Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Zhanna A. Afonina"'
Publikováno v:
International Journal of Biomedicine, Vol 9, Iss Suppl_1, Pp S22-S23 (2019)
Background: Cryo-electron tomography (cryo-ET) is currently the only technique that can be used for quaternary structure determination of polyribosomal complexes under near physiological conditions. Here we describe, in more detail, the cryo-ET pipel
Externí odkaz:
https://doaj.org/article/834ea325d5fe4625b5e1e078b7372224
Autor:
Elena M. Maksimova, Alexey P. Korepanov, Olesya V. Kravchenko, Timur N. Baymukhametov, Alexander G. Myasnikov, Konstantin S. Vassilenko, Zhanna A. Afonina, Elena A. Stolboushkina
Publikováno v:
International Journal of Biomedicine, Vol 11, Iss Suppl_1, Pp 23-24 (2021)
Background: Ribosome biogenesis is a complicated multi-stage process. In the cell, 30S ribosomal subunit assembly is fast and efficient, proceeding with the help of numerous assembly protein factors. The exact role of most assembly factors and mechan
Externí odkaz:
https://doaj.org/article/c52af8f11e6942f7a6289987546b4025
Autor:
Zhanna A. Afonina, Timur N. Baymukhametov, Dmitry N. Lyabin, Yury M. Chesnokov, Alexander L. Vasiliev, Vladimir A. Shirokov
Publikováno v:
International Journal of Biomedicine, Vol 9, Iss Suppl_1, Pp S22-S22 (2019)
Background: Polyribosomes are complexes consisting of several ribosomes simultaneously translating a single mRNA molecule. In early electron microscopy studies, it was shown that eukaryotic polyribosomes in cells can have various shapes – rings, do
Externí odkaz:
https://doaj.org/article/7653dfe5127e46eca97d0e83e3cc4fb2
Publikováno v:
International Journal of Biomedicine, Vol 11, Iss Suppl_1, Pp 20-20 (2021)
Background: The ribosome is a molecular machine that translates mRNAs into proteins. In eukaryotes, ribosome consists of small (40S) and large (60S) subunits. Translation in eukaryotes is a complicated molecular process that involves the formation of
Externí odkaz:
https://doaj.org/article/a2e3d80df67b4f479a4cade30ce56ee5
Autor:
Timur N Baymukhametov, Dmitry N Lyabin, Yury M Chesnokov, Ivan I Sorokin, Evgeniya V Pechnikova, Alexander L Vasiliev, Zhanna A Afonina
Publikováno v:
Nucleic acids research.
Polyribosomes, the groups of ribosomes simultaneously translating a single mRNA molecule, are very common in both, prokaryotic and eukaryotic cells. Even in early EM studies, polyribosomes have been shown to possess various spatial conformations, inc
Autor:
A. P. Korepanov, Zhanna A. Afonina, Konstantin S. Vassilenko, O. V. Kravchenko, Alexander G. Myasnikov, Timur Baymukhametov, Elena Maksimova, Elena Stolboushkina
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6140, p 6140 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 11
International Journal of Molecular Sciences
Volume 22
Issue 11
Ribosome biogenesis is a highly coordinated and complex process that requires numerous assembly factors that ensure prompt and flawless maturation of ribosomal subunits. Despite the increasing amount of data collected, the exact role of most assembly
Autor:
A. P. Korepanov, Zhanna A. Afonina, Elena Stolboushkina, Elena Maksimova, O. V. Kravchenko, Alexander G. Myasnikov, Timur Baymukhametov, Konstantin S. Vassilenko
Publikováno v:
International Journal of Biomedicine, Vol 11, Iss Suppl_1, Pp 23-24 (2021)
Background: Ribosome biogenesis is a complicated multi-stage process. In the cell, 30S ribosomal subunit assembly is fast and efficient, proceeding with the help of numerous assembly protein factors. The exact role of most assembly factors and mechan
Autor:
Alexander L. Vasiliev, V.A. Shirokov, Timur Baymukhametov, Zhanna A. Afonina, Yury Chesnokov, Dmitry Lyabin
Publikováno v:
International Journal of Biomedicine, Vol 9, Iss Suppl_1, Pp S22-S22 (2019)
Background: Polyribosomes are complexes consisting of several ribosomes simultaneously translating a single mRNA molecule. In early electron microscopy studies, it was shown that eukaryotic polyribosomes in cells can have various shapes – rings, do
Publikováno v:
International Journal of Biomedicine, Vol 11, Iss Suppl_1, Pp 20-20 (2021)
Background: The ribosome is a molecular machine that translates mRNAs into proteins. In eukaryotes, ribosome consists of small (40S) and large (60S) subunits. Translation in eukaryotes is a complicated molecular process that involves the formation of
Autor:
Zhanna A. Afonina, V.A. Shirokov, Bruno P. Klaholz, Alexander S. Spirin, Alexander G. Myasnikov
Publikováno v:
Nucleic Acids Research
Using sedimentation and cryo electron tomography techniques, the conformations of eukaryotic polyribosomes formed in a long-term cell-free translation system were analyzed over all the active system lifetime (20–30 translation rounds during 6–8 h