Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Zhanna V. Vysotskaya"'
Autor:
Javier González-Maeso, José L. Moreno, Jason Younkin, Lia Baki, Jose M. Eltit, Adishesh Narahari, Diomedes E. Logothetis, Zhanna V. Vysotskaya, Stuart C. Sealfon, Miguel Fribourg, Gyu Park
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 468:775-793
We previously reported that co-expression of the Gi-coupled metabotropic glutamate receptor 2 (mGlu2R) and the Gq-coupled serotonin (5-HT) 2A receptor (2AR) in Xenopus oocytes (Fribourg et al. Cell 147:1011-1023, 2011) results in inverse cross-signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::281dc459f362c72ae7a99270ed4d06ce
https://doi.org/10.1007/s00424-015-1780-7
https://doi.org/10.1007/s00424-015-1780-7
Publikováno v:
Respiratory Physiology & Neurobiology. 203:35-44
This study was carried out to investigate the expression of large-conductance Ca(2+)-activated potassium (BK) channels and to explore the possible modulation of BK channel activities by calcium-sensing receptors (CaSR) in rat bronchopulmonary sensory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c24b3bb2c1ec0e2e11facb015ae733
https://doi.org/10.1016/j.resp.2014.08.014
https://doi.org/10.1016/j.resp.2014.08.014
Publikováno v:
Lung. 192:927-934
Zinc has been known to act as a signaling molecule that regulates a variety of neuronal functions. In this study, we aimed to study the effect of zinc on two populations of acid-sensitive ion channels, acid-sensing ion channels (ASICs), and transient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ef9ae8f18c345d9ff670829e60831f3
https://doi.org/10.1007/s00408-014-9634-1
https://doi.org/10.1007/s00408-014-9634-1
Publikováno v:
Experimental Physiology. 98:1631-1642
New findings • What is the central question of this study? Extracellular calcium-sensing receptor (CaSR) is known to play a critical role in the maintainance of systemic calcium homeostasis. Recent studies suggest that CaSR is also involved in many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b2bfc32cc5f400aa875bcd7d3d225df
https://doi.org/10.1113/expphysiol.2013.074633
https://doi.org/10.1113/expphysiol.2013.074633
Publikováno v:
Biophysical Journal. 100:1226-1232
One major goal of ion channel research is to delineate the molecular events from the detection of the stimuli to the movement of channel gates. For ligand-gated channels, it is challenging to separate ligand binding from channel gating. Here we studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97b643edb02a26714f3a0960759fce86
https://doi.org/10.1016/j.bpj.2011.01.034
https://doi.org/10.1016/j.bpj.2011.01.034
Publikováno v:
Journal of Biological Chemistry. 285:37082-37091
Hyperpolarization-activated cAMP-regulated (HCN) channels play important physiological roles in both cardiovascular and central nervous systems. Among the four HCN isoforms, HCN2 and HCN4 show high expression levels in the human heart, with HCN4 bein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe744eb2a59139fba86f6865fa22a44
https://doi.org/10.1074/jbc.m110.152033
https://doi.org/10.1074/jbc.m110.152033
Publikováno v:
The FASEB Journal. 28
Zinc, a divalent heavy metal ion and an essential trace element in body, functions as a signaling molecule that regulates a variety of neuronal functions. In this study, we examined the effect of zinc on two populations of acid sensitive ion channels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::587b540cb32d3f9f6bbaef8d8e655992
https://doi.org/10.1096/fasebj.28.1_supplement.712.3
https://doi.org/10.1096/fasebj.28.1_supplement.712.3
Publikováno v:
Experimental physiology. 98(11)
Extracellular calcium-sensing receptor (CaSR) has been known to play a critical role in the maintainance of systemic Ca(2+) homeostasis. Recent studies have shown that CaSR is also expressed in many tissues that are not directly related to plasma Ca(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3b682dccc12781bc25318aa124b1cd77
https://pubmed.ncbi.nlm.nih.gov/23913765
https://pubmed.ncbi.nlm.nih.gov/23913765
Publikováno v:
The FASEB Journal. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02fe1ea84c76f0ed5ac5526f7bf51f85
https://doi.org/10.1096/fasebj.27.1_supplement.1214.12
https://doi.org/10.1096/fasebj.27.1_supplement.1214.12
Autor:
Zhanna V. Vysotskaya, Miguel Fribourg, Gyu Park, Amr Ellaithy, Jason Younkin, Jose M. Eltit, Diomedes E. Logothetis, Lia Baki
Publikováno v:
Biophysical Journal. 108:416a
Atypical antipsychotic drugs targeting the 5-HT2A receptor (2AR) are widely used in the treatment of schizophrenia and psychosis. Recent studies point to a new class of potential antipsychotic drugs targeting the metabotropic glutamate receptor 2 (mG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf9814699c5dcf21eb00da0a614c2dd3
https://doi.org/10.1016/j.bpj.2014.11.2280
https://doi.org/10.1016/j.bpj.2014.11.2280