Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Zhao Hui Wu"'
Publikováno v:
Jichu yixue yu linchuang, Vol 41, Iss 1, Pp 130-134 (2021)
Objective To explore and practice“rain classroom” in basic medical teaching. Methods Take the undergraduates majoring in Imaging Technology and Biotechnology in the class of 2018 of Dalian Medical University as the research objects Through questi
Externí odkaz:
https://doaj.org/article/5011cf365aeb4801b5e0fcae9fd305c8
Autor:
Wei Wang, Zhao-Hui Wu
Publikováno v:
Genes and Diseases, Vol 8, Iss 1, Pp 1-5 (2021)
Ultraviolet radiation (UVR) is a prominent etiological factor of the pathogenesis of skin diseases such as squamous cell carcinoma and melanoma. Excessive exposure to the natural sources of UVR such as sunlight or artificially from tanning lamps has
Externí odkaz:
https://doaj.org/article/b696c0b6330c4d4f9fc5831b43bd29b3
Autor:
Wei Wang, Mingqi Li, Suriyan Ponnusamy, Yayun Chi, Jingyan Xue, Beshoy Fahmy, Meiyun Fan, Gustavo A. Miranda-Carboni, Ramesh Narayanan, Jiong Wu, Zhao-Hui Wu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Genotoxic agents have been shown to activate the Wnt/β-catenin signaling but the underlying mechanism remains unclear. Here, the authors show that upon DNA damage, the deubiquitinase OTULIN activates Wnt/β-catenin signaling by inhibiting linear ubi
Externí odkaz:
https://doaj.org/article/b4496d310ec64236a21571f5bea2d9bf
Autor:
Yang Shen, Mehari Endale, Wei Wang, Andrew R Morris, Lauren J Francey, Rachel L Harold, David W Hammers, Zhiguang Huo, Carrie L Partch, John B Hogenesch, Zhao-Hui Wu, Andrew C Liu
Publikováno v:
PLoS Genetics, Vol 17, Iss 11, p e1009933 (2021)
In mammals, the circadian clock coordinates cell physiological processes including inflammation. Recent studies suggested a crosstalk between these two pathways. However, the mechanism of how inflammation affects the clock is not well understood. Her
Externí odkaz:
https://doaj.org/article/8c322ffad905458f9004ba7659bb8655
Autor:
Bingqiu Xiu, Yayun Chi, Lei Liu, Weiru Chi, Qi Zhang, Jiajian Chen, Rong Guo, Jing Si, Lun Li, Jingyan Xue, Zhi-Ming Shao, Zhao-Hui Wu, Shenglin Huang, Jiong Wu
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-20 (2019)
Abstract Background The majority of breast cancer patients die of metastasis rather than primary tumors, whereas the molecular mechanisms orchestrating cancer metastasis remains poorly understood. Long noncoding RNAs (lncRNA) have been shown to regul
Externí odkaz:
https://doaj.org/article/d8113f2c63234be3b86df43c48562a53
Autor:
Wei Wang, Zhao-Hui Wu
Publikováno v:
Molecular & Cellular Oncology, Vol 7, Iss 6 (2020)
Oncogenic Wnt/β-catenin activation promotes cancer development and drug resistance to cancer treatments. We recently revealed an underlying mechanism linking linear ubiquitination with Wnt/β-catenin activation upon genotoxic treatments. We showed t
Externí odkaz:
https://doaj.org/article/81c271b1839149c3a03e35b12feb1a06
Autor:
Aarti Sethuraman, Martin Brown, Raya Krutilina, Zhao-Hui Wu, Tiffany N. Seagroves, Lawrence M. Pfeffer, Meiyun Fan
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-17 (2018)
Abstract Background Metastasis is responsible for a significant number of breast cancer-related deaths. Hypoxia, a primary driving force of cancer metastasis, induces the expression of BHLHE40, a transcription regulator. This study aimed to elucidate
Externí odkaz:
https://doaj.org/article/988b28cb573942f08a89ec7b374d82d1
Publikováno v:
In Procedia Engineering 2017 174:800-807
Autor:
Zhao-Hui Wu, Hongbo Chi, Lawrence M. Pfeffer, M. Raza Zaidi, R. Nicholas Laribee, Meiyun Fan, Mingqi Li, Bo Zhang, Nicole M. Chapman, Wei Wang
UVB-induced NF-kB activation is independent of p38, CK2, TAK1 and DDR kinases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::584789f53c935304607af25dd2cf0a1a
https://doi.org/10.1158/0008-5472.22421517
https://doi.org/10.1158/0008-5472.22421517
Autor:
Zhao-Hui Wu, Hongbo Chi, Lawrence M. Pfeffer, M. Raza Zaidi, R. Nicholas Laribee, Meiyun Fan, Mingqi Li, Bo Zhang, Nicole M. Chapman, Wei Wang
Solar ultraviolet radiation (UVR) suppresses skin immunity, which facilitates initiation of skin lesions and establishment of tumors by promoting immune evasion. It is unclear whether immune checkpoints are involved in the modulation of skin immunity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::285d54b065abb4534e1d6884383c0535
https://doi.org/10.1158/0008-5472.c.6510951.v1
https://doi.org/10.1158/0008-5472.c.6510951.v1