Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Zhao‐Jia Ge"'
Effects of multisuperovulation on the transcription and genomic methylation of oocytes and offspring
Autor:
Juan-Ke Xie, Qian wang, Yuan-Hui Chen, Shou-Bin Tang, Hao-Yue Sun, Zhao-Jia Ge, Cui-Lian Zhang
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background Controlled ovarian stimulation is a common skill of assisted reproductive technologies (ARTs). In the clinic, some females would undergo more than one controlled ovarian stimulation cycle. However, few studies have focused on the
Externí odkaz:
https://doaj.org/article/b5352d1ad4f14f45a34ce8b2ee3163b4
Autor:
Shou-Bin Tang, Ting-Ting Zhang, Shen Yin, Wei Shen, Shi-Ming Luo, Yong Zhao, Cui-Lian Zhang, Francesca Gioia Klinger, Qing-Yuan Sun, Zhao-Jia Ge
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Undernourishment in utero has deleterious effects on the metabolism of offspring, but the mechanism of the transgenerational transmission of metabolic disorders is not well known. In the present study, we found that undernourishme
Externí odkaz:
https://doaj.org/article/d1304c919b434eefbeac82a8fe3d2a70
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/a071dfae378046a1ab8c3fdf935d40a0
Autor:
Qian Wang, Shu-Xian Zhao, Jian-Ning He, Hua Zhao, Bao-Xia Gu, Juan-Ke Xie, Yi-Jun Zhao, Cui-Lian Zhang, Zhao-Jia Ge
Publikováno v:
Cells, Vol 12, Iss 1, p 92 (2022)
For humans, ARTs (assisted reproductive technologies) have become the most effective method to treat subfertility/infertility in clinic. To obtain enough oocytes during ART, ovarian stimulation is performed by exogenous hormones, and some patients un
Externí odkaz:
https://doaj.org/article/1be22ea27c6b424091a310adabbb4267
Autor:
Yan-Li Sun, Xue-Lin Wang, Lei-Lei Yang, Zhao-Jia Ge, Yong Zhao, Shi-Ming Luo, Wei Shen, Qing-Yuan Sun, Shen Yin
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Paraquat (PQ) is a widely used non-selective and oxidizing herbicide in farmland, orchards, flower nursery, and grassland. Overuse of PQ will accumulate in the body and affect the reproduction in mammals. In this study, we found that PQ could reduce
Externí odkaz:
https://doaj.org/article/158daa38bd6d4be8a3183d8f657e85e5
Autor:
Ning Song, Nameun Kim, Rui Xiao, Hojun Choi, Hyo-Im Chun, Min-Hee Kang, Jin-Hoi Kim, Kunho Seo, Nagasundarapandian Soundrarajan, Jeong-Tae Do, Hyuk Song, Zhao-Jia Ge, Chankyu Park
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139557 (2015)
Females homozygous for the Purkinje cell degeneration mutation (pcd) are fertile, although the success rate is much lower than in the wild type. We performed detailed analysis of reproductive abnormalities of pcd females. The number of oocytes produc
Externí odkaz:
https://doaj.org/article/cb97f83d43d8460e9d77e3488ce0f69f
Autor:
Jun-Yu Ma, Mo Li, Zhao-Jia Ge, Yibo Luo, Xiang-Hong Ou, Shuhui Song, Dongmei Tian, Jin Yang, Bing Zhang, Ying-Chun Ou-Yang, Yi Hou, Zhonghua Liu, Heide Schatten, Qing-Yuan Sun
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41981 (2012)
In mouse ovarian follicles, granulosa cells but not oocytes take up glucose to provide the oocyte with nourishments for energy metabolism. Diabetes-induced hyperglycemia or glucose absorption inefficiency consistently causes granulosa cell apoptosis
Externí odkaz:
https://doaj.org/article/91ea676dfc7049c5a32651607c10e077
Autor:
Yanchang Wei, Saima Multi, Cai-Rong Yang, Junyu Ma, Qing-Hua Zhang, Zhen-Bo Wang, Mo Li, Liang Wei, Zhao-Jia Ge, Chun-Hui Zhang, Ying-Chun Ouyang, Yi Hou, Heide Schatten, Qing-Yuan Sun
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21557 (2011)
Errors in chromosome segregation or distribution may result in aneuploid embryo formation, which causes implantation failure, spontaneous abortion, genetic diseases, or embryo death. Embryonic aneuploidy occurs when chromosome aberrations are present
Externí odkaz:
https://doaj.org/article/f88f9cf1812f4d6d9d3256e70ceba006
Autor:
Xiao-Yan Fan, Lei Guo, Lei-Ning Chen, Shen Yin, Jiarong Wen, Sen Li, Jun-Yu Ma, Tao Jing, Man-Xi Jiang, Xiao-Hong Sun, Meilan Chen, Feng Wang, Zhen-Bo Wang, Chang-Fa Zhang, Xing-Hua Wang, Zhao-Jia Ge, Chun Hu, Lizhang Zeng, Wei Shen, Qing-Yuan Sun, Xiang-Hong Ou, Shi-Ming Luo
Publikováno v:
Nature Biomedical Engineering. 6:339-350
Mitochondrial replacement therapy (MRT) has been used to prevent maternal transmission of disease-causing mutations in mitochondrial DNA (mtDNA). However, because MRT requires nuclear transfer, it carries the risk of mtDNA carryover and hence of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d1dbf83e2429ddce90f7c6151b9cb9
https://doi.org/10.1038/s41551-022-00881-7
https://doi.org/10.1038/s41551-022-00881-7
Autor:
Jun Lu, Shu-Xian Zhao, Man-Yu Zhang, Peng-Yuan Ji, Shuo Chao, Li-Jun Li, Shen Yin, Lei Zhao, Hua Zhao, Qing-Yuan Sun, Zhao-Jia Ge
Publikováno v:
Food & Function. 13:5396-5405
Maternal diabetes mellitus reduces oocyte quality, such as abnormalities of spindle assembly and chromosome segregation, mitochondrial dysfunction, decrease of fertilization rate, increase of ROS, and so on. So, it is important to research how to res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f98741f6b7fb4dbe68592cb95a0f225f
https://doi.org/10.1039/d1fo03770f
https://doi.org/10.1039/d1fo03770f