Výsledky vyhledávání - "Zhaojin Zeng"

Akademický článek

α1-adrenoceptor stimulation ameliorates lipopolysaccharide-induced lung injury by inhibiting alveolar macrophage inflammatory responses through NF-κB and ERK1/2 pathway in ARDS

Autor: Zhukai Cong, Cui Yang, Zhaojin Zeng, Changyi Wu, Feng Zhao, Ziyuan Shen, Han Xiao, Xi Zhu

Publikováno v: Frontiers in Immunology, Vol 13 (2023)

IntroductionCatecholamines such as norepinephrine or epinephrine have been reported to participate in the development of acute respiratory distress syndrome (ARDS) by activating adrenergic receptors (ARs). But the role of α1-AR in this process has y

Externí odkaz: https://doaj.org/article/b71f2be8858e4d74893032090f4441ea

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Akademický článek

Tetrandrine Modulates Rheb-mTOR Signaling-Mediated Selective Autophagy and Protects Pulmonary Fibrosis

Autor: Yuanyuan Liu, Wenshan Zhong, Jinming Zhang, Weimou Chen, Ye lu, Yujie Qiao, Zhaojin Zeng, Haohua Huang, Shaoxi Cai, Hangming Dong

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

Idiopathic pulmonary fibrosis is a progressive fatal disease characterized by interstitial remodeling, with high lethality and a lack of effective medical therapies. Tetrandrine has been proposed to present anti-fibrotic effects, but the efficacy and

Externí odkaz: https://doaj.org/article/bca73e8f2be449509de5b840f1899701

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Akademický článek

Anlotinib Inhibits PFKFB3-Driven Glycolysis in Myofibroblasts to Reverse Pulmonary Fibrosis

Autor: Weimou Chen, Jinming Zhang, Wenshan Zhong, Yuanyuan Liu, Ye Lu, Zhaojin Zeng, Haohua Huang, Xuan Wan, Xiaojing Meng, Fei Zou, Shaoxi Cai, Hangming Dong

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

Idiopathic pulmonary fibrosis (IPF) is a fatal disease in which the normal alveolar network is gradually replaced by fibrotic scars. Current evidence suggests that metabolic alterations correlate with myofibroblast activation in IPF. Anlotinib has be

Externí odkaz: https://doaj.org/article/4b2c709e8af04cf4ab67462c74d81538

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Akademický článek

Extracellular HSP90α Interacts With ER Stress to Promote Fibroblasts Activation Through PI3K/AKT Pathway in Pulmonary Fibrosis

Autor: Jinming Zhang, Wenshan Zhong, Yuanyuan Liu, Weimou Chen, Ye Lu, Zhaojin Zeng, Yujie Qiao, Haohua Huang, Xuan Wan, Wei Li, Xiaojing Meng, Fei Zou, Shaoxi Cai, Hangming Dong

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

Pulmonary fibrosis is characterized by alveolar epithelial cell injury, lung fibroblast proliferation, differentiation, and extracellular matrix (ECM) deposition. Our previous study indicated that extracellular HSP90α (eHSP90α) promotes pulmonary f

Externí odkaz: https://doaj.org/article/2930a891803a4d0e9dcee867bdb9333c

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