Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Zhaofa Wu"'
Autor:
Péter Berki, Csaba Cserép, Zsuzsanna Környei, Balázs Pósfai, Eszter Szabadits, Andor Domonkos, Anna Kellermayer, Miklós Nyerges, Xiaofei Wei, Istvan Mody, Araki Kunihiko, Heinz Beck, He Kaikai, Wang Ya, Nikolett Lénárt, Zhaofa Wu, Miao Jing, Yulong Li, Attila I. Gulyás, Ádám Dénes
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Acute brain slices represent a workhorse model for studying the central nervous system (CNS) from nanoscale events to complex circuits. While slice preparation inherently involves tissue damage, it is unclear how microglia, the main immune c
Externí odkaz:
https://doaj.org/article/23b86858b05540109a8a453d5e619efd
Autor:
Koustav Roy, Xuzhao Zhou, Rintaro Otani, Ping-Chuan Yuan, Shuji Ioka, Kaspar E. Vogt, Tamae Kondo, Nouran H. T. Farag, Haruto Ijiri, Zhaofa Wu, Youhei Chitose, Mao Amezawa, David S. Uygun, Yoan Cherasse, Hiroshi Nagase, Yulong Li, Masashi Yanagisawa, Manabu Abe, Radhika Basheer, Yi-Qun Wang, Tsuyoshi Saitoh, Michael Lazarus
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Optochemistry, an emerging pharmacologic approach in which light is used to selectively activate or deactivate molecules, has the potential to alleviate symptoms, cure diseases, and improve quality of life while preventing uncontrolled drug
Externí odkaz:
https://doaj.org/article/4431e78e019340f7971afef4a23b66d7
Autor:
Ildar T. Bayazitov, Brett J.W. Teubner, Feng Feng, Zhaofa Wu, Yulong Li, Jay A. Blundon, Stanislav S. Zakharenko
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113758- (2024)
Summary: Meaningful auditory memories are formed in adults when acoustic information is delivered to the auditory cortex during heightened states of attention, vigilance, or alertness, as mediated by neuromodulatory circuits. Here, we identify that,
Externí odkaz:
https://doaj.org/article/f1b401eb1b054cd1855edbe28624e815
Autor:
Zhaofa Wu, Chengfeng Liu
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0307878 (2024)
To simulate the nonlinear stress-strain curve of rocks under static loads and contribute to the design and construction of rock engineering structures, a constitutive model has been proposed based on the elastic modulus E decreasing with the increase
Externí odkaz:
https://doaj.org/article/cf3464180ae0477eadb3d3eba77d5cdb
Autor:
Wanling Peng, Xiaotong Liu, Guofen Ma, Zhaofa Wu, Ziyue Wang, Xiang Fei, Meiling Qin, Lizhao Wang, Yulong Li, Siyu Zhang, Min Xu
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-25 (2023)
Abstract Astrocytes play a crucial role in regulating sleep–wake behavior, and adenosine signaling is generally thought to be involved. Here we show multiple lines of evidence supporting that modulation of the sleep–wake behavior by astrocyte Ca2
Externí odkaz:
https://doaj.org/article/9c675df3ac1a4b12b29bd9596c539343
Publikováno v:
eLife, Vol 10 (2021)
Vesicular neurotransmitter transporters (VNTs) mediate the selective uptake and enrichment of small-molecule neurotransmitters into synaptic vesicles (SVs) and are therefore a major determinant of the synaptic output of specific neurons. To identify
Externí odkaz:
https://doaj.org/article/4102e0d2badc4b2089608a6b3379cab9
Autor:
Huasheng Yu, Tianjun Zhao, Simin Liu, Qinxue Wu, Omar Johnson, Zhaofa Wu, Zihao Zhuang, Yaocheng Shi, Luxin Peng, Renxi He, Yong Yang, Jianjun Sun, Xiaoqun Wang, Haifeng Xu, Zheng Zeng, Peng Zou, Xiaoguang Lei, Wenqin Luo, Yulong Li
Publikováno v:
eLife, Vol 8 (2019)
Patients with liver diseases often suffer from chronic itch, yet the pruritogen(s) and receptor(s) remain largely elusive. Here, we identify bile acids as natural ligands for MRGPRX4. MRGPRX4 is expressed in human dorsal root ganglion (hDRG) neurons
Externí odkaz:
https://doaj.org/article/4548ec382217470083b1f9c69579733d
Autor:
Koustav Roy, Xuzhao Zhou, Rintaro Otani, Ping-Chuan Yuan, Shuji Ioka, Vogt, Kaspar E., Tamae Kondo, Farag, Nouran H. T., Haruto Ijiri, Zhaofa Wu, Youhei Chitose, Mao Amezawa, Uygun, David S., Yoan Cherasse, Hiroshi Nagase, Yulong Li, Masashi Yanagisawa, Manabu Abe, Basheer, Radhika, Yi-Qun Wang
Publikováno v:
Nature Communications; 4/30/2024, Vol. 15 Issue 1, p1-17, 17p, 6 Graphs
Autor:
Xinyang Li, Yixin Li, Yiliang Zhou, Jiamin Wu, Zhifeng Zhao, Jiaqi Fan, Fei Deng, Zhaofa Wu, Guihua Xiao, Jing He, Yuanlong Zhang, Guoxun Zhang, Xiaowan Hu, Xingye Chen, Yi Zhang, Hui Qiao, Hao Xie, Yulong Li, Haoqian Wang, Lu Fang, Qionghai Dai
Publikováno v:
Nature Biotechnology. 41:282-292
A fundamental challenge in fluorescence microscopy is the photon shot noise arising from the inevitable stochasticity of photon detection. Noise increases measurement uncertainty and limits imaging resolution, speed and sensitivity. To achieve high-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dae4c10f9139406e0a835b260ab9e35
https://doi.org/10.1038/s41587-022-01450-8
https://doi.org/10.1038/s41587-022-01450-8
Autor:
Zhaofa Wu, Yuting Cui, Huan Wang, Hao Wu, Yi Wan, Bohan Li, Lei Wang, Sunlei Pan, Wanling Peng, Ao Dong, Zhengwei Yuan, Miao Jing, Min Xu, Minmin Luo, Yulong Li
Publikováno v:
Proceedings of the National Academy of Sciences. 120
The purinergic signaling molecule adenosine (Ado) modulates many physiological and pathological functions in the brain. However, the exact source of extracellular Ado remains controversial. Here, utilizing a newly optimized genetically encoded GPCR-A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cf52f004f655b6eebe9aba7916b31e3
https://doi.org/10.1073/pnas.2212387120
https://doi.org/10.1073/pnas.2212387120