Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Zhaohao Huang"'
Autor:
Jianjie Lv, Chun Zhang, Xiuxing Liu, Chenyang Gu, Yidan Liu, Yuehan Gao, Zhaohao Huang, Qi Jiang, Binyao Chen, Daquan He, Tianfu Wang, Zhuping Xu, Wenru Su
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Background Aging is a holistic change that has a major impact on the immune system, and immunosenescence contributes to the overall progression of aging. The bone marrow is the most important hematopoietic immune organ, while the spleen, as
Externí odkaz:
https://doaj.org/article/ff9c571ed510433c89e666f5aaf0d37e
Autor:
Xiuxing Liu, Chenyang Gu, Jianjie Lv, Qi Jiang, Wen Ding, Zhaohao Huang, Yidan Liu, Yuhan Su, Chun Zhang, Zhuping Xu, Xianggui Wang, Wenru Su
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-19 (2023)
Abstract Background Autoimmune uveitis (AU) is the most common ophthalmic autoimmune disease (AD) and is characterized by a complex etiology, high morbidity, and high rate of blindness. AU remission has been observed in pregnant female patients. Howe
Externí odkaz:
https://doaj.org/article/237d27220310489b8bb253ac27fe88be
Autor:
He Li, Lihui Xie, Lei Zhu, Zhaohuai Li, Rong Wang, Xiuxing Liu, Zhaohao Huang, Binyao Chen, Yuehan Gao, Lai Wei, Chang He, Rong Ju, Yizhi Liu, Xialin Liu, Yingfeng Zheng, Wenru Su
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Uveitis is a complex autoimmune inflammatory disease of the eye and defining molecules involved is a priority. Here the authors use scRNA sequencing in mouse experimental autoimmune uveitis (EAU) and show PIM1 promotes the imbalance of Th17 and Treg
Externí odkaz:
https://doaj.org/article/3de0bb06a46c4495a6905c2ddbef0237
Autor:
Xiuxing Liu, Yuhan Su, Zhaohao Huang, Jianjie Lv, Chenyang Gu, Zhuang Li, Tianyu Tao, Yidan Liu, Qi Jiang, Runping Duan, Binyao Chen, Rong Ju, Xianggui Wang, Yingfeng Zheng, Wenru Su
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 5, Pp n/a-n/a (2023)
Abstract Background Sleep loss (SL) is a health issue associated with the higher risk of autoimmune and inflammatory disorders. However, the connection between SL, the immune system, and autoimmune diseases remains unknown. Methods We conducted mass
Externí odkaz:
https://doaj.org/article/acd9445e7a1d453493e3bf067c69c366
Autor:
Xiuxing Liu, Qi Jiang, Jianjie Lv, Shizhao Yang, Zhaohao Huang, Runping Duan, Tianyu Tao, Zhaohuai Li, Rong Ju, Yingfeng Zheng, Wenru Su
Publikováno v:
JCI Insight, Vol 7, Iss 23 (2022)
Vogt-Koyanagi-Harada disease (VKH) is an important refractory uveitis mediated by pathological T cells (TCs). Tofacitinib (TOFA) is a JAK- targeted therapy for several autoimmune diseases. However, the specific pathogenesis and targeted therapeutics
Externí odkaz:
https://doaj.org/article/6cd4c1a654e34e1083edf2a3e91eac6b
Autor:
Xiuxing Liu, Binyao Chen, Zhaohao Huang, Runping Duan, He Li, Lihui Xie, Rong Wang, Zhaohuai Li, Yuehan Gao, Yingfeng Zheng, Wenru Su
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Liu et al. use mass cytometry and single-cell RNA sequencing of healthy human blood samples to obtain a comprehensive human immune cell landscape when sleep duration is reduced. Their findings could provide highdimensional insight into the cellular a
Externí odkaz:
https://doaj.org/article/e8dc70b7415c4a6babbdda9affd52feb
Autor:
Shizhao Yang, Tianyu Tao, Zhaohao Huang, Xiuxing Liu, He Li, Lihui Xie, Feng Wen, Wei Chi, Wenru Su
Publikováno v:
Frontiers in Medicine, Vol 8 (2022)
Background: No study explores the effectiveness of adalimumab in sight-threatening Vogt-Koyanagi-Harada (VKH) patients in China.Objective: To evaluate the short-term effectiveness and safety of adalimumab (ADA) in patients with sight-threatening Vogt
Externí odkaz:
https://doaj.org/article/e6f321b8b79e43498aa8bcf3bb14836b
Autor:
Yingfeng Zheng, Xiuxing Liu, Wenqing Le, Lihui Xie, He Li, Wen Wen, Si Wang, Shuai Ma, Zhaohao Huang, Jinguo Ye, Wen Shi, Yanxia Ye, Zunpeng Liu, Moshi Song, Weiqi Zhang, Jing-Dong J. Han, Juan Carlos Izpisua Belmonte, Chuanle Xiao, Jing Qu, Hongyang Wang, Guang-Hui Liu, Wenru Su
Publikováno v:
Protein & Cell, Vol 11, Iss 10, Pp 740-770 (2020)
Abstract Age-associated changes in immune cells have been linked to an increased risk for infection. However, a global and detailed characterization of the changes that human circulating immune cells undergo with age is lacking. Here, we combined scR
Externí odkaz:
https://doaj.org/article/23cd9fa05c7a4f1f9348ea29fcaf59ef
Publikováno v:
Allergology International, Vol 69, Iss 1, Pp 35-45 (2020)
Allergic diseases, which include asthma, allergic skin diseases, allergic rhinitis and allergic conjunctivitis, have already garnered worldwide public health attention over recent decades. Mesenchymal stem cells (MSCs) have gradually emerged as a pot
Externí odkaz:
https://doaj.org/article/585592f45228461ebcf9e70fdbf0a26d
Autor:
Shizhao Yang, Zhaohao Huang, Yunwei Hu, Jian Zhang, Xiuxing Liu, He Li, Lihui Xie, Feng Wen, Dan Liang, Wenru Su
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: No study has evaluated the effectiveness of Adalimumab (ADA) as first-line in treatment-naïve patients with retinal vasculitis due to Behçet’s Uveitis (BU).Objective: To compare the efficacy of ADA plus conventional therapy and conven
Externí odkaz:
https://doaj.org/article/3df7d98362764b94a79fae7de7f0f119