Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Zhaochen Ning"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
In recent studies, NKG2A is revealed to be a key immune checkpoint for both natural killer (NK) cells and CD8+ T cells. It form heterodimer receptors with CD94, and targets the peptide-presenting human leukocyte antigen-E (HLA-E) molecules. Upon cros
Externí odkaz:
https://doaj.org/article/46525ff3cb194b9298eb80dbcb752bed
Autor:
Xin Zhang, Yonghong Yang, Lina Jing, Weiwei Zhai, Hui Zhang, Qun Ma, Chunxia Li, Fenglian Yan, Dalei Cheng, Junfeng Zhang, Zhaochen Ning, Hui Shi, Changying Wang, Mingsheng Zhao, Jun Dai, Zhihua Li, Jiankuo Ming, Meimei Yu, Haiyan Wang, Hongyan Cheng, Huabao Xiong, Guanjun Dong
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Toll-like receptors (TLRs) play critical roles in regulating the abnormal activation of the immune cells resulting in the pathogenesis of inflammation and autoimmune diseases. Pyruvate kinase M2 (PKM2), which governs the last step of glycolysis, is i
Externí odkaz:
https://doaj.org/article/a5699781b3aa4c7f978f7872a47d4c5f
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
B and T lymphocyte attenuator (BTLA) is one of the most important cosignaling molecules. It belongs to the CD28 superfamily and is similar to programmed cell death-1 (PD-1) and cytotoxic T lymphocyte associated antigen-4 (CTLA-4) in terms of its stru
Externí odkaz:
https://doaj.org/article/0c910285f14b4df8a843de1393a8d462
Autor:
Xuehui Li, Xiaoying Yao, Yuzhen Zhu, Hui Zhang, Haiyan Wang, Qun Ma, Fenglian Yan, Yonghong Yang, Junfeng Zhang, Hui Shi, Zhaochen Ning, Jun Dai, Zhihua Li, Chunxia Li, Fei Su, Yin Xue, Xiangzhi Meng, Guanjun Dong, Huabao Xiong
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Macrophages play a critical role in the pathogenesis of endotoxin shock by producing excessive amounts of pro-inflammatory cytokines. A pan-caspase inhibitor, zVAD, can be used to induce necroptosis under certain stimuli. The role of zVAD in both reg
Externí odkaz:
https://doaj.org/article/2bde2b71bd3b4a95b4db182eb3d22468
Autor:
Xiaoying Yao, Guanjun Dong, Yuzhen Zhu, Fenglian Yan, Hui Zhang, Qun Ma, Xingqin Fu, Xuehui Li, QingQing Zhang, Junfeng Zhang, Hui Shi, Zhaochen Ning, Jun Dai, Zhihua Li, Chunxia Li, Bo Wang, Jiankuo Ming, Yonghong Yang, Feng Hong, Xiangzhi Meng, Huabao Xiong, Chuanping Si
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Dysregulation of macrophage has been demonstrated to contribute to aberrant immune responses and inflammatory diseases. CD11b, expressed on macrophages, plays a critical role in regulating pathogen recognition, phagocytosis, and cell survival. In the
Externí odkaz:
https://doaj.org/article/4069320008be4c649ab1f3befa21c853
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Shuxuening injection (SXNI) is a widely prescribed herbal medicine of Ginkgo biloba extract (EGB) for cerebral and cardiovascular diseases in China. However, its curative effects on ischemic stroke and heart diseases and the underlying mechanisms rem
Externí odkaz:
https://doaj.org/article/f4ddbd6f868c467f9012b396c2e0d0e3
Autor:
Chunxia Li, Jun Dai, Chuanbin Liu, Guanjun Dong, Xin Zhang, Junfeng Zhang, Fenglian Yan, Hui Zhang, Changying Wang, Mingsheng Zhao, Zhaochen Ning, Qun Ma, Hui Shi, Zhihua Li, Huabao Xiong
Publikováno v:
Inflammation. 46:418-431
Endotoxin shock remains one of the major causes of mortality worldwide. Pyruvate dehydrogenase kinase (PDK) 2 is an important regulatory enzyme involved in glucose metabolism. The purpose of this study was to determine the regulatory effect of PDK2 o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cb4fa2f5a16b3d7dc717079a6218591
https://doi.org/10.1007/s10753-022-01744-8
https://doi.org/10.1007/s10753-022-01744-8
Autor:
Junfeng Zhang, Yunsheng Zhang, Zhiya Yang, Dalei Cheng, Hui Zhang, Li Wei, Chen Liu, Jia Fu, Fenglian Yan, Chunxia Li, Guanjun Dong, Hui Shi, Zhaochen Ning, Changying Wang, Mingsheng Zhao, Jun Dai, Dongmei Shi, Huabao Xiong
Background and Purpose: Psoriasis is an immune-associated disease, however, the pathogenesis of psoriasis remains unclear. We investigated the mechanism of IL-35 in psoriasis treatment. Experimental Approach: PASI and Baker scores were used to evalua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5a51ad9c52bc7f444430078619e6664
https://doi.org/10.22541/au.164407908.87135419/v1
https://doi.org/10.22541/au.164407908.87135419/v1
Autor:
Hui Shi, Jing Hu, Minghui Liu, Xingna Bao, Chenjie Liu, Zhaochen Ning, Guanjun Dong, Junfeng Zhang, Jia Fu, Bin Xiong
Publikováno v:
Journal of Cellular and Molecular Medicine
Long non‐coding RNA MIR503 host gene (MIR503HG) is located on chromosome Xq26.3, and has been found to be deregulated in many types of human malignancy and function as tumour suppressor or promoter based on cancer types. The role of MIR503HG in bre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1712b5ed986af823037688a575d4fea
https://doi.org/10.1111/jcmm.14344
https://doi.org/10.1111/jcmm.14344
Autor:
Hui Zhang, Cuiling Wang, Fenglian Yan, Chunxia Li, Jiankuo Ming, Yonghong Yang, Yuan Hu, Jun Dai, Guanjun Dong, Chuanping Si, Yuzhen Zhu, Zhaochen Ning, Xiaoying Yao, Qun Ma, Huabao Xiong, Zhihua Li, Xuehui Li, Hui Shi, Junfeng Zhang, Panpan Cheng
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1865:535-546
Myeloid-derived suppressor cells (MDSCs) play an immunosuppressive role in the pathogenesis of inflammatory diseases. CD180, a TLR-like protein, can regulate the proliferation and activation of immune cells. However, the roles of CD180 in regulating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c544034dd29e5817697a2a15d83e110
https://doi.org/10.1016/j.bbadis.2018.12.013
https://doi.org/10.1016/j.bbadis.2018.12.013