Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Zhaofeng Gao"'
Publikováno v:
Meitan xuebao, Vol 49, Iss 4, Pp 1976-1988 (2024)
Aiming at the difficulty in detecting concealed geological isomers using conventional geophysical method in ultra-wide coal working face, the electromagnetic response mechanism of mine transient electromagnetic (TEM) perspective detection with opposi
Externí odkaz:
https://doaj.org/article/6df8267e533842e69647d92128f1ff19
Autor:
Huihui Gao, Zhaofeng Gao, Xiaobei Liu, Xu Sun, Zhonghui Hu, Zhengwei Song, Cheng Zhang, Jianguo Fei, Xiaoguang Wang
Publikováno v:
Cell Division, Vol 19, Iss 1, Pp 1-15 (2024)
Abstract Background The molecular targets and associated mechanisms of hepatocellular carcinoma (HCC) have been widely studied, but the roles of PDZK1 in HCC are unclear. Therefore, the aim of this study is to explore the role and associated mechanis
Externí odkaz:
https://doaj.org/article/7d8a2be00e0e48549733fcaf1a9f48c1
Autor:
Fei Chen, Jian Sheng, Xiaoping Li, Zhaofeng Gao, Siqi Zhao, Lingyu Hu, Minjie Chen, Jianguo Fei, Zhengwei Song
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116659- (2024)
Cholangiocarcinoma (CCA), a rare yet notably aggressive cancer, has experienced a surge in incidence in recent years. Presently, surgical resection remains the most effective curative strategy for CCA. Nevertheless, a majority of patients with CCA ar
Externí odkaz:
https://doaj.org/article/6ed52cfd8cb244ce9f34dc0d3ae77a6d
Autor:
Minjie Chen, Fei Chen, Zhaofeng Gao, Xiaoping Li, Lingyu Hu, Shuying Yang, Siqi Zhao, Zhengwei Song
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 117045- (2024)
The interaction between the immune system and the tumor matrix has a huge impact on the progression and treatment of cancer. This paper summarizes and discusses the crosstalk between T cells and cancer-associated fibroblasts (CAFs). CAFs can also pro
Externí odkaz:
https://doaj.org/article/79a2617019614addb931f850bc046d5e
Autor:
Bartosz Mucha, Shuo Qie, Sagar Bajpai, Vincenzo Tarallo, J. Nathaniel Diehl, Frank Tedeschi, Gao Zhou, Zhaofeng Gao, Samuel Flashner, Andres J. Klein-Szanto, Hanina Hibshoosh, Shimonosono Masataka, Olga S. Chajewski, Ireneusz Majsterek, Dariusz Pytel, Maria Hatzoglou, Channing J. Der, Hiroshi Nakagawa, Adam J. Bass, Kwok-Kin Wong, Serge Y. Fuchs, Anil K. Rustgi, Eckhard Jankowsky, J. Alan Diehl
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Cytoplasmic accumulation of RNA binding protein, hnRNPK in cancer cells is associated with poor prognosis. Here the authors show that SCFFbxo4 E3 ubiquitin ligase-mediated polyubiquitylation of hnRNPK restricts c-Myc translation and limits cancer pro
Externí odkaz:
https://doaj.org/article/fecd2f81e26b43a3b3aad7932728969f
Autor:
Chien-Wen Chen, Bo-Jhih Guan, Mohammed R. Alzahrani, Zhaofeng Gao, Long Gao, Syrena Bracey, Jing Wu, Cheikh A. Mbow, Raul Jobava, Leena Haataja, Ajay H. Zalavadia, Ashleigh E. Schaffer, Hugo Lee, Thomas LaFramboise, Ilya Bederman, Peter Arvan, Clayton E. Mathews, Ivan C. Gerling, Klaus H. Kaestner, Boaz Tirosh, Feyza Engin, Maria Hatzoglou
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Pancreatic β-cells are naturally prone to ER stress due to their role in insulin production and secretion. Here, the authors show that chronic ER stress adaptive exhaustion results in an irreversible loss of β-cell function leading to T1D pathogene
Externí odkaz:
https://doaj.org/article/adc88863189241eabee325b0cf1b9532
Autor:
David Danielpour, Zhaofeng Gao, Patrick M. Zmina, Eswar Shankar, Benjamin C. Shultes, Raul Jobava, Scott M. Welford, Maria Hatzoglou
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Abstract The imidazolium compound YM155, first discovered as a potent inhibitor of Survivin, effectively kills many carcinomas in preclinical models. However, the upstream signaling mechanism triggered by YM155 remains unclear. Here we studied early
Externí odkaz:
https://doaj.org/article/413a98d689b543009470d4c60ab64d4b
Autor:
Kenneth T Farabaugh, Dawid Krokowski, Bo-Jhih Guan, Zhaofeng Gao, Xing-Huang Gao, Jing Wu, Raul Jobava, Greeshma Ray, Tristan J de Jesus, Massimiliano G Bianchi, Evelyn Chukwurah, Ovidio Bussolati, Michael Kilberg, David A Buchner, Ganes C Sen, Calvin Cotton, Christine McDonald, Michelle Longworth, Parameswaran Ramakrishnan, Maria Hatzoglou
Publikováno v:
eLife, Vol 9 (2020)
The inability of cells to adapt to increased environmental tonicity can lead to inflammatory gene expression and pathogenesis. The Rel family of transcription factors TonEBP and NF-κB p65 play critical roles in the switch from osmoadaptive homeostas
Externí odkaz:
https://doaj.org/article/bfbaa90f7d4c41fb9bf0e7ea7e264f23
Autor:
Zhaofeng Gao, Miles Wilkinson
Publikováno v:
F1000Research, Vol 6 (2017)
Nonsense-mediated RNA decay (NMD) is a highly conserved and selective RNA turnover pathway that has been subject to intense scrutiny. NMD identifies and degrades subsets of normal RNAs, as well as abnormal mRNAs containing premature termination codon
Externí odkaz:
https://doaj.org/article/1e827e9b0ab94f4282992fae49b1187b
Autor:
Zhaofeng Gao, Andrea A Putnam, Heath A Bowers, Ulf-Peter Guenther, Xuan Ye, Audrey Kindsfather, Angela K Hilliker, Eckhard Jankowsky
Publikováno v:
eLife, Vol 5 (2016)
Eukaryotic translation initiation involves two conserved DEAD-box RNA helicases, eIF4A and Ded1p. Here we show that S. cerevisiae eIF4A and Ded1p directly interact with each other and simultaneously with the scaffolding protein eIF4G. We delineate a
Externí odkaz:
https://doaj.org/article/32b74e867b61434bbce9602bd54e81fd