Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Zhanwang, Xu"'
Publikováno v:
BioMedical Engineering OnLine, Vol 23, Iss 1, Pp 1-19 (2024)
Abstract Background Primary osteoporosis has increasingly emerged as a major issue affecting human health, with a complex specific pathogenic mechanism. As a research hotspot, ferroptosis plays a vital role in the pathogenesis of primary osteoporosis
Externí odkaz:
https://doaj.org/article/8ed59e4b3af84270b7fe13f3a5233cff
Autor:
Songlin Liang, Nianhu Li, Jiawen Zhan, Zhichao Li, Changjun Tie, Yanjie Zhu, Hongyan Guo, Liqing Ke, Jian Li, Zhanwang Xu, Peng Zhang, Wenxiang Cheng
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-10 (2024)
Abstract Background During the development of disease-modifying intervertebral disc degeneration (IDD) drugs, the rat model of IDD is frequently used for disease progression assessment. The aim of this study was to describe a magnetic resonance (MRI)
Externí odkaz:
https://doaj.org/article/b3a014a3127f4b16a80f126d525bbb6d
Autor:
Hui su, Jun Dong, Luyao Liu, Zechen Yan, Rujie Zhuang, Guangxin Huang, Haipeng Xue, Zhanwang Xu, Yu Pan
Publikováno v:
Pharmacological Research - Modern Chinese Medicine, Vol 13, Iss , Pp 100544- (2024)
Traditional Chinese medicine Gu Sui Bu (Drynaria fortunei J. Smith), has the effect of tonifying the kidneys and strengthening bone. There are many modern studies on the anti-osteoporosis pharmacological mechanism of Gu Sui Bu (Drynaria fortunei J. S
Externí odkaz:
https://doaj.org/article/ccafd94a69ec439bbbf14e021f96e0cd
Autor:
Zhichao Li, Songlin Liang, Liqing Ke, Mengjie Wang, Kuanhui Gao, Dandan Li, Zhanwang Xu, Nianhu Li, Peng Zhang, Wenxiang Cheng
Publikováno v:
Pharmacological Research, Vol 208, Iss , Pp 107383- (2024)
Mitochondria exhibit heterogeneous shapes and networks within and among cell types and tissues, also in normal or osteoporotic bone tissues with complex cell types. This dynamic characteristic is determined by the high plasticity provided by mitochon
Externí odkaz:
https://doaj.org/article/bda1823b9dba42b98bb9452beebf568c
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Bone metabolic diseases have been tormented and are plaguing people worldwide due to the lack of effective and thorough medical interventions and the poor understanding of their pathogenesis. Non-coding RNAs (ncRNAs) are heterogeneous transcripts tha
Externí odkaz:
https://doaj.org/article/0cec861f56924bf1ae292eba7a18940f
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Bone homeostasis depends on a precise dynamic balance between bone resorption and bone formation, involving a series of complex and highly regulated steps. Any imbalance in this process can cause disturbances in bone metabolism and lead to the develo
Externí odkaz:
https://doaj.org/article/a59736a6b64e434f8e86af6174bc9953
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Low back pain has been found as a major cause of global disease burden and disability. Intervertebral disc degeneration is recognized as the vital factor causing low back pain. Intervertebral disc degeneration has a complex mechanism and cannot be av
Externí odkaz:
https://doaj.org/article/182a8d5abe6b480e99bbe6ec145e161c
Autor:
Hui Su, Haipeng Xue, Shang Gao, Binghan Yan, Ruochong Wang, Guoqing Tan, Zhanwang Xu, Lingfeng Zeng
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Osteoporosis is increasingly becoming a serious problem affecting the quality of life of the older population. Several experimental studies have shown that Chinese medicine has a definite effect on improving osteoporosis. Based on transcriptome seque
Externí odkaz:
https://doaj.org/article/9c5cf673d28b49a1bb940bb179c3f4b5
The effect and mechanism of QufengZhitong capsule for the treatment of osteoarthritis in a rat model
Autor:
Wenxiang Cheng, Donghao Gan, Yiping Hu, Zhengtan Zheng, Qingqiang Zeng, Ling Li, Xinluan Wang, Yong Zhang, Zhanwang Xu, Ling Qin, Peng Zhang
Publikováno v:
Journal of Orthopaedic Translation, Vol 28, Iss , Pp 65-73 (2021)
Objective: The purpose of this study was to evaluate the therapeutic effects and mechanism of Qufeng Zhitong (QFZT)capsule for the treatment of osteoarthritis (OA) in a rat model. Methods: 8-10-week-old male Sprague–Dawley rats were randomly divide
Externí odkaz:
https://doaj.org/article/87b78c9ae05d4dd08461f30de3e9744c
Autor:
Donghao Gan, Wenxiang Cheng, Liqing Ke, Antonia RuJia Sun, Qingyun Jia, Jianhai Chen, Zhanwang Xu, Juan Xu, Peng Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Pirfenidone (PFD), a synthetic arsenic compound, has been found to inhibit angiogenesis at high concentrations. However, the biphasic effects of different PFD concentrations on angiogenesis have not yet been elucidated, and the present study used an
Externí odkaz:
https://doaj.org/article/10a9116cee504b0f90017283f43529ae