Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Zhanxia Zhang"'
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Reversing the hypoxic microenvironment of tumors is an important method to enhance the synergistic effect of tumor treatment. In this work, we developed the nanoparticles called Ce6@HGMOF, which consists of a photosensitizer (Ce6), glucose o
Externí odkaz:
https://doaj.org/article/03c641344e33467da5e16b70c2081cc7
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
With the deepening of people’s understanding of lung cancer, the research of lung cancer immunotherapy has gradually become the focus of attention. As we all know, the treatment of many diseases relies on the rich sources, complex and varied compos
Externí odkaz:
https://doaj.org/article/f16b9f2fddba4d8fac13a785d84233ff
Autor:
Guangtao Zhang, Zhaoyan Li, Jiahuan Dong, Weili Zhou, Zhanxia Zhang, Zujun Que, Xiaohong Zhu, Yan Xu, Nida Cao, Aiguang Zhao
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Epithelial-to-mesenchymal transition (EMT) is a pivotal cellular phenomenon involved in tumour metastasis and progression. In gastric cancer (GC), EMT is the main reason for recurrence and metastasis in postoperative patients. Aca
Externí odkaz:
https://doaj.org/article/0c31992d839647958ba307a0f325e70f
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Knocking down the oncogene ROC1 with siRNA inhibits the proliferation of cancer cells by suppressing the Neddylation pathway. However, methods for delivering siRNA in vivo to induce this high anticancer activity with low potential side effec
Externí odkaz:
https://doaj.org/article/79e4a881a55a4fbd8712ee03ccd0dc7d
Publikováno v:
Materials & Design, Vol 204, Iss , Pp 109648- (2021)
Knocking down the UBC12 with siRNA could significantly suppress the Neddylation pathway and result in an admirable anti-cancer effect. However, how to transport siRNA in vivo with low potential toxicity is an urgent problem to be solved. For enhancin
Externí odkaz:
https://doaj.org/article/cce335ca75d843e69efec35b1acf1bc9
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Cinobufagin is used as a traditional Chinese medicine for cancer therapy. However, it has some disadvantages, such as poor water solubility, short circulating half-life, and low bioavailability. In the present study, a targeted delivery and smart res
Externí odkaz:
https://doaj.org/article/146f608005294f70a5a124aada0af228
Autor:
Fan Xu, Minghua Li, Zujun Que, Mingliang Su, Wang Yao, Yu Zhang, Bin Luo, Yan Li, Zhanxia Zhang, Jianhui Tian
Publikováno v:
Journal of Materials Chemistry B. 11:3453-3472
Combined chemo-immuno-photothermal therapy based on ursolic acid/astragaloside IV-loaded hyaluronic acid-modified polydopamine nanomedicine is a promising strategy for the treatment of non-small cell lung cancer (NSCLC) metastasis.
Autor:
Yukun Chen, Zhenzhi Wang, Xiaofan Wang, Mingliang Su, Fan Xu, Lian Yang, Lijun Jia, Zhanxia Zhang
Publikováno v:
International journal of nanomedicine. 17
10-Hydroxycamptothecin (HCPT) is a natural plant alkaloid from Camptotheca that shows potent antitumor activity by targeting intracellular topoisomerase I. However, factors such as instability of the lactone ring and insolubility in water have limite
Publikováno v:
Journal of Materials Chemistry B. 8:655-665
Stimuli response or controlled release is a new research hotspot in nanomedicine; however, there is scarce research on organic nanomedicines with stimuli responses, which limits their practical biological applications. In addition, homoharringtonine
Publikováno v:
International journal of nanomedicine. 17
Mingliang Su,* Yukun Chen,* Lijun Jia, Zhanxia Zhang Cancer Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, Peopleâs Republic of China*These authors contributed equally to this work