Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Zhanzhan Li"'
Publikováno v:
Heliyon, Vol 10, Iss 9, Pp e30337- (2024)
The biological function and prognostic value of efferocytosis in cancer remains unclear. In this study, we systematically analysed the expression profiles and genetic variations of 50 efferocytosis-related regulator genes in 33 cancer types. Using da
Externí odkaz:
https://doaj.org/article/185473a5c32246e78b066565c780a681
Publikováno v:
Cancer Medicine, Vol 11, Iss 24, Pp 5129-5144 (2022)
Abstract Background Head and neck squamous cell carcinoma (HNSCC) is a life‐threatening disease with poor prognosis. Pyroptosis has been recently disclosed as a programmed cell death triggered by invasive infection, involved in cancer development.
Externí odkaz:
https://doaj.org/article/e1825c45608a4252a68fb1e97e6bade1
Autor:
Wenjun Cao, Luqi Xiong, Li Meng, Zhanzhan Li, Zhongliang Hu, Huo Lei, Jun Wu, Tao Song, Chao Liu, Rui Wei, Liangfang Shen, Jidong Hong
Publikováno v:
Heliyon, Vol 9, Iss 7, Pp e18310- (2023)
As many countries face an ageing population, the number of older patients with glioblastoma (GB) is increasing. Thus, there is an urgent need for prognostic models to aid in treatment decision-making and life planning. A total of 98 patients with iso
Externí odkaz:
https://doaj.org/article/3ddea2bf2e734146a5ddf440d0eb6437
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe biological function and prognosis roles of thymosin β(TMSB) 10 are still unclear in pan-cancer. MethodsWe retrieved The Cancer Genome Atlas and Genotype-tissue expression datasets to obtain the difference of TMSB10 expression between
Externí odkaz:
https://doaj.org/article/eb7871a64ff54b9db226aef151b1c0e5
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract Background Programmed cell death is an active and orderly form of cell death regulated by intracellular genes that plays an important role in the normal occurrence and development of the immune system, and pyroptosis has been found to be inv
Externí odkaz:
https://doaj.org/article/6c7310ef36b14ba4b163ca04cc7a5f04
Publikováno v:
Cell Death and Disease, Vol 13, Iss 3, Pp 1-14 (2022)
Abstract Nasopharyngeal carcinoma (NPC) is the most common primary malignancy arising from the epithelial cells of nasopharynx. CircTMTC1 is upregulated in NPC patients, but its role and molecular mechanism in NPC are unknown. Normal nasopharyngeal e
Externí odkaz:
https://doaj.org/article/b6de6aec9a0b48159144cc894d020900
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Using the Chinese Glioma Genome Atlas (training dataset) and The Cancer Genome Atlas (validation dataset), we found that low-grade gliomas can be divided into two molecular subclasses based on 30 pyroptosis genes. Cluster 1 presented higher
Externí odkaz:
https://doaj.org/article/fecb87e3bd3d448c8dc86c45d82de46a
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-11 (2021)
Abstract Radioresistance emerges as the major obstacle to nasopharyngeal carcinoma (NPC) treatment, further understanding of underlying mechanisms is necessary to overcome the radioresistance and improve the therapeutic effect. In this study, we firs
Externí odkaz:
https://doaj.org/article/e579c21ecd07431788d2477b89168eda
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Copper toxicity involves the destruction of mitochondrial metabolic enzymes, triggering an unusual mechanism of cell death called cuproptosis, which proposes a novel approach using copper toxicity to treat cancer. However, the biological function of
Externí odkaz:
https://doaj.org/article/f6a3be42be7e41728a949adb777390af
Autor:
Jinfeng Wang, Zhanzhan Li, Xiuling Ma, Lifeng Du, Zhen Jia, Xue Cui, Liqun Yu, Jing Yang, Liwen Xiao, Bing Zhang, Huimin Fan, Fangqing Zhao
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Here, the authors present a comparative analyses on vaginal and uterine microbiota in 1223 samples derived from 655 women with chronic endometritis, which, combined with animal experiments, characterize the microbial translocation in the female repro
Externí odkaz:
https://doaj.org/article/507fea95126f4872a6f85b7d3cdcbdf6