Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Zhao Zhi Boo"'
Autor:
Xiangke Duan, Zhao Zhi Boo, Song Lin Chua, Kelvin Han Chung Chong, Ziqi Long, Renliang Yang, Yachun Zhou, Baptiste Janela, Sanjay Haresh Chotirmall, Florent Ginhoux, Qinghua Hu, Bin Wu, Liang Yang
Publikováno v:
Advanced Science, Vol 10, Iss 34, Pp n/a-n/a (2023)
Abstract Innate immune adaptor proteins are critical components of the innate immune system that propagate pro‐inflammatory responses from their upstream receptors, and lead to pathogen clearance from the host. Bacterial pathogens have developed st
Externí odkaz:
https://doaj.org/article/4e8ea68e570547e187ffb265bbfa4002
Autor:
Qin Gong, Kim Robinson, Chenrui Xu, Phuong Thao Huynh, Kelvin Han Chung Chong, Eddie Yong Jun Tan, Jiawen Zhang, Zhao Zhi Boo, Daniel Eng Thiam Teo, Kenneth Lay, Yaming Zhang, John Soon Yew Lim, Wah Ing Goh, Graham Wright, Franklin L. Zhong, Bruno Reversade, Bin Wu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
NLRP1 and CARD8 are two recently described sensor proteins for the human inflammasome complex. Here, the authors present the cryo-EM CARD filament structures of the NLRP1 and CARD8 activating domains, which reveal how NLRP1 and CARD8 discriminate bet
Externí odkaz:
https://doaj.org/article/fb33e8feb690411b8e3bbd80f9119b57
Autor:
Qin Gong, Ziqi Long, Franklin L. Zhong, Daniel Eng Thiam Teo, Yibo Jin, Zhan Yin, Zhao Zhi Boo, Yaming Zhang, Jiawen Zhang, Renliang Yang, Shashi Bhushan, Bruno Reversade, Zongli Li, Bin Wu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The pathogen recognition receptors NOD1/2 recognize bacterial cell wall components and signal through their downstream adapter kinase RIP2 via a CARD (Caspase activation and recruitment domain) mediated oligomerization process. Here the authors prese
Externí odkaz:
https://doaj.org/article/c29ed6dc071e4abb9215cc7c527e42b9
Autor:
Joey Kuok Hoong Yam, Thet Tun Aung, Song Lin Chua, Yingying Cheng, Gurjeet Singh Kohli, Jianuan Zhou, Florentin Constancias, Yang Liu, Zhao Cai, May Margarette Santillan Salido, Daniela I. Drautz-Moses, Scott A. Rice, Stephan Christoph Schuster, Zhao Zhi Boo, Bin Wu, Staffan Kjelleberg, Tim Tolker-Nielsen, Rajamani Lakshminarayanan, Roger W. Beuerman, Liang Yang, Michael Givskov
Publikováno v:
Infection and immunity, 90 (8)
Yam, J K H, Aung, T T, Chua, S L, Cheng, Y, Kohli, G S, Zhou, J, Constancias, F, Liu, Y, Cai, Z, Salido, M M S, Drautz-Moses, D I, Rice, S A, Schuster, S C, Boo, Z Z, Wu, B, Kjelleberg, S, Tolker-Nielsen, T, Lakshminarayanan, R, Beuerman, R W, Yang, L & Givskov, M 2022, ' Elevated c-di-GMP Levels and Expression of the Type III Secretion System Promote Corneal Infection by Pseudomonas aeruginosa ', Infection and Immunity, vol. 90, no. 8 . https://doi.org/10.1128/iai.00061-22
Yam, J K H, Aung, T T, Chua, S L, Cheng, Y, Kohli, G S, Zhou, J, Constancias, F, Liu, Y, Cai, Z, Salido, M M S, Drautz-Moses, D I, Rice, S A, Schuster, S C, Boo, Z Z, Wu, B, Kjelleberg, S, Tolker-Nielsen, T, Lakshminarayanan, R, Beuerman, R W, Yang, L & Givskov, M 2022, ' Elevated c-di-GMP Levels and Expression of the Type III Secretion System Promote Corneal Infection by Pseudomonas aeruginosa ', Infection and Immunity, vol. 90, no. 8 . https://doi.org/10.1128/iai.00061-22
Pseudomonas aeruginosa is generally believed to establish biofilm-associated infections under the regulation of the secondary messenger c-di-GMP. To evaluate P. aeruginosa biofilm physiology during ocular infections, comparative transcriptomic analys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faabfddccbc986ff3c6cef4e563402a5
https://hdl.handle.net/10453/164130
https://hdl.handle.net/10453/164130
Autor:
Yaming Zhang, Franklin L. Zhong, Chenrui Xu, Zhao Zhi Boo, Kim S. Robinson, Bruno Reversade, Daniel Eng Thiam Teo, Kenneth Lay, Jiawen Zhang, Graham D. Wright, John Soon Yew Lim, Eddie Yong Jun Tan, Kelvin Han Chung Chong, Wah Ing Goh, Qin Gong, Phuong Thao Huynh, Bin Wu
Publikováno v:
Nature communications, 12(1):188. Nature Publishing Group
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nod-like receptor (NLR) proteins activate pyroptotic cell death and IL-1 driven inflammation by assembling and activating the inflammasome complex. Closely related sensor proteins NLRP1 and CARD8 undergo unique auto-proteolysis-dependent activation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::971fea044a57af53224281deaea2a5a9
https://pure.amc.nl/en/publications/structural-basis-for-distinct-inflammasome-complex-assembly-by-human-nlrp1-and-card8(f93492eb-c2e0-49e8-a33d-9316ae5981a5).html
https://pure.amc.nl/en/publications/structural-basis-for-distinct-inflammasome-complex-assembly-by-human-nlrp1-and-card8(f93492eb-c2e0-49e8-a33d-9316ae5981a5).html
Autor:
Franklin L. Zhong, Bruno Reversade, Daniel Eng Thiam Teo, Yibo Jin, Qin Gong, Jiawen Zhang, Zhan Yin, Bin Wu, Zongli Li, Yaming Zhang, Zhao Zhi Boo, Renliang Yang, Long Ziqi, Shashi Bhushan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature communications, 9(1):4993. Nature Publishing Group
Nature Communications
Nature communications, 9(1):4993. Nature Publishing Group
Nature Communications
Signals arising from bacterial infections are detected by pathogen recognition receptors (PRRs) and are transduced by specialized adapter proteins in mammalian cells. The Receptor-interacting-serine/threonine-protein kinase 2 (RIPK2 or RIP2) is such
Autor:
Kim S. Robinson, John Soon Yew Lim, Franklin L. Zhong, Chenrui Xu, Bin Wu, Bruno Reversade, Daniel Eng Thiam Teo, Jiawen Zhang, Qin Gong, Graham D. Wright, Wah Ing Goh, Yaming Zhang, Zhao Zhi Boo
Nod-like receptor (NLR) proteins activate pyroptotic cell death and IL-1 driven inflammation by assembling and activating the inflammasome complex. Closely related NLR proteins, NLRP1 and CARD8 undergo unique auto-proteolysis-dependent activation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4fe4bb4cd9fbbcea40bf985e8835d4e
https://doi.org/10.1101/2020.06.17.156307
https://doi.org/10.1101/2020.06.17.156307
Autor:
Liang Yang, Michael Givskov, July Fong, Wu Bin, Chaodong Zhang, Renliang Yang, Xue-Wei Liu, Soon Keat Tan, Thomas E. Nielsen, Haibin Su, Zhao Zhi Boo
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Fong, J, Zhang, C, Yang, R, Boo, Z Z, Tan, S K, Nielsen, T E, Givskov, M, Liu, X-W, Bin, W, Su, H & Yang, L 2018, ' Combination Therapy Strategy of Quorum Quenching Enzyme and Quorum Sensing Inhibitor in Suppressing Multiple Quorum Sensing Pathways of P. aeruginosa ', Scientific Reports, vol. 8, 1155 . https://doi.org/10.1038/s41598-018-19504-w
Scientific Reports
Fong, J, Zhang, C, Yang, R, Boo, Z Z, Tan, S K, Nielsen, T E, Givskov, M, Liu, X-W, Bin, W, Su, H & Yang, L 2018, ' Combination Therapy Strategy of Quorum Quenching Enzyme and Quorum Sensing Inhibitor in Suppressing Multiple Quorum Sensing Pathways of P. aeruginosa ', Scientific Reports, vol. 8, 1155 . https://doi.org/10.1038/s41598-018-19504-w
Scientific Reports
The threat of antibiotic resistant bacteria has called for alternative antimicrobial strategies that would mitigate the increase of classical resistance mechanism. Many bacteria employ quorum sensing (QS) to govern the production of virulence factors
Autor:
Liang Yang, Bin Wu, Michael Givskov, Thomas E. Nielsen, Renliang Yang, Chaodong Zhang, Soon Keat Tan, July Fong, Zhao Zhi Boo, Haibin Su
The threat of antibiotic resistant bacteria has called for alternative antimicrobial strategies that would mitigate the increase of classical resistance mechanism. Many bacteria employ quorum sensing (QS) to govern the production of virulence genes a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b137bcaba42a6338d8011978064ef2