Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Zhaomeng Sun"'
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186592 (2017)
Microglia-involved neuroinflammation is thought to promote brain damage in various neurodegenerative disorders. Thus, inhibition of microglial over-activation may have a therapeutic benefit for the treatment of neurodegenerative disorders. Michelioli
Externí odkaz:
https://doaj.org/article/d23583ec68d54d8f947c53ecde0b6c5b
Autor:
Yuanyuan Su, Zhaomeng Sun, Jun Chen, Yanxue Xue, Li Su, Yao Liang, Tanjun Tong, Lijun Zhao, Guodong Li, Qing Fang, Chenzhong Xu
Publikováno v:
Aging (Albany NY)
The activation of transcription factor NF-κB is currently identified as one of the driving forces to the aging process. Genetic impairment of NF-κB signaling pathway or pharmacological inhibition of NF-κB activity has been shown to extend healthsp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43602857a37f20b9b7be1c260e0c6165
http://europepmc.org/articles/PMC6535057
http://europepmc.org/articles/PMC6535057
Publikováno v:
Aging (Albany NY)
Senescent cells display the senescence-associated secretory phenotype (SASP) which plays important roles in cancer, aging, etc. Cell surface-bound IL-1α is a crucial SASP factor and acts as an upstream regulator to induce NF-κB activity and subsequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3692e29aea7b89b9aa06762d9853395d
http://europepmc.org/articles/PMC6366962
http://europepmc.org/articles/PMC6366962
Autor:
Shuqin Jia, Limin Han, Chenzhong Xu, Tanjun Tong, Jun Chen, Guodong Li, Na Zhang, Yao Liang, Nan Xie, Yuanyuan Su, Xiaofang Xing, Doudou Liu, Zhaomeng Sun
Publikováno v:
Cell Death & Differentiation. 29:1889-1889
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51b6b3eb064121b62c48ff20a17bcd0b
https://doi.org/10.1038/s41418-021-00806-y
https://doi.org/10.1038/s41418-021-00806-y
Autor:
Limin Han, Pan Wang, Hui Wang, Yuanyuan Su, Ganye Zhao, Pengfeng Wang, Zhaomeng Sun, Jun Chen, Zhao Wang, Tanjun Tong, Chenzhong Xu
Publikováno v:
Aging (Albany NY)
Sirtuin6 (SIRT6) has been implicated as a key factor in aging and aging-related diseases. However, the role of SIRT6 in cellular senescence has not been fully understood. Here, we show that SIRT6 repressed the expression of p27Kip1 (p27) in cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb3bfc86d4d9a9bc8b35f2c563784fc
https://doi.org/10.18632/aging.101038
https://doi.org/10.18632/aging.101038
Autor:
Hui Wang, Pengfeng Wang, Jun Chen, Chenzhong Xu, Guodong Li, Zhaomeng Sun, Yuanyuan Su, Limin Han, Tanjun Tong, Ganye Zhao, Hong Shen
Publikováno v:
Aging Cell
Summary Senescent cells display a senescence‐associated secretory phenotype (SASP) which contributes to tumor suppression, aging, and cancer. However, the underlying mechanisms for SASP regulation are not fully elucidated. SIRT1, a nicotinamide ade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::068358649bc1ad86bd8f9e9b0423dca0
https://doi.org/10.1111/acel.12511
https://doi.org/10.1111/acel.12511
Autor:
Jun Chen, Guodong Li, Zhaomeng Sun, Pengfeng Wang, Chenzhong Xu, Yuanyuan Su, Hong Shen, Tanjun Tong
Publikováno v:
Journal of Cell Science.
Senescent cells develop a senescence-associated secretory phenotype (SASP). The factors secreted by cells with a SASP have multiple biological functions that are mediated in an autocrine or paracrine manner. However, the status of the protein kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a06c11d2d68e67a235cf8b437b47a87
https://doi.org/10.1242/jcs.207217
https://doi.org/10.1242/jcs.207217
Autor:
Yuanyuan, Su, Pengfeng, Wang, Hong, Shen, Zhaomeng, Sun, Chenzhong, Xu, Guodong, Li, Tanjun, Tong, Jun, Chen
Publikováno v:
Journal of cell science. 131(6)
Senescent cells develop a senescence-associated secretory phenotype (SASP). The factors secreted by cells with a SASP have multiple biological functions that are mediated in an autocrine or paracrine manner. However, the status of the protein kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c035173a565f95297089867ea2ef7330
https://pubmed.ncbi.nlm.nih.gov/29420297
https://pubmed.ncbi.nlm.nih.gov/29420297
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 10, p e0186592 (2017)
PLoS ONE, Vol 12, Iss 10, p e0186592 (2017)
Microglia-involved neuroinflammation is thought to promote brain damage in various neurodegenerative disorders. Thus, inhibition of microglial over-activation may have a therapeutic benefit for the treatment of neurodegenerative disorders. Michelioli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::098755d8355a65ce911bbffb6558e404
https://pubmed.ncbi.nlm.nih.gov/29040306
https://pubmed.ncbi.nlm.nih.gov/29040306
Autor:
Yuanyuan Su, Pengfeng Wang, Hong Shen, Zhaomeng Sun, Chenzhong Xu, Guodong Li, Tanjun Tong, Jun Chen
Publikováno v:
Journal of Cell Science; 3/15/2018, Vol. 131 Issue 6, p1-14, 14p