Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Zhaoda Zhang"'
Publikováno v:
iRADIOLOGY, Vol 1, Iss 2, Pp 120-127 (2023)
Abstract Background Fluorine‐18 labeled N‐(4‐chloro‐3‐(((fluoro‐18F)methyl‐d2)thio)phenyl)picolinamide, [18F]mG4P027, is a potent positron emission tomography (PET) radiotracer for mGluR4. Our previous in vitro and in vivo evaluations h
Externí odkaz:
https://doaj.org/article/e415ec877aca4d76b5328db4bc808788
Autor:
Taylor Marie Richards, Aixia Sun, Hasaan Hayat, Neil Robertson, Zhaoda Zhang, Jinda Fan, Ping Wang
Publikováno v:
Life, Vol 10, Iss 9, p 213 (2020)
Islet transplantation has great potential as a cure for type 1 diabetes. At present; the lack of a clinically validated non-invasive imaging method to track islet grafts limits the success of this treatment. Some major clinical imaging modalities and
Externí odkaz:
https://doaj.org/article/881f32d8bb824cb1b576ef892c029d61
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71309 (2013)
The platelet-derived growth factor (PDGF) signaling pathway has been found to play important roles in the development and progression of human cancers by regulating the processes of cell proliferation, apoptosis, migration, invasion, metastasis, and
Externí odkaz:
https://doaj.org/article/e9f15c952f684a9fa6020cce891d0ce6
Autor:
Junfeng Wang, Sung‐Hyun Moon, Michael B. Cleary, Timothy M. Shoup, Georges El Fakhri, Zhaoda Zhang, Anna‐Liisa Brownell
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 66:34-40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::462a46f12d8021bf9fa27069da5e60cd
https://doi.org/10.1002/jlcr.4011
https://doi.org/10.1002/jlcr.4011
Autor:
Junfeng, Wang, Sung-Hyun, Moon, Michael B, Cleary, Timothy M, Shoup, Georges, El Fakhri, Zhaoda, Zhang, Anna-Liisa, Brownell
Publikováno v:
Journal of labelled compoundsradiopharmaceuticals.
We report here the detailed radiosynthesis of [
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b9c4028f5cdb7f13f4d03a8a6f87bbd
https://pubmed.ncbi.nlm.nih.gov/36593743
https://pubmed.ncbi.nlm.nih.gov/36593743
Publikováno v:
Applied Thermal Engineering. 225:120074
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7e6266d3b9c599f30b9214085f6884e
https://doi.org/10.1016/j.applthermaleng.2023.120074
https://doi.org/10.1016/j.applthermaleng.2023.120074
Autor:
Hye Jin Kang, Maeva Dhaynaut, Nicolas Guehl, Zhaoda Zhang, Baohui Zheng, Anna-Liisa Brownell, Georges El Fakhri, Sung-Hyun Moon, Gengyang Yuan, Marc D. Normandin, Xiying Qu, Timothy M. Shoup, Sepideh Afshar
Publikováno v:
Molecular Imaging and Biology. 23:527-536
Metabotropic glutamate receptor 2 (mGluR2) has been implicated in various psychiatric and neurological disorders, such as schizophrenia and Alzheimer’s disease. We have previously developed [11C]7 as a PET radioligand for imaging mGluR2. Herein, [1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db2a484c06688829614a4d2051c9f1da
https://doi.org/10.1007/s11307-021-01586-0
https://doi.org/10.1007/s11307-021-01586-0
Autor:
Junfeng Wang, Kazue Takahashi, Timothy M. Shoup, Lichong Gong, Yingbo Li, Georges El Fakhri, Zhaoda Zhang, Anna-Liisa Brownell
Publikováno v:
Bioorg Chem
A novel organomediated cleavage of benzoyl group using ethane-1,2-diamine and acetic acid under neutral condition enables an efficient synthesis of 1-(6-nitropyridin-2-yl)thiourea, which previously has been challenging to prepare by conventional meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a5f1a50847f13bb16254265fbd5c98
https://europepmc.org/articles/PMC9189786/
https://europepmc.org/articles/PMC9189786/
Autor:
Timothy M. Shoup, Chuzhi Pan, Ji-Kyung Choi, Sepideh Afshar, Junfeng Wang, Aijun Zhu, Xiying Qu, Hye Jin Kang, Pekka Poutiainen, Zhaoda Zhang, Anna-Liisa Brownell, Georges El Fakhri, Gengyang Yuan
Publikováno v:
Journal of Medicinal Chemistry. 63:3381-3389
We have synthesized and characterized [18F]-N-(4-chloro-3-((fluoromethyl-d2)thio)phenyl)-picolinamide ([18F]15) as a potential ligand for the positron emission tomography (PET) imaging of mGluR4 in the brain. Radioligand [18F]15 displays central nerv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b66cfdecbcbb01348dc3d7f53268e98d
https://doi.org/10.1021/acs.jmedchem.0c00201
https://doi.org/10.1021/acs.jmedchem.0c00201
Publikováno v:
Tetrahedron. 75:3917-3922
Recently [11C]mG4P012 (previously [11C]KALB012 and presently named as [11C]PXT012253 by Prexton Therapeutics) had been used as a biomarker during the preclinical development of a potential therapeutic drug, PXT0002331 (an mGluR4 PAM), for PD and l -d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2453f849ab87761acf6db0c5064d5138
https://doi.org/10.1016/j.tet.2019.06.010
https://doi.org/10.1016/j.tet.2019.06.010