Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Zhaofa Xu"'
Publikováno v:
PLoS Genetics, Vol 19, Iss 4, p e1010740 (2023)
Oxidative stress response is a fundamental biological process mediated by conserved mechanisms. The identities and functions of some key regulators remain unknown. Here, we report a novel role of C. elegans casein kinase 1 gamma CSNK-1 (also known as
Externí odkaz:
https://doaj.org/article/842d03bda54b4932b1effb19aca4618f
Autor:
Xianchao Du, Jiashuo Li, Minghui Li, Xinxin Yang, Zhipeng Qi, Bin Xu, Wei Liu, Zhaofa Xu, Yu Deng
Publikováno v:
Cell & Bioscience, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Glutamate (Glu) is the predominant excitatory neurotransmitter in the central nervous system (CNS). Glutamatergic transmission is critical for controlling neuronal activity. In presynaptic neurons, Glu is stored in synaptic vesicles and rele
Externí odkaz:
https://doaj.org/article/d8bd142ab9a5444b836f5b4a36ba8048
Autor:
Xuda Liu, Haiying Wang, Bingchen Liu, Zhipeng Qi, Jiashuo Li, Bin Xu, Wei Liu, Zhaofa Xu, Yu Deng
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Eukaryotic messenger mRNAs contain many RNA methyl chemical modifications, in which N6-methyladenosine (m6A) plays a very important role. The modification process of RNA methylation is a dynamic reversible regulatory process that is mainly catalyzed
Externí odkaz:
https://doaj.org/article/3ad79684192b4cb7b9205061c65bd6a6
Autor:
Jiashuo Li, Xinxin Yang, Zhipeng Qi, Yanqi Sang, Yanan Liu, Bin Xu, Wei Liu, Zhaofa Xu, Yu Deng
Publikováno v:
Cell & Bioscience, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract Epitranscriptomics, also known as “RNA epigenetics”, is a chemical modification for RNA regulation. Ribonucleic acid (RNA) methylation is considered to be a major discovery following the deoxyribonucleic acid (DNA) and histone methylatio
Externí odkaz:
https://doaj.org/article/83bb28a8b54d4d0d9b733a4eb4946b1e
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
In December 2019, the 2019 novel coronavirus disease (COVID-19), which has been identified to be caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in China and spread across the world. Higher plasma levels of cytokines,
Externí odkaz:
https://doaj.org/article/f4074f125d194ef5ab5808d33904f2d0
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-2 (2021)
Externí odkaz:
https://doaj.org/article/8ba1612a65364753a510c055e02c643f
Autor:
Zhaofa Xu, Yiman Hu, Yajun Deng, Yutao Chen, Hanqi Hua, Siyu Huang, Qian Nie, Qian Pan, Dengke K. Ma, Long Ma
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 11, Pp 3515-3527 (2018)
Animals utilize conserved mechanisms to regulate oxidative stress. The C. elegans SKN-1 protein is homologous to the vertebrate Nrf (NF-E2-related factor) family of cap ’n’ collar (CnC) transcription factors and functions as a core regulator of x
Externí odkaz:
https://doaj.org/article/d7c38382648942e1a64519b83358ebda
Autor:
Zhiping Tan, Hui Zeng, Zhaofa Xu, Qi Tian, Xiaoyang Gao, Chuanman Zhou, Yu Zheng, Jian Wang, Guanghui Ling, Bing Wang, Yifeng Yang, Long Ma
Publikováno v:
BMC Medical Genetics, Vol 19, Iss 1, Pp 1-9 (2018)
Abstract Background Ankylosing spondylitis (AS) is a debilitating autoimmune disease affecting tens of millions of people in the world. The genetics of AS is unclear. Analysis of rare AS pedigrees might facilitate our understanding of AS pathogenesis
Externí odkaz:
https://doaj.org/article/d554e726c88d4e1d99501c947fc5101f
Nucleoli and the nucleoli–centromere association are dynamic during normal development and in cancer
Autor:
Aaron Rodrigues, Kyle L. MacQuarrie, Emma Freeman, Alicia Lin, Alexander B. Willis, Zhaofa Xu, Angel A. Alvarez, Yongchao Ma, Bethany E. Perez White, Daniel R. Foltz, Sui Huang
Publikováno v:
Molecular Biology of the Cell. 34
In this study, the authors show nucleoli and centromeres interact dynamically not only during normal differentiation across a variety of cellular models including myocytes, keratinocytes, and neurons, but in cancer cells as well. Differentiation lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bb91197f9ef571c735e261ebe7bf169
https://doi.org/10.1091/mbc.e22-06-0237
https://doi.org/10.1091/mbc.e22-06-0237
Autor:
Miller, Nimrod, Zhaofa Xu, Quinlan, Katharina A., Amy Ji, McGivern, Jered V., Zhihua Feng, Han Shi, Chien-Ping Ko, Li-Hue, Heckman, Charles J., Ebert, Allison D., Ma, Yongchao C.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 11/21/2023, Vol. 120 Issue 47, p1-12, 16p