Exosome transportation-mediated immunosuppression relief through cascade amplification for enhanced apoptotic body vaccination

Autor: Zhao, Gaoqian, Liu, Huifang, Wang, Zhaoshuo, Yang, Hua, Zhao, Huiqing, Zhang, Yixin, Ge, Kun, Wang, Xueyi, Luo, Li, Zhou, Xiaohan, Zhang, Jinchao, Li, Zhenhua

Publikováno v: In Acta Biomaterialia November 2022 153:529-539

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Therapeutic exosomal vaccine for enhanced cancer immunotherapy by mediating tumor microenvironment.

Autor: Lv F; College of Pharmaceutical Science, Key Laboratory of Pharmaceutical Quality Control of Hebei Province, Institute of Life Science and Green Development, Hebei University, Baoding 071002, China.; Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Chemical Biology Key Laboratory of Hebei Province, Hebei University, Baoding 071002, China., Liu H; College of Pharmaceutical Science, Key Laboratory of Pharmaceutical Quality Control of Hebei Province, Institute of Life Science and Green Development, Hebei University, Baoding 071002, China.; Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Chemical Biology Key Laboratory of Hebei Province, Hebei University, Baoding 071002, China., Zhao G; College of Pharmaceutical Science, Key Laboratory of Pharmaceutical Quality Control of Hebei Province, Institute of Life Science and Green Development, Hebei University, Baoding 071002, China.; Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Chemical Biology Key Laboratory of Hebei Province, Hebei University, Baoding 071002, China., Zhao E; College of Pharmaceutical Science, Key Laboratory of Pharmaceutical Quality Control of Hebei Province, Institute of Life Science and Green Development, Hebei University, Baoding 071002, China.; Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Chemical Biology Key Laboratory of Hebei Province, Hebei University, Baoding 071002, China., Yan H; Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Chemical Biology Key Laboratory of Hebei Province, Hebei University, Baoding 071002, China.; College of Chemistry & Environmental Science, Institute of Life Science and Green Development, Hebei University, Baoding 071002, China., Che R; Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Chemical Biology Key Laboratory of Hebei Province, Hebei University, Baoding 071002, China.; College of Chemistry & Environmental Science, Institute of Life Science and Green Development, Hebei University, Baoding 071002, China., Yang X; Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Chemical Biology Key Laboratory of Hebei Province, Hebei University, Baoding 071002, China.; College of Chemistry & Environmental Science, Institute of Life Science and Green Development, Hebei University, Baoding 071002, China., Zhou X; Affiliated Dongguan Hospital, Southern Medical University, Dongguan 523059, China., Zhang J; Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Chemical Biology Key Laboratory of Hebei Province, Hebei University, Baoding 071002, China.; College of Chemistry & Environmental Science, Institute of Life Science and Green Development, Hebei University, Baoding 071002, China., Liang XJ; CAS Key Laboratory for Biological Effects of Nanomaterials and Nanosafety National Center for Nanoscience and Technology, Beijing 100190, China., Li Z; Affiliated Dongguan Hospital, Southern Medical University, Dongguan 523059, China.

Publikováno v: IScience [iScience] 2021 Dec 18; Vol. 25 (1), pp. 103639. Date of Electronic Publication: 2021 Dec 18 (Print Publication: 2022).