Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Zhaokui Cai"'
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103149- (2024)
Summary: Virus-to-host RNA-RNA interactions directly regulate host mRNA stability and viral replication. However, globally profiling virus-to-host in situ RNA-RNA interactions remains challenging. Here, we present an RNA in situ conformation sequenci
Externí odkaz:
https://doaj.org/article/c0ec8f90f8674b27ac5c7ba6db4ff132
Autor:
Changchang Cao, Zhaokui Cai, Xia Xiao, Jian Rao, Juan Chen, Naijing Hu, Minnan Yang, Xiaorui Xing, Yongle Wang, Manman Li, Bing Zhou, Xiangxi Wang, Jianwei Wang, Yuanchao Xue
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Secondary structures and long-range RNA interactions of the SARS-CoV-2 genome have been investigated by various sequencing methods. Here the authors use an RNA-RNA hybrid sequencing method to predict the secondary and tertiary structure of the SRAS-C
Externí odkaz:
https://doaj.org/article/9e50f430b49c49a7bdba77035d1bc6ef
Autor:
Hailian Zhao, Zhaokui Cai, Jiang Rao, Di Wu, Rong Ye, Di Wang, Juan Chen, Lei Ji, Changchang Cao, Naijing Hu, Ting Shu, Ping Zhu, Jianwei Wang, Xi Zhou, Yuanchao Xue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6488167f3e02f4b453295550f4f91671
https://doi.org/10.2139/ssrn.4369784
https://doi.org/10.2139/ssrn.4369784
Autor:
Lei Ji, Juan Chen, Zongchang Du, Lei Wang, Rong Ye, Cong Xia, Zhaokui Cai, Sui Wang, Shunmin He, Xiaohua Yu, Naijing Hu, Yuanchao Xue, Di Wang, Changchang Cao, Xianguang Yang
Publikováno v:
Nature. 582:432-437
Highly structured RNA molecules usually interact with each other, and associate with various RNA-binding proteins, to regulate critical biological processes. However, RNA structures and interactions in intact cells remain largely unknown. Here, by co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5660a332274b5b0c17e9711b0b48d5e
https://doi.org/10.1038/s41586-020-2249-1
https://doi.org/10.1038/s41586-020-2249-1
Publikováno v:
WIREs RNA. 13
Pervasive transcription of the human genome generates a massive amount of noncoding RNAs (ncRNAs) that lack protein-coding potential but play crucial roles in development, differentiation, and tumorigenesis. To achieve these biological functions, ncR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea61ce05bb98b9aa07fe26f327011ea
https://doi.org/10.1002/wrna.1712
https://doi.org/10.1002/wrna.1712
Autor:
Bing Zhou, Yuanchao Xue, Changchang Cao, Xiaorui Xing, Xiangxi Wang, Yongle Wang, Zhaokui Cai, Naijing Hu, Jianwei Wang, Jian Rao, Xia Xiao, Manman Li, Minnan Yang, Juan Chen
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
SARS-CoV-2 carries the largest single-stranded RNA genome and is the causal pathogen of the ongoing COVID-19 pandemic. How the SARS-CoV-2 RNA genome is folded in the virion remains unknown. To fill the knowledge gap and facilitate structure-based dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61c68292432e85155b3df9b311955dd2
http://europepmc.org/articles/PMC8225788
http://europepmc.org/articles/PMC8225788
Autor:
Jian Rao, Xiangxi Wang, Yuanchao Xue, Bing Zhou, Changchang Cao, Xiaorui Xing, Zhaokui Cai, Naijing Hu, Jianwei Wang, Xia Xiao, Minnan Yang
SARS-CoV-2 carries the largest single-stranded RNA genome and is the causal pathogen of the ongoing COVID-19 pandemic. How the SARS-CoV-2 RNA genome is folded in the virion remains unknown. To fill the knowledge gap and facilitate structure-based dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76e0ff655ab865ca02fab1989ab832c7
https://doi.org/10.21203/rs.3.rs-132578/v1
https://doi.org/10.21203/rs.3.rs-132578/v1
Publikováno v:
Nature protocols. 16(6)
Emerging evidence has demonstrated that RNA-RNA interactions are vital in controlling diverse biological processes, including transcription, RNA splicing and protein translation. RNA in situ conformation sequencing (RIC-seq) is a technique for captur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe24733eaf8e247f5a9d3a644f601a3
https://pubmed.ncbi.nlm.nih.gov/34021296
https://pubmed.ncbi.nlm.nih.gov/34021296
Autor:
Hailian Zhao, Wen-Long Lei, Ruibao Su, Zhaokui Cai, Catherine C L Wong, Ligang Wu, Yong Tian, Lei Wang, Li-Hua Fan, Zongchang Du, Shunmin He, Xiaoxiao Zhu, Qian Zhou, Yue Wang, Yuanchao Xue, Changchang Cao, Qing-Yuan Sun, Ying-Chun Ouyang, Nan Zhang
Publikováno v:
Nature cell biology. 23(6)
RNA-binding proteins (RBPs) have essential functions during germline and early embryo development. However, current methods are unable to identify the in vivo targets of a RBP in these low-abundance cells. Here, by coupling RBP-mediated reverse trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85eb1ee329d3acd208218b21ed89691d
https://pubmed.ncbi.nlm.nih.gov/34108658
https://pubmed.ncbi.nlm.nih.gov/34108658
Autor:
Dongwan Cheng, Wen Zhong, Tao Xu, Junjie Hou, Qiang Hao, Maoge Zhou, Zhaokui Cai, Hongyang Liu, Zonghong Li, Xihao Hu, Yifa Zhou, Yuanchao Xue, Pingyong Xu
Publikováno v:
Nucleic Acids Research
The molecular mechanism in pancreatic β cells underlying hyperlipidemia and insulin insufficiency remains unclear. Here, we find that the fatty acid-induced decrease in insulin levels occurs due to a decrease in insulin translation. Since regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::821a40ba9063b6496ff39573a8e71be0
https://doi.org/10.1093/nar/gky867
https://doi.org/10.1093/nar/gky867