapeutic mAbs have been evaded. Addressing this chall
Externí odkaz:
https://doaj.org/article/a73e673f4b47432cb7e3e0b7cbab3ca8
Autor:
Yan Wang, Chong Zhang, Yongbo Luo, Xiaobin Ling, Bingnan Luo, Guowen Jia, Dan Su, Haohao Dong, Zhaoming Su
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-9 (2023)
Abstract Respiratory syncytial virus (RSV) is a nonsegmented, negative strand RNA virus that has caused severe lower respiratory tract infections of high mortality rates in infants and the elderly, yet no effective vaccine or antiviral therapy is ava
Externí odkaz:
https://doaj.org/article/4e9714bad1894559ad41ee35a8a02f35
Autor:
Yan Wang, Xiaobin Ling, Chong Zhang, Jian Zou, Bingnan Luo, Yongbo Luo, Xinyu Jia, Guowen Jia, Minghua Zhang, Junchao Hu, Ting Liu, Yuanfeiyi Wang, Kefeng Lu, Dan Li, Jinbiao Ma, Cong Liu, Zhaoming Su
Publikováno v:
Molecular Biomedicine, Vol 4, Iss 1, Pp 1-14 (2023)
Abstract SARS-CoV-2 and its variants, with the Omicron subvariant XBB currently prevailing the global infections, continue to pose threats on public health worldwide. This non-segmented positive-stranded RNA virus encodes the multi-functional nucleoc
Externí odkaz:
https://doaj.org/article/0e7267bf39754639bc66cdc375359333
Autor:
Dongmei Tang, Tingting Jia, Yongbo Luo, Biqin Mou, Jie Cheng, Shiqian Qi, Shaohua Yao, Zhaoming Su, Yamei Yu, Qiang Chen
Publikováno v:
The Innovation, Vol 4, Iss 5, Pp 100495- (2023)
In the spacer acquisition stage of CRISPR-Cas immunity, spacer orientation and protospacer adjacent motif (PAM) removal are two prerequisites for functional spacer integration. Cas4 has been implicated in both processing the prespacer and determining
Externí odkaz:
https://doaj.org/article/da946df6c8184dc1b50fc1a82470b1b6
Autor:
Guangbing Zhang, Cuiyu Guo, Yan Wang, Xianda Zhang, Shuang Liu, Wen Qu, Chunxia Chen, Lingli Yan, Zhouning Yang, Zhixiong Zhang, Xiaohua Jiang, Xiaofeng Chen, Hong Liu, Qinhuai Lai, Xian Wei, Ying Lu, Shengyan Zhao, Han Deng, Yuxi Wang, Lin Yu, Hongbin Yu, Yu Wu, Zhaoming Su, Pengyu Chen, Ziqing Ren, Meng Yu, Feng Qu, Yong Luo, Lantu Gou, Qing Li, Ying Huang, Fanxin Ma, Jinliang Yang
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-6 (2022)
Abstract Anti-CD38 monoclonal antibodies (mAbs), daratumumab, and isatuximab have represented a breakthrough in the treatment of multiple myeloma (MM). Recently, CD38-based mAbs were expected to achieve increasing potential beyond MM, which encourage
Externí odkaz:
https://doaj.org/article/a39a57a1992548e1beadb485c54a357e
Autor:
Cai He, Jingyun Yang, Weiqi Hong, Zimin Chen, Dandan Peng, Hong Lei, Aqu Alu, Xuemei He, Zhenfei Bi, Xiaohua Jiang, Guowen Jia, Yun Yang, Yanan Zhou, Wenhai Yu, Cong Tang, Qing Huang, Mengli Yang, Bai Li, Jingmei Li, Junbin Wang, Haiying Que, Li Chen, Wenyan Ren, Dandan Wan, Jiong Li, Wei Wang, Guobo Shen, Zhiwei Zhao, Li Yang, Jinliang Yang, Zhenling Wang, Zhaoming Su, Yuquan Wei, Xiaobo Cen, Yoshimasa Tanaka, Xiangrong Song, Shuaiyao Lu, Xiaozhong Peng, Guangwen Lu, Xiawei Wei
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The SARS-CoV-2 Omicron variant has quickly become the predominant circulating variant, due to the high transmissibility and immune escape. Here, the authors develop a trimeric protein vaccine candidate and show a sustained humoral immune response, an
Externí odkaz:
https://doaj.org/article/6931d87e1b9f415882b4ac5ac20fee24
Autor:
Chang Liu, Hua Zhang, Xian Peng, Meghan S. Blackledge, Robert E. Furlani, Haoting Li, Zhaoming Su, Roberta J. Melander, Christian Melander, Suzanne Michalek, Hui Wu
Publikováno v:
mBio, Vol 14, Iss 3 (2023)
ABSTRACT Antibiotic tolerance within a biofilm community presents a serious public health challenge. Here, we report the identification of a 2-aminoimidazole derivative that inhibits biofilm formation by two pathogenic Gram-positive bacteria, Strepto
Externí odkaz:
https://doaj.org/article/343e3b9a42f041ec8cbd721edec050a8