Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Zhanwen Li"'
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
This study aimed to investigate the dose–response relationship of rocuronium administered based on skeletal muscle weight and to assess the feasibility of calculating rocuronium dosage by skeletal muscle weight in short surgeries for patients with
Externí odkaz:
https://doaj.org/article/216569d2eb38462d83f51e3c4b70c6db
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Despite increased early diagnosis and improved treatment in breast cancer (BRCA) patients, prognosis prediction is still a challenging task due to the disease heterogeneity. This study was to identify a novel gene signature that can accurate
Externí odkaz:
https://doaj.org/article/be8ce2b2a0c849f6be796267ae6eeaa0
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0226702 (2020)
Protein structures, usually visualized in various highly idealized forms focusing on the three-dimensional arrangements of secondary structure elements, can also be described as lists of interacting residues or atoms and visualized as two-dimensional
Externí odkaz:
https://doaj.org/article/fa8f95fea7984732b3a8791a61ffcf2e
Autor:
Ning Ao, Yanyan Liu, Hailiang Feng, Xiaocui Bian, Zhanwen Li, Bei Gu, Xiaomei Zhao, Yuqin Liu
Publikováno v:
Cellular Physiology and Biochemistry, Vol 33, Iss 6, Pp 1863-1875 (2014)
Background/Aims: The ubiquitin-specific peptidase USP22 mediates various cellular and organismal processes, such as cell growth, apoptosis, and tumor malignancy. However, the molecular mechanisms that regulate USP22 activity remain poorly understood.
Externí odkaz:
https://doaj.org/article/1866dd0ff81746869c9976e325709314
Autor:
Lukasz Jaroszewski, Zhanwen Li, S Sri Krishna, Constantina Bakolitsa, John Wooley, Ashley M Deacon, Ian A Wilson, Adam Godzik
Publikováno v:
PLoS Biology, Vol 7, Iss 9, p e1000205 (2009)
The genome projects have unearthed an enormous diversity of genes of unknown function that are still awaiting biological and biochemical characterization. These genes, as most others, can be grouped into families based on sequence similarity. The PFA
Externí odkaz:
https://doaj.org/article/a505829aab6b4814b2aa0c900f886bf7
Autor:
Feilin Cao, Zhaosheng Ma, Guinv Hu, Xiaotao Zhu, Shuguang Li, Shuzheng Chen, Binglie Chen, Zhanwen Li, Weizhu Wu, Xiaochun Ji, Jingde Shu, Deyou Tao, Xiaoqing Hu, Min Zheng, Ouchen Wang, Qingjing Feng, Jing Hao, Xujun Li
Publikováno v:
Cancer Research. 83:OT2-14
Objective: Trastuzumab-based adjuvant therapy was demonstrated to improve the prognosis of early human epidermal growth factor receptor 2 (HER-2) positive breast cancer, while about 10% of patients showed primary resistance. ExteNET study showed that
Autor:
Lu Xu, Jin Liu, Yuanqing An, Lei Zhou, Hui Sun, Zhen Xu, Deqiang Wang, Zhanwen Liang, Caihua Xu, Bingyi Wang, Wei Li
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-18 (2024)
Abstract Background Gastric cancer (GC) is a major contributor to cancer-related mortality. Glycolysis plays a pivotal role in tumor microenvironment (TME) reprogramming. In this research, the functions of glycolysis-associated genes (GRGs) were eval
Externí odkaz:
https://doaj.org/article/82218d054ab3498cbff33e1805a7e79f
Publikováno v:
Nucleic Acids Research
Nucleic acids research, vol 48, iss W1
Nucleic acids research, vol 48, iss W1
FATCAT 2.0 server (http://fatcat.godziklab.org/), provides access to a flexible protein structure alignment algorithm developed in our group. In such an alignment, rotations and translations between elements in the structure are allowed to minimize t
Autor:
Zhanwen Li, Fangmeng Fu, Yiding Chen, Jiaojiao Zhou, Qingjian Feng, Honglian Wang, Chuan Wang, Weizhu Wu, Yun Liu
Publikováno v:
Cancer
Background Partner and localizer BRCA2 (PALB2) is a breast cancer predisposition gene, but the clinical relevance of PALB2 germline mutations in Chinese patients with breast cancer remains unknown. This study attempted to investigate the full prevale
Autor:
Qingjian Feng, Yiding Chen, Weizhu Wu, Fangmeng Fu, Yun Liu, Honglian Wang, Hongxia Wang, Zhanwen Li, Chuan Wang, Jiaojiao Zhou
Publikováno v:
Cancer Research. 80:P2-09
Background: PALB2 (Partner and Localizer of BRCA2) is a breast cancer predisposition gene, which plays a critical role in homologous recombination via interacting with BRCA1/2 and RAD51 when DNA break. However, the clinical relevance of PALB2 germlin