Zobrazeno 1 - 10
of 292
pro vyhledávání: '"Zhao-Rong Lun"'
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Trichomoniasis caused by Trichomonas vaginalis is the most prevalent nonviral sexually transmitted disease in women and has frequently damaged public health. To better use the animal model and take a step forward fully elucidating
Externí odkaz:
https://doaj.org/article/a8382d31266f425cb3b8ce4091fc0c7e
Autor:
Zhiqiang Hu, Yufen Zhang, Yingchao Xie, Jianwu Yang, Haotian Tang, Bolin Fan, Ke Zeng, Zhongxin Han, Jiansen Lu, Huaji Jiang, Wenqiang Peng, Hongyu Li, Huadan Chen, Sha Wu, Bang Shen, Zhao‐Rong Lun, Xiao Yu
Publikováno v:
Advanced Science, Vol 11, Iss 32, Pp n/a-n/a (2024)
Abstract Toxoplasma gondii (T. gondii)‐associated polymorphic effector proteins are crucial in parasite development and regulating host anti‐T. gondii immune responses. However, the mechanism remains obscure. Here, it is shown that Toxoplasma eff
Externí odkaz:
https://doaj.org/article/3224cdbd7623472b8286a1e7eec3935b
Autor:
Siyu Zhao, Yunyi Hu, Bicheng Yang, Lichao Zhang, Meiyining Xu, Kefeng Jiang, Zhun Liu, Mingrou Wu, Yun Huang, Peipei Li, Si-Jia Liang, Xi Sun, Geoff Hide, Zhao-Rong Lun, Zhongdao Wu, Jia Shen
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The anti-foreign tissue (transplant rejection) response, mediated by the immune system, has been the biggest obstacle to successful organ transplantation. There are still many enigmas regarding this process and some aspects of the underlying
Externí odkaz:
https://doaj.org/article/5cb2e6c9ee544175ba96af93dd6f01e6
Autor:
Hui Dong, Jiong Yang, Kai He, Wen-Bin Zheng, De-Hua Lai, Jing Liu, Hui-Yong Ding, Rui-Bin Wu, Kevin M Brown, Geoff Hide, Zhao-Rong Lun, Xing-Quan Zhu, Shaojun Long
Publikováno v:
eLife, Vol 12 (2024)
The apicoplast is a four-membrane plastid found in the apicomplexans, which harbors biosynthesis and organelle housekeeping activities in the matrix. However, the mechanism driving the flux of metabolites, in and out, remains unknown. Here, we used T
Externí odkaz:
https://doaj.org/article/8397a5d62a4d4a6b99f4c420622439eb
Autor:
Jia Shen, Siyu Zhao, Mei Peng, Yanguo Li, Lichao Zhang, Xiaoping Li, Yunyi Hu, Mingrou Wu, Suoyu Xiang, Xiaoying Wu, Jiahua Liu, Beibei Zhang, Zebin Chen, Datao Lin, Huanyao Liu, Wenyan Tang, Jun Chen, Xi Sun, Qi Liao, Geoff Hide, Zhijun Zhou, Zhao-Rong Lun, Zhongdao Wu
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-21 (2023)
Abstract Schistosoma parasites, causing schistosomiasis, exhibit typical host specificity in host preference. Many mammals, including humans, are susceptible to infection, while the widely distributed rodent, Microtus fortis, exhibits natural anti-sc
Externí odkaz:
https://doaj.org/article/16c888a22e6441728ae6f69087dc4657
Autor:
Yang Sun, Zi-Liang Huang, Wen-Xin Chen, Yi-Feng Zhang, Hao-Tian Lei, Qiao-Juan Huang, Zhao-Rong Lun, Liang-Hu Qu, Ling-Ling Zheng
Publikováno v:
Biomolecules, Vol 14, Iss 5, p 516 (2024)
Viruses are obligate intracellular parasites that rely on cell surface receptor molecules to complete the first step of invading host cells. The experimental method for virus receptor screening is time-consuming, and receptor molecules have been iden
Externí odkaz:
https://doaj.org/article/4087f0828a894dd4a165164463b63f7f
Autor:
Wenyan Wan, Hui Dong, De-Hua Lai, Jiong Yang, Kai He, Xiaoyan Tang, Qun Liu, Geoff Hide, Xing-Quan Zhu, L. David Sibley, Zhao-Rong Lun, Shaojun Long
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Toxoplasma gondii acquires host cytosolic materials, yet the mechanism remains unknown. Wan et al. reveal the micropore as an essential organelle at the plasma membrane for endocytosis of host cytosolic proteins and biotin, and Golgi ceramide.
Externí odkaz:
https://doaj.org/article/c20394fc9378424aad96f749b94f2e74
Autor:
Qiang-Qiang Wang, Ming Sun, Tao Tang, De-Hua Lai, Jing Liu, Sanjay Maity, Kai He, Xi-Ting Wu, Jiong Yang, Yue-Bao Li, Xiao-Yan Tang, Hui-Yong Ding, Geoff Hide, Mark Distefano, Zhao-Rong Lun, Xing-Quan Zhu, Shaojun Long
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT In the apicomplexans, endocytosed cargos (e.g., hemoglobin) are trafficked to a specialized organelle for digestion. This follows a unique endocytotic process at the micropore/cytostome in these parasites. However, the mechanism underlying e
Externí odkaz:
https://doaj.org/article/402a8b5207a94fc08108a12515f8837f
Autor:
Lei Chen, Wei-Jie Guan, Zhuo-Er Qiu, Jian-Bang Xu, Xu Bai, Xiao-Chun Hou, Jing Sun, Su Qu, Ze-Xin Huang, Tian-Lun Lei, Zi-Yang Huang, Jincun Zhao, Yun-Xin Zhu, Ke-Nan Ye, Zhao-Rong Lun, Wen-Liang Zhou, Nan-Shan Zhong, Yi-Lin Zhang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-13 (2022)
Abstract SARS-CoV-2, the culprit pathogen of COVID-19, elicits prominent immune responses and cytokine storms. Intracellular Cl− is a crucial regulator of host defense, whereas the role of Cl− signaling pathway in modulating pulmonary inflammatio
Externí odkaz:
https://doaj.org/article/28be0a15ff0f49bbb05bc30cddee7ff7
Publikováno v:
Advanced Science, Vol 10, Iss 14, Pp n/a-n/a (2023)
Abstract Toxoplasma gondii (T. gondii) is the causative agent of toxoplasmosis and can infect numerous warm‐blooded animals. An improved understanding of the fine structure of this parasite can help elucidate its replication mechanism. Previous stu
Externí odkaz:
https://doaj.org/article/8343fc45efd64bd894b73ff8a31b7888