Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Zhanping Lu"'
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Ultra-conserved RNA (ucRNA) is a subset of long non-coding RNA, that is highly conserved among mice, rats and humans. UcRNA has attracted extensive attention in recent years for its potential biological significance in normal physiological f
Externí odkaz:
https://doaj.org/article/580be06a5f104a33922ec4728365a88d
Autor:
Zhanping Lu, Courtney C. Hong, Guangyao Kong, Anna L.F.V. Assumpção, Irene M. Ong, Emery H. Bresnick, Jing Zhang, Xuan Pan
Publikováno v:
Cell Reports, Vol 22, Iss 6, Pp 1545-1559 (2018)
Summary: Yin yang 1 (YY1) is a ubiquitous transcription factor and mammalian polycomb group protein (PcG) with important functions to regulate embryonic development, lineage differentiation, and cell proliferation. YY1 mediates stable PcG-dependent t
Externí odkaz:
https://doaj.org/article/239ab9bb303d44a690efc5fa8f272d78
Autor:
Tao Zhang, Junping Zhang, Ming Cui, Fabao Liu, Xiaona You, Yumei Du, Yuen Gao, Shuai Zhang, Zhanping Lu, Lihong Ye, Xiaodong Zhang
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 11, Pp 1282-1291 (2013)
The infection of hepatitis B virus (HBV) is closely associated with the development of hepatocellular carcinoma (HCC), in which HBV X protein (HBx) plays crucial roles. MicroRNAs are involved in diverse biologic functions and in carcinogenesis by reg
Externí odkaz:
https://doaj.org/article/be00550712e24469b3d5463f2005357f
Autor:
Rene Welch, Deependra Kumar Singh, Anna L F. V. Assumpção, Ashley M Kuehnl, Renren Wen, Guoping Fu, Xuan Pan, Zhanping Lu, Irene M. Ong
Publikováno v:
Development
Yin Yang 1 (YY1) is a ubiquitous transcription factor and mammalian Polycomb Group protein (PcG) with important functions for regulating lymphocyte development and stem cell self-renewal. YY1 mediates stable PcG-dependent transcriptional repression v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7b6e286f9f4a343540516f5d02aa2c5
https://doi.org/10.1242/dev.197319
https://doi.org/10.1242/dev.197319
Autor:
Matthew A. Van Hesteren, Mike K. Huelsmeyer, Shuai Jia, Anna L F. V. Assumpção, David M. Vail, Xuan Pan, Zhanping Lu, Elizabeth A. Wood
Publikováno v:
Veterinary and comparative oncology. 18(3)
MLN4924 (pevonedistat) is a potent and selective NEDD8-activating enzyme (NAE) inhibitor. The NEDD8-regulated neddylation system is responsible for the regulated degradation of intracellular proteins with important cellular functions in cancer cell g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a73c39289bb0981abc2ee31969df86e5
https://pubmed.ncbi.nlm.nih.gov/31665821
https://pubmed.ncbi.nlm.nih.gov/31665821
Publikováno v:
Biochemical and Biophysical Research Communications. 468:8-13
MicroRNAs acting as oncogenes or tumor suppressor genes play crucial roles in human cancers. Sphingosine kinase 1 (SPHK1) and its metabolite sphingosine 1-phosphate (S1P) contribute to tumor angiogenesis. We have reported that the down-regulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaeeb0452671f80bddcaee3d2870b0d4
https://doi.org/10.1016/j.bbrc.2015.11.008
https://doi.org/10.1016/j.bbrc.2015.11.008
Publikováno v:
Blood. 136:35-35
T cell development originates from hematopoietic stem and progenitor cells in the bone marrow, which migrate to the thymus and obtain T cell identification. Transcription factors play critical roles in regulating early T cell development. While Notch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07b35184d0eabf17e8c7a6bb9dbba35f
https://doi.org/10.1182/blood-2020-139872
https://doi.org/10.1182/blood-2020-139872
Publikováno v:
Blood. 136:27-27
Fetal hematopoietic stem cells (HSCs) exhibit markedly different properties as compared to adult HSCs including cell surface marker expression, proliferation state and repopulation capacity. Changes of HSC activity in postnatal mice is defined by a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::300311b13fd45dc7e3d2a209e0edee8b
https://doi.org/10.1182/blood-2020-137254
https://doi.org/10.1182/blood-2020-137254
Autor:
Fabao Liu, Weiping Li, Jiong Li, Zelin Xiao, Lihong Ye, Ming Cui, Zhanping Lu, Zhe Yang, Xiaodong Zhang
Publikováno v:
Oncotarget
Highly up-regulated in liver cancer (HULC) is a long non-coding RNA (lncRNA). We found that HULC up-regulated sphingosine kinase 1 (SPHK1), which is involved in tumor angiogenesis. Levels of HULC were positively correlated with levels of SPHK1 and it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bd15b5149faf7480f738f58689e42a2
https://doi.org/10.18632/oncotarget.6280
https://doi.org/10.18632/oncotarget.6280
Autor:
Zhe Yang, Xiaodong Zhang, Jiong Li, Fuquan Chen, Yinghui Li, Zelin Xiao, Lihong Ye, Guoxing Feng, Yuen Gao, Zhanping Lu, Jinyan Feng
Publikováno v:
Acta Pharmacologica Sinica. 36:1228-1236
Sphingosine kinase 1 (SPHK1) is involved in various cellular functions, including cell growth, migration, apoptosis, cytoskeleton architecture and calcium homoeostasis, etc. As an oncogenic kinase, SPHK1 is associated with the development and progres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e49e9687d56845c82740765de12c85c3
https://doi.org/10.1038/aps.2015.38
https://doi.org/10.1038/aps.2015.38